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This important new book presents critical information on the clinical and morphological aspects of various endocrinological disorders of the gut and pancreas. Topics include a historical perspective and broad overview of the neuroendocrine component of the gut; hyperplastic proliferations of gastrointestinal endocrine cells; pancreatic endocrine cells and their non-neoplastic proliferations; tumors and lesions; and endocrine differentiation in nonendocrine tumors. The book stresses clinical and pathological aspects of these topics, as well as the pathogenesis, clinicopathological correlations, and diagnostic approaches. Gastroenterologists, pathologists, internists, surgeons, endocrinologists and others interested in endocrinological disorders of the gut and pancreas will discover that this book will be a welcome addition to your reference library.
This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all aspects of gastrointestinal pathology to help pathologists differentiate between closely related digestive tract disorders, this volume incorporates the most up-to-date scientific and technical knowledge, providing a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, the fourth edition of Diagnostic Pathology: Gastrointestinal is a visually stunning, one-stop resource for every practicing pathologist, fellow, resident, or student as an ideal day-to-day reference or as a reliable training resource, and is useful to even the most experienced pathologist for current details on the diagnosis and characterization of neoplastic and nonneoplastic diseases of the digestive tract. Covers all areas of gastrointestinal pathology-from esoteric topics like microsporidia to common issues like serrated colorectal polyps Includes important new material on recently discovered genetic alterations in GI cancers, targeted gene therapies, and the changed approach to GI endocrine neoplasms, as well as numerous new chapters on other timely issues, such as COVID-19's effects on the GI system, drug-induced GI diseases, and more Contains significantly updated information throughout, including new content, images, and references that reflect the most current diagnoses, provide ease for daily case sign-out, and contain details related to the latest WHO Classification of Tumours: Digestive System Tumours Features more than 2,600 print and online-only images, including histology and gross pathology images, full-color medical illustrations, clinical photographs, and radiology images to help practicing and in-training pathologists reach a confident diagnosis Employs consistently templated chapters, bulleted content, key facts, annotated images, and an extensive index for quick, expert reference at the point of care Includes an eBook version that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud; additional digital ancillary content may publish up to 6 weeks following the publication date . 10-15 new chapters plus image, text, and Reference updates across the book's 200 chapters are in place for the 4th ed. of DP: Gastrointestinal. New chapters are added, and existing contents are updated, to address the newest WHO Classification of Digestive System Tumors. The updated Classification includes a change to how appendiceal neoplasms are classified. Additional new content covers the changed overall approach to gastrointestinal endocrine neoplasms and how to differentiate Grade 3 endocrine tumors from high grade neuroendocrine carcinomas. New 4th ed chapters also include details on targeted gene therapies and important genes now identified which involve primary cancers of the GI tract.
Diagnostic Pathology of the Intestinal Mucosa - An Atlas and Review of Biopsy Interpretation offers a comprehensive overview of intestinal mucosal structure as defined through peroral or endoscopic biopsy specimens obtained in normal and disease states. It describes small intestinal biopsy pathology in conjunction with morphologic, functional, and pathophysiologic correlations. Routine methods of processing tissues for light microscopy, electron microscopy, histochemistry, and light- and electron- microscopic-immunoperoxidase techniques are presented so that the novice in the area of intestinal structure may have an easily accessible reference for setting up a morphologic laboratory.
A unique case-based molecular approach to understanding pathology Pathology: A Modern Case Study is a concise, focused text that emphasizes the molecular and cellular biology essential to understanding the concepts of disease causation. The book includes numerous case studies designed to highlight the role of the pathologist in the team that provides patient care. Pathology: A Modern Case Study examines the role of anatomic, clinical, and molecular pathologists in dedicated chapters and in descriptions of the pathology of specific organ systems. Features Coverage of pathology focuses on modern approaches to common and important diseases Each chapter delivers the most up-to-date advances in pathology Learning aids include chapter summaries and overviews, bolded terms, and a glossary Common clinically relevant disease are highlighted Disease discussion is based on organ compartment and etiology Coverage includes: Disease and the Genome: Genetic, Developmental and Neoplastic Disease Cell Injury, Death and Aging and the Body's Response Environmental Injury Clinical Practice: Anatomic Pathology Clinical Practice: Molecular Pathology Clinical Practice: Molecular Pathology Organ-specific pathology covering all major body systems Molecular pathology Essential for undergraduate medical students and clinicians who wish to expand their knowledge pathology, Pathology: A Modern Case Study delivers valuable coverage that is directly related to a patient’s condition and the clinical practice of pathology.
Diagnostic Pathology of the Intestinal Mucosa - An Atlas and Review of Biopsy Interpretation offers a comprehensive overview of intestinal mucosal structure as defined through peroral or endoscopic biopsy specimens obtained in normal and disease states. It describes small intestinal biopsy pathology in conjunction with morphologic, functional, and pathophysiologic correlations. Routine methods of processing tissues for light microscopy, electron microscopy, histochemistry, and light- and electron- microscopic-immunoperoxidase techniques are presented so that the novice in the area of intestinal structure may have an easily accessible reference for setting up a morphologic laboratory.
Visually stunning and easy to use, this volume in the highly regarded Diagnostic Pathology series covers the normal histology of every organ system. This edition incorporates the most recent scientific and technological knowledge in the field to provide a comprehensive overview of all areas of normal histology, including introductory chapters on electron microscopy, immunofluorescence, immunohistochemistry and histochemistry, the cell, and the basic organization of tissues. With nearly 1,800 outstanding images, this reference is an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. Unparalleled visual coverage with carefully annotated photomicrographs, spectacular gross images, electron micrographs, and medical illustrations Time-saving reference features include bulleted text, a variety of test data tables, key facts in each chapter, annotated images, and an extensive index Thoroughly updated content throughout, with all-new chapters on synovium and histologic artifacts, a thoroughly revised skeletal muscle chapter that now addresses normal histology in the setting of neuromuscular biopsy, and coverage of additional histologic variations that cause diagnostic confusion New content on immunohistochemistry; more image examples of newly recognized normal variations, mimics, and pitfalls; and expanded text in many sections for greater clarity and ease of reference
Part of the highly regarded Diagnostic Pathology series, this updated volume by Dr. Vania Nosé is a visually stunning, easy-to-use reference covering 125 of the most common endocrine pathology diagnoses. Outstanding images—more than 2,400 in all—make this an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. This second edition incorporates the most recent clinical, pathological, histological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Essential knowledge in all areas of endocrine pathology, including thyroid, parathyroid, pituitary, adrenal, pancreas, skin, and inherited tumor syndromes Unsurpassed visual coverage with more than 2,400 carefully annotated clinical images, gross pathology, histology, and special and immunohistochemical stains that provide clinically and diagnostically important information on typical and variant disease features Designed to help you identify crucial elements of each diagnosis along with associated differential diagnoses and pitfalls to more quickly resolve problems during routine sign out of cases Time-saving reference features include bulleted text, a variety of test data tables, key facts in each chapter, annotated images, and an extensive index Thoroughly updated content throughout, reflecting new WHO classifications for endocrine diseases, recently discovered and newly described endocrine disease entities and genetic causes, and treatment changes of endocrine diseases New coverage of encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC), with a new chapter on the new entity NIFTP, new genetic discoveries in the development of pheochromocytoma and paragangliomas, new names that demonstrate the differentiation of certain tumors, and new information on immunoglobulin G4-related disease (IgG4-RD) involving thyroid
With abundant at-a-glance tables, the volume reviews normal histology before examining abnormal findings, covers all of the most commonly seen neoplastic and non-neoplastic conditions of the endocrine system, and uses a consistent, user-friendly format to explore each entity's clinical features pathologic features (gross and microscopic) ancillary studies differential diagnoses and prognostic and therapeutic considerations. Heavily illustrated.