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Designed for use at the laboratory work bench, this practical manual provides an overview of the major components of the immune system and their functions, followed by step-by-step instructions for all major assays performed in a diagnostic immunology laboratory.
THE authoritative guide for clinical laboratory immunology For over 40 years the Manual of Molecular and Clinical Laboratory Immunology has served as the premier guide for the clinical immunology laboratory. From basic serology testing to the present wide range of molecular analyses, the Manual has reflected the exponential growth in the field of immunology over the past decades. This eighth edition reflects the latest advances and developments in the diagnosis and treatment of patients with infectious and immune-mediated disorders. The Manual features detailed descriptions of general and specific methodologies, placing special focus on the interpretation of laboratory findings, and covers the immunology of infectious diseases, including specific pathogens, as well as the full range of autoimmune and immunodeficiency diseases, cancer, and transplantation. Written to guide the laboratory director, the Manual will also appeal to other laboratory scientists, especially those working in clinical immunology laboratories, and pathologists. It is also a useful reference for physicians, mid-level providers, medical students, and allied health students with an interest in the role that immunology plays in the clinical laboratory.
This is the most comprehensive, up-to-date and one-volume guide to protocols in the immunology lab available anywhere. Carefully edited by two of the leading clinical and laboratory immunologists in the world, with concise chapters by 69 experts in their respective subspecialties, this book serves as both a useful reference and a practical manual of laboratory protocols. Published under the auspices of the Americal Medical Laboratory Immunologists, Clinical Diagnosis Immunology is designed to be useful in the day-to-day work of all medical laboratory professionals. It is an indispensable new tool for the modern medical lab, destined to become the standard reference/text in the field.
A two-in-one text providing teaching lab students with an overview of immunology as well as a lab manual complete with current standard exercises. Section I of this book provides an overview of the immune system and immunity, and includes review questions, problem sets, case studies, inquiry-based questions, and more to provide students with a strong foundation in the field. Section II consists of twenty-two lab exercises focused on key concepts in immunology, such as antibody production, cell separation, cell function, immunoassays, Th1/Th2 cytokine detection, cell and tissue culture methods, and cell and molecular biology techniques. Appendices include safety information, suggested links and readings, and standard discipline processes, protocols, and instructions.
This practical laboratory manual provides an essential source of reference, information and guidance for all laboratory and clinical immunologists. It fully describes the methods used in diagnostic immunopathology, and discusses the interpretation and value of the parameters measured. It also answers important practical questions: which parameters are useful in arriving at a diagnosis; which are useful for monitoring the severity of a disease; what level of precision is achievable, and what level is useful; how do we measure accuracy, and how do we achieve inter-laboratory consistency? Each chapter has a brief introduction which provides some general comments on the procedures involved. The methods section contains detailed descriptions with helpful notes on the advantages and disadvantages of different methods and potential pitfalls. Finally, each chapter concludes with a section on clinical applications, which discusses the interpretation, value and limitations of the information obtained, and asks what alternative interpretations should be considered, and what additional information is called for.
Reflects changes being thrust upon the laboratory community.
As enrollments in immunology courses continue to expand, so do the calls for up-to-date, professional lab manuals. "Immunology: A Laboratory Manual brings together a variety of methods that provide an experimental foundation for the study of immunology. Its wide range of experiments don't require sophisticated equipment or materials and can be tied easily to most immunology texts.