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Deoxyribonucleic acid, or DNA, is the fundamental building block for an individual's entire genetic makeup. DNA is a powerful tool for law enforcement investigations because each person's DNA is different from that of every other individual (except for identical twins). DNA can be extracted from a number of sources, such as hair, bone, teeth, saliva, and blood. As early as the 1980s, states began enacting laws that required collecting DNA samples from offenders convicted of certain sexual and other violent crimes. The samples were then analyzed and their profiles entered into state databases. Meanwhile, the Federal Bureau of Investigation (FBI) Laboratory convened a working group of federal, state, and local forensic scientists to establish guidelines for the use of forensic DNA analysis in laboratories. The group proposed guidelines that are the basis of current national quality assurance standards, and it urged the creation of a national DNA database. The criminal justice community began to utilize DNA analyses more often in criminal investigations and trials, and in 1994 Congress enacted legislation to authorize the creation of a national DNA database. Federal law (42 U.S.C §14132(a)) authorizes the FBI to operate and maintain a national DNA database where DNA profiles generated from samples collected from people under applicable legal authority and samples collected at crime scenes can be compared to generate leads in criminal investigations. Statutory provisions also authorize the collection of DNA samples from federal offenders and arrestees, District of Columbia offenders, and military offenders. State laws dictate which convicted offenders, and sometimes people arrested for crimes, will have profiles entered into state DNA databases, while federal law dictates the scope of the national database. Increasing awareness of the power of DNA to solve crimes has resulted in increased demand for DNA analysis, which has resulted in a backlog of casework. Some jurisdictions have started to use their DNA databases for familial searching, which involves using offender profiles to identify relatives who might be perpetrators of crimes. In addition to solving crimes, DNA analysis can help exonerate people incarcerated for crimes they did not commit. Congress has authorized several grant programs to provide assistance to state and local governments for forensic sciences. Many of the programs focus on providing state and local governments with funding to reduce the backlog of forensic and convicted offender DNA samples waiting to be processed and entered into the national database. Since FY2006, Congress has appropriated approximately $785 million for backlog reduction and laboratory capacity enhancement programs. However, other grant programs provide funding for related purposes, such as offsetting the cost of providing post-conviction DNA testing. In the 1990s and the early part of the last decade, most of the debate in Congress focused on the scope of DNA databases, reducing the backlog of DNA casework, and providing access to post conviction DNA testing. Most of the debate about the scope of DNA databases faded away with the enactment of the Violence Against Women and Department of Justice Reauthorization Act of 2005 (P.L. 109-162), which expanded federal collection statutes to include anyone arrested or detained under the authority of the United States. The act also expanded the scope of the national database to include DNA profiles of individuals arrested for state crimes. However, concerns about the backlog of DNA casework and access to post-conviction testing have persisted. In addition, new issues related to the use of DNA in criminal justice have emerged, including whether (1) DNA databases should be used to conduct familial searches, (2) sexual assault evidence collection kits (i.e., “rape kits”) should be standardized, and (3) there should be national accreditation standards for forensic laboratories.
Deoxyribonucleic acid, or DNA, is the fundamental building block for an individual's entire genetic makeup. DNA is a powerful tool for law enforcement investigations because each person's DNA is different from that of every other individual (except for identical twins). DNA can be extracted from a number of sources, such as hair, bone, teeth, saliva, and blood. As early as the 1980s, states began enacting laws that required collecting DNA samples from offenders convicted of certain sexual and other violent crimes. The samples were then analyzed and their profiles entered into state databases. Meanwhile, the Federal Bureau of Investigation (FBI) Laboratory convened a working group of federal, state, and local forensic scientists to establish guidelines for the use of forensic DNA analysis in laboratories. The group proposed guidelines that are the basis of current national quality assurance standards, and it urged the creation of a national DNA database. The criminal justice community began to utilize DNA analyses more often in criminal investigations and trials, and in 1994 Congress enacted legislation to authorize the creation of a national DNA database. Federal law (42 U.S.C §14132(a)) authorizes the FBI to operate and maintain a national DNA database where DNA profiles generated from samples collected from people under applicable legal authority and samples collected at crime scenes can be compared to generate leads in criminal investigations. Statutory provisions also authorize the collection of DNA samples from federal offenders and arrestees, District of Columbia offenders, and military offenders. State laws dictate which convicted offenders, and sometimes people arrested for crimes, will have profiles entered into state DNA databases, while federal law dictates the scope of the national database. Increasing awareness of the power of DNA to solve crimes has resulted in increased demand for DNA analysis, which has resulted in a backlog of casework. Some jurisdictions have started to use their DNA databases for familial searching, which involves using offender profiles to identify relatives who might be perpetrators of crimes. In addition to solving crimes, DNA analysis can help exonerate people incarcerated for crimes they did not commit. Congress has authorized several grant programs to provide assistance to state and local governments for forensic sciences. Many of the programs focus on providing state and local governments with funding to reduce the backlog of forensic and convicted offender DNA samples waiting to be processed and entered into the national database. However, other grant programs provide funding for related purposes, such as offsetting the cost of providing post-conviction DNA testing.
In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.
Examines the impact of DNA technology on issues of ethics, civil liberties, privacy, and security.
Matching DNA samples from crime scenes and suspects is rapidly becoming a key source of evidence for use in our justice system. DNA Technology in Forensic Science offers recommendations for resolving crucial questions that are emerging as DNA typing becomes more widespread. The volume addresses key issues: Quality and reliability in DNA typing, including the introduction of new technologies, problems of standardization, and approaches to certification. DNA typing in the courtroom, including issues of population genetics, levels of understanding among judges and juries, and admissibility. Societal issues, such as privacy of DNA data, storage of samples and data, and the rights of defendants to quality testing technology. Combining this original volume with the new update-The Evaluation of Forensic DNA Evidence-provides the complete, up-to-date picture of this highly important and visible topic. This volume offers important guidance to anyone working with this emerging law enforcement tool: policymakers, specialists in criminal law, forensic scientists, geneticists, researchers, faculty, and students.
Forensic DNA Applications: An Interdisciplinary Perspective was developed as an outgrowth of a conference held by the International Society of Applied Biological Sciences. The topic was human genome–based applications in forensic science, anthropology, and individualized medicine. Assembling the contributions of contributors from numerous regions around the world, this volume is designed as both a textbook for forensic molecular biology students and a reference for practitioners and those in the legal system. The book begins with the history and development of DNA typing and profiling for criminal and civil purposes. It discusses the statistical interpretation of results with case examples, mitochondrial DNA testing, Y single nucleotide polymorphisms (SNPs) and short tandem repeats (STRs), and X SNP and STR testing. It also explores low copy number DNA typing, mixtures, and quality assurance and control. The second section examines the collection and preservation of biological evidence under a variety of different circumstances and the identification of human remains—including in mass disaster settings. It discusses applications to bioterrorism investigations, animal DNA testing in criminal cases, pedigree questions and wildlife forensic problems, applications in forensic entomology, and forensic botany. The third section explores recent developments and new technologies, including the rigorous identification of tissue of origin, mtDNA profiling using immobilized probe strips, chips and next-generation sequencing, the use of SNPs to ascertain phenotypic characteristics, and the "molecular autopsy" that looks at aspects of toxicogenetics and pharmacogenetics. The book concludes with a discussion on law, ethics, and policy. It examines the use of DNA evidence in the criminal justice system in both the United States and Europe, ethical issues in forensic laboratory practices, familial searches, DNA databases, ancestry searches, physical phenotyping, and report writing. The contributors also examine DNA applications in immigration and human trafficking cases and international perspectives on DNA databases.
In recent years forensic DNA evidence has been used by agencies and actors in the criminal justice system more and more frequently to both convict the guilty and exonerate the innocent. Cases that previously may have been unsolveable have been transformed into solvable cases where viable suspects can be identified and arrested or removed from suspect lists. This book presents examinations of how DNA, and some other forensic methods, are being used by our justice system and the issues that surround these uses.
Forensic DNA analysis was first introduced to the American criminal justice system in the mid-1980s. In spite of its relatively brief existence in American jurisprudence, DNA testing has become the leading forensic tool for obtaining sexual assault criminal convictions, and the single most powerful evidence for establishing the innocence of criminal suspects and wrongfully convicted defendants. The development of DNA "fingerprinting" and the role it has played in the American criminal justice system is covered in this encyclopedia. Numerous entries explain the relationship of forensic DNA analysis with microbiology, population genetics, statistics, and the legal rules of the admissibility of scientific evidence. The encyclopedia also presents the full text, preceded by summaries, of all state and federal government statutes that address the forensic use of DNA analysis, and the edited text of judicial case opinions that address specific forensic DNA issues. Also included are entries on many of the organizations that use DNA fingerprinting to free wrongly convicted defendants and many of the individuals who were released from prison (many of whom were on death row) after DNA testing proved their innocence.