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The progress in HLA research achieved in the last decade has been extremely beneficial for understanding of the human genome structure, evolution of human beings and the association between HLA and complex related factors like immune responsiveness and patomechanism of some diseases. It was also found that some HLA specificities may bear a witness not only to a susceptibility to some diseases but also may reflect the ability of the host to mount immune responsiveness. All these achievements enabled successful clinical application of haematopoietic stem cells transplantation. Nowadays, it is apparent that the perfect matching at allele level of HLA specificities constitute the most important factor affecting surviving of patients transplanted from unrelated donors. This is also shown in this volume. To secure reliability of HLA typing , DNA techniques should be implemented and laboratories should comply with requirements expressed by European Federation for Immunogenetics (EFI) and American Society for Histocompatibility and Immunogenetics (ASHI). HLA typing is a complex procedure which should involve internal and external quality controls. Haematopoietic stem cell transplantation may be the best example of introducing modern technologies and very active translation of basic research in the fields of genetics and cell biology into the clinic. Even more impressive is international collaboration in searching for the best possible donor wherever in the world it might be. More than 8 million donors are registered world-wide. There is an ongoing interest in improving the international co-operation in order to secure the best donors for recipients. These chapters are of special interest as the co-operation for donors selection for HSCT is an activity across the oceans.
The WHO guidelines on assessing donor suitability for blood donation have been developed to assist blood transfusion services in countries that are establishing or strengthening national systems for the selection of blood donors. They are designed for use by policy makers in national blood programmes in ministries of health, national advisory bodies such as national blood commissions or councils, and blood transfusion services.
Applying the principles of marketing to nonprofit organizations and the fundraising sector is vital for the modern fundraiser who wants to increase profitability and diversify their fundraising efforts in this challenging industry. This comprehensive how-to guide provides a thorough grounding in the principles underpinning professional practices and critically examines the key issues in fundraising policy, planning and implementation. This new edition of Fundraising Management builds on the successful previous editions by including modern perspectives on organizational behaviour, extended coverage of digital fundraising and donor behaviour, including an examination of group influences on behaviour, and a new chapter on the use of social media for supporter engagement and retention. Combining scholarly analysis with practical real life examples, Fundraising Management has been endorsed by the Institute of Fundraising, and is mapped to the Certificate and Diploma in Fundraising, making it the definitive guide to best practice both in the UK and globally. This is a clear, problem-solving guide that no fundraising student or professional should be without.
Ensuring the safety of blood for transfusion is a key prevention strategy in the fight against HIV/AIDS. These learning materials have been designed specifically for use in distance learning programmes in blood safety. The modules have been designed for staff responsible for donor recruitment, blood collection and the processing and issue of blood for transfusion. They are written in an interactive, practical style, with learning objectives, activities, self-assessment questions, progress checks and action plans Most of the training is designed to take place at the workplace in the context of the performance of daily work. This pack consists of a set of four spiral-bound modules and a Trainer's Guide, all supplied in a plastic wallet.
Transfusion Medicine provides a concise, clinically focused and practical approach to the field of blood banking and transfusion therapy written by international expert, Jeffrey McCullough MD. Concise, approachable, yet comprehensive approach to the field of transfusion medicine and blood banking Offers extensive guidance on important topics such as; donor recruitment, blood collection and storage, donor testing and clinical uses of blood components, techniques of administration of blood components, complications of transfusion, transmissible diseases, the HLA system, and many more Provides new content on patient blood management systems, the changing indications for red cell transfusion, new transmissible disease agents, management of massive blood loss, pathogen reduced blood components, therapeutic apheresis including photopheresis, management of massive transfusion and new cellular therapies. Discusses global blood supply and US blood supply organizations and their consolidation and reorganization Reviews other topics of current interest, such as mitigation strategies for TRALI prevention, effects of storage of blood on adverse effects, management of massive blood loss and massive transfusion protocols pathogen inactivation, and granulocyte transfusion Extensively referenced for further study
Jeffrey McCullough offers a concise, clinically focused and practical approach to this important area of medicine. This book offers complete guidance on the full range of topics from donor recruitment, blood collection and storage, to testing and transfusing blood components, complications and transmissible diseases, as well as cellular engineering, therapeutic apheresis, and the role of hematopoietic growth factors. It is a good introduction to transfusion for hematology or oncology fellows and technologists specialising in blood banking.