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The Dynamic Energy Budget theory unifies the commonalities between organisms and links different levels of biological organisation.
The Dynamic Energy Budget theory unifies the commonalties between organisms, as prescribed by the implications of energetics, and links different levels of biological organisation (cells, organisms and populations). The theory presents simple mechanistic rules that describe the uptake and use of energy and nutrients and the consequences for physiological organization throughout an organism's life cycle. All living organisms are covered in a single quantitative framework, the predictions of which are tested against a variety of experimental results at a range of levels of organisation. The theory explains many general observations, such as the body size scaling relationships of certain physiological traits, and provides a theoretical underpinning to the method of indirect calorimetry. In each case, the theory is developed in elementary mathematical terms, but a more detailed discussion of the methodological aspects of mathematical modelling is also included.
A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid
Social pressure to minimize the use of animal testing, the ever-increasing concern on animal welfare, and the need for more human-relevant and more predictive toxicity tests are some of the drivers for new approaches to chemical screening. This book focuses on The Adverse Outcome Pathway, an analytical construct that describes a sequential chain of causally linked events at different levels of biological organization that lead to an adverse health or ecotoxicological effect. While past efforts have focused on toxicological pathway-based vision for human and ecological health assessment relying on in vitro systems and predictive models, The Adverse Outcome Pathway framework provides a simplified and structured way to organize toxicological information. Within the book, a systems biology approach supplies the tools to infer, link, and quantify the molecular initiating events and the key events and key event relationships leading to adverse outcomes. The advancement of these tools is crucial for the successful implementation of AOPs for regulatory purposes.
From climate change to species extinction, humanity is confronted with an increasing array of societal and environmental challenges that defy simple quantifiable solutions. Complexity-based ecology provides a new paradigm for ecologists and conservationists keen to embrace the uncertainty that is pressed upon us. This book presents key research papers chosen by some sixty scholars from various continents, across a diverse span of sub-disciplines. The papers are set alongside first person commentary from many of the seminal voices involved, offering unprecedented access to experts' viewpoints. The works assembled also shed light on the process of science in general, showing how the shifting of wider perspectives allows for new ideas to take hold. Ideal for undergraduate and advanced students of ecology and conservation, their educators and those working across allied fields, this is the first book of its kind to focus on complexity-based approaches and provides a benchmark for future collected volumes.
Elegant, novel explanation of climate change, emphasizing physical understanding and concepts, while avoiding complex mathematics, supported by excellent color illustrations.
It is almost thirty years since Professor G. G. Winberg established the basis for experimental studies in fish energetics with the publication of his monograph, Rate of Metabolism and Food Requirements of Fishes. His ultimate aim was to develop a scientific approach to fish culture and management, and the immense volume of literature generated in the ensuing years has been mainly in response to the demand for information from a rapidly expanding, world-wide aquaculture industry and to the shortcomings of contemporary practices in fisheries management. The purpose of this book is not to review this literature compre hensively, but, assuming an informed readership, to focus attention on topics in which new knowledge and theory are beginning to be applied in practice. Most emphasis has been placed on food; feeding; production (growth and reproduction) and energy budgeting, as these have most influence on the development of fish culture. Some chapters offer practical advice for the selection of methods, and warn of pitfalls in previous approaches. In others the influence of new theory on the interpretation of studies in fish energetics is discussed in the context of resource allocation and adaptation. We hope that the scope of material presented here will have sufficient interest and value to help significantly to fulfil Winberg's original objectives.
With the expansion of the world aquaculture industry, there has been increasing concern over sustainability and environmental impact. This book addresses this topical issue, concentrating on marine aquaculture.
Crustaceans adapt to a wide variety of habitats and ways of life. They have a complex physiological structure particularly with regard to the processes of growth (molting), metabolic regulation, and reproduction. Crustaceans are ideal as model organisms for the study of endocrine disruption and stress physiology in aquatic invertebrates. This book