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The new and updated edition of this book explains the key steps in planning and executing diagnostic test accuracy studies in dementia, serving as an introduction to the topic with clear explanations of difficulties and pitfalls. It has been fully revised in light of developments over the past 5 years and includes STARD publications which have appeared since the first edition as well as the use of biomarkers of cognitive disorders as increasingly enshrined in diagnostic criteria. The book covers the presentation of study results in terms of measures of discrimination, taking examples from studies in dementia looking at various diagnostic methods including cognitive instruments, neuroimaging, and biochemical studies. The book continues to reflect the author’s own experience in diagnostic test accuracy studies, particularly in the sphere of cognitive screening instruments.. Diagnostic Test Accuracy Studies in Dementia encourages clinicians to adopt a pragmatic approach to diagnostic test accuracy studies rooted in day-to-day clinical practice.
This book describes statistical techniques for the design and evaluation of research studies on medical diagnostic tests, screening tests, biomarkers and new technologies for classification and prediction in medicine.
This revised and updated second edition provides a practical and structured overview of some of the most commonly used and easily available cognitive screening instruments applicable in the outpatient clinic and bedside setting. It now includes additional chapters on AD8 and also methodological aspects of systematic cognitive screening instrument assessment from the Cochrane Dementia and Cognitive Improvement Group. Expert authors from around the world equip the reader with clear instructions on the usage of each screening instrument, its strengths and weaknesses, and the time required for administration. Rules on scoring are also provided, such as how to correct for variations in the patient’s age or education, and suggested cut-off scores. Cognitive Screening Instruments: A Practical Approach, Second Edition is aimed at both clinicians and professionals in disciplines allied to medicine who are called upon to assess patients with possible cognitive disorders, including neurologists, old age psychiatrists, neuropsychologists, primary care physicians, dementia support workers, and members of memory assessment teams.
This report provides a comprehensive picture of dementia in Australia, illustrated by the latest available data and information on trends over time.
New edition, completely rewritten, with new chapters on endovascular surgery and mitochrondrial and ion channel disorders.
Explains the mathematics involved in understanding and choosing an array of diagnostic and prognostic tests, in order to improve treatment.
A broad and in-depth discussion of the important, but still uninformed, field of behavioral disturbances associated with Parkinson's disease.
As the largest generation in U.S. history - the population born in the two decades immediately following World War II - enters the age of risk for cognitive impairment, growing numbers of people will experience dementia (including Alzheimer's disease and related dementias). By one estimate, nearly 14 million people in the United States will be living with dementia by 2060. Like other hardships, the experience of living with dementia can bring unexpected moments of intimacy, growth, and compassion, but these diseases also affect people's capacity to work and carry out other activities and alter their relationships with loved ones, friends, and coworkers. Those who live with and care for individuals experiencing these diseases face challenges that include physical and emotional stress, difficult changes and losses in their relationships with life partners, loss of income, and interrupted connections to other activities and friends. From a societal perspective, these diseases place substantial demands on communities and on the institutions and government entities that support people living with dementia and their families, including the health care system, the providers of direct care, and others. Nevertheless, research in the social and behavioral sciences points to possibilities for preventing or slowing the development of dementia and for substantially reducing its social and economic impacts. At the request of the National Institute on Aging of the U.S. Department of Health and Human Services, Reducing the Impact of Dementia in America assesses the contributions of research in the social and behavioral sciences and identifies a research agenda for the coming decade. This report offers a blueprint for the next decade of behavioral and social science research to reduce the negative impact of dementia for America's diverse population. Reducing the Impact of Dementia in America calls for research that addresses the causes and solutions for disparities in both developing dementia and receiving adequate treatment and support. It calls for research that sets goals meaningful not just for scientists but for people living with dementia and those who support them as well. By 2030, an estimated 8.5 million Americans will have Alzheimer's disease and many more will have other forms of dementia. Through identifying priorities social and behavioral science research and recommending ways in which they can be pursued in a coordinated fashion, Reducing the Impact of Dementia in America will help produce research that improves the lives of all those affected by dementia.
The guideline offers clear, concise, and actionable recommendation statements to help clinicians to incorporate recommendations into clinical practice, with the goal of improving quality of care. Each recommendation is given a rating that reflects the level of confidence that potential benefits of an intervention outweigh potential harms.