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In the 20th century, poliomyelitis emerged to become a global crippler and killer. But, with the development of preventive vaccines in the 1950s, it looks set to be the first disease to be eliminated by direct human intervention. Divided into four parts, this book presents a world geography of poliomyelitis.
Completely revised and updated, this respected reference offers comprehensive and current coverage of every aspect of vaccination-from development to use in reducing disease. It provides authoritative information on vaccine production, available preparations, efficacy, and safety...recommendations for vaccine use, with rationales...data on the impact of vaccination programs on morbidity and mortality...and more. And now, as an Expert Consult title, it includes a companion web site offering this unparalleled guidance where and when you need it most! Provides a complete understanding of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well an epidemiology and public health issues. Offers comprehensive coverage of both existing vaccines and vaccines currently in the research and development stage. Examines vaccine stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease control strategies. Analyses the cost-benefit and cost-effectiveness of vaccines. Discusses the proper use of immune globulins and antitoxins. Illustrates concepts and objective data with approximately 600 tables and figures. Includes access to a companion web site offering the complete contents of the book - fully searchable - for rapid consultation from anyplace with an Internet connection.
Vols. 28-30 accompanied by separately published parts with title: Indices and necrology.
Polio--often called the "summer plague"--struck hundreds of thousands of children around the world between its emergence as an epidemic disease in 1916 to its cure in the 1950s. Today, images of children with crutches and leg braces or encased to their necks in iron lungs may be little more than a painful memory. Yet during its height the disease induced panic on a scale reminiscent of the great plagues of history. This book is the most comprehensive and compelling account of the century's polio epidemics yet written. Interweaving biographical, political, social, and medical history, Tony Gould--a distinguished British writer and himself a polio survivor--traces the rise and fall of the epidemics and describes the individuals who were influential in its treatment and conquest. He tells of Franklin D. Roosevelt, the most celebrated polio sufferer of all, who set up his own hydrotherapy center at Warm Springs in Georgia; John Enders, the Nobel prizewinner who made the crucial breakthrough in the laboratory; FDR's lieutenant, Basil O'Connor, whose "March of Dimes" became a byword for successful fund-raising; Sister Elizabeth Kenny, the larger-than-life nurse from the Australian outback who challenged medical orthodoxy and invented "miracle" cures; and finally the scientific rivals Jonas Salk and Albert Sabin, caught in a dramatic race to produce a viable vaccine. Gould then examines the experience of polio survivors on both sides of the Atlantic, including a moving autobiographical account of his own struggle with the disease and resulting disability. Although the disease has been eliminated in the West, it has not disappeared: paralytic polio remains a scourge in India, the Far East, and parts of Africa. And there are new worries that fatigue and accelerated muscular weakness--a "post-polio syndrome"--has come to afflict survivors three or four decades after the initial attack. Gould's powerful book, published forty years after the successful trial of the Salk vaccine, helps us to understand the savage and continuing impact of polio.
Hygiene.