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Ivory is fourteen years old and is madly in love with fifteen-year-old Blake. She hangs out with a tough older crowd, drinks, smokes, and even has a pregnancy scare. One night Ivory doesn't come home. Her body is found a few months later, brutally stabbed to death. Blake stands accused of her murder, but the evidence is inconclusive. Who murdered Ivory Towle? Will the truth ever be known?
ALICE FEENEYS NEW YORK TIMES AND INTERNATIONAL BESTSELLER “Boldly plotted, tightly knotted—a provocative true-or-false thriller that deepens and darkens to its ink-black finale. Marvelous.” —AJ Finn, author of The Woman in the Window My name is Amber Reynolds. There are three things you should know about me: 1. I’m in a coma. 2. My husband doesn’t love me anymore. 3. Sometimes I lie. Amber wakes up in a hospital. She can’t move. She can’t speak. She can’t open her eyes. She can hear everyone around her, but they have no idea. Amber doesn’t remember what happened, but she has a suspicion her husband had something to do with it. Alternating between her paralyzed present, the week before her accident, and a series of childhood diaries from twenty years ago, this brilliant psychological thriller asks: Is something really a lie if you believe it's the truth?
The End centers on five friends in Rio de Janeiro who, nearing the end of their lives, are left with memories—of parties, marriages, divorces, fixations, inhibitions, bad decisions—and the physical indignities of aging. Alvaro lives alone and spends his time going from doctor to doctor and bemoaning the evils of his ex-wife. Silvio is a junkie who can’t give up the excesses of sex and drugs even in his old age. Ribeiro is an athletic beach bum enjoying a prolonged sex life thanks to Viagra. Neto is the square member of the group, a faithful husband until his last days. And Ciro is the Don Juan envied by all—but the first to die, struck down by cancer. For all of them, successful careers, personal revelations, and Zen serenity are out of the question, blocked by a seemingly insurmountable wall of frustrations. Orbiting around them are a priest questioning his vocation and a cast of complicated women, neglected and embattled by these self-involved men. Edgy and wise, this tragicomic debut delves into taboo subjects—death, infidelity, impotence, the difficulties of marriage—with unsentimental honesty, and brings Rio and these characters to life in full color.
Eli Monpress is clever, he's determined, and he's in way over his head. First rule of thievery: don't be a hero. When Eli broke the rules and saved the Council Kingdoms, he thought he knew the price, but resuming his place as the Shepherdess's favorite isn't as simple as bowing his head. Now that she has her darling back, Benehime is setting in motion a plan that could destroy everything she was created to protect, and even Eli's charm might not be enough to stop her. But Eli Monpress always has a plan, and with disaster rapidly approaching, he's pulling in every favor he can think of to make it work, including the grudging help of the Spirit Court's new Rector, Miranda Lyonette. But with the world in panic, the demon stirring, and the Lord of Storms back on the hunt, it's going to take more than luck and charm to pull Eli through this time. He's going to have to break a few more rules and work with some old enemies if he's going to survive.
I had to accept that I wasn’t just Arthur Leywin anymore, and that I could no longer be limited by the circumstances of my birth. If I was going to escape, if I was going to go toe-to-toe with the most powerful beings in this world, I needed to push myself to my utmost limit...and then I needed to push even further. After nearly dying as a victim of his own strength, Arthur Leywin wakes to find himself far from the continent where he was born for the second time. Alone, broken, and with no way to tell his family he’s alive, Arthur must rebuild his strength to survive. As he ascends through an ancient dungeon filled with hostile beasts and devious trials, he discovers an ancient, absolute power - a power that will either ruin him or take him to new heights. But the dungeon won’t give up its knowledge easily. Before he can plunder its depths, Arthur must learn to untangle the threads of fate. He must band together with the unlikeliest of allies if he hopes to escape with his life.
Do we know what it means to question well? We need not fear questions, but by the grace of God, we have the safety and security to rush headlong into them and find ourselves better for it on the other side. Faith isn't the sort of thing that will endure as long as our eyes are closed. The opposite is the case: Faith helps us see, and that means not shrinking from the ambiguities and the difficulties that provoke our most profound questions. In our embrace of questioning, we must learn to question well. In our uncertainty, we must not give up the task of walking worthy of the calling that Christ has placed upon us. For we have not yet reached the end of our exploring. This book is written to aid you in faithfully questioning your foundations.
When Alex falls for the charming new boy at school, Cole -- a handsome, funny, sports star who adores her -- she can't believe she's finally found her soul mate . . . someone who truly loves and understands her. At first, Alex is blissfully happy. Sure, Cole seems a little jealous of her relationship with her close friend Zack, but what guy would want his girlfriend spending all her time with another boy? As the months pass, though, Alex can no longer ignore Cole's small put-downs, pinches, or increasingly violent threats. As Alex struggles to come to terms with the sweet boyfriend she fell in love with and the boyfriend whose "love" she no longer recognizes, she is forced to choose -- between her "true love" and herself.
From the #1 New York Times bestselling author of This Is Where It Ends comes another heartbreaking, emotional and timely page-turner that will keep you on the edge of your seat. The Hope Juvenile Treatment Center is ironically named. No one has hope for the delinquent teenagers who have been exiled there; the world barely acknowledges that they exist. Then the guards at Hope start acting strange. And one day...they don't show up. But when the teens band together to make a break from the facility, they encounter soldiers outside the gates. There's a rapidly spreading infectious disease outside, and no one can leave their houses or travel without a permit. Which means that they're stuck at Hope. And this time, no one is watching out for them at all. As supplies quickly dwindle and a deadly plague tears through their ranks, the group has to decide whom among them they can trust and figure out how they can survive in a world that has never wanted them in the first place. Also by Marieke Nijkamp: This Is Where It Ends Even If We Break Before I Let Go Praise for Marieke Nijkamp: "Immersive and captivating. Thrilling in every sense of the word."—Karen M. McManus, #1 New York Times bestselling author of One of Us is Lying on Even If We Break "With exceptional handling of everything from mental illness to guilt and a riveting, magic realist narrative, this well wrought, haunting novel will stick with readers long after the final page."—Booklist on Before I Let Go *STARRED REVIEW* "A compelling, brutal story of an unfortunately all-too familiar situation: a school shooting. Nijkamp portrays the events thoughtfully, recounting fifty-four intense minutes of bravery, love, and loss."—BookRiot on This Is Where It Ends
Book five of The Belgariad_
This book provides detailed protocols and untold tips and tricks regarding the most well-known examples of proximity labeling methods, in which the protein of interest is genetically fused to or labeled with an enzyme that can generate short-lived reactive species to non-specifically label molecules within a certain radius of up to twenty nanometers. Beginning with peroxidase-based proximity labeling methods, the volume continues with BioID, proximity labeling methods that describe the proximity ligation assay to detect RNA-DNA interactions, UV cross-linking to demonstrate RNA-protein interactions, and how chemical and enzymatic reactivities can be improved upon DNA-DNA and protein-protein interactions, as well as “proximity-induced self-labeling,” where the radius of labeling is zero. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Proximity Labeling: Methods and Protocols serves as an ideal guide for researchers exploring the crucial roles that proximity-driven reactions play in biological systems.