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This book reviews the current understanding of the mechanical, chemical and biological processes that are responsible for the degradation of a variety of implant materials. All 18 chapters will be written by internationally renowned experts to address both fundamental and practical aspects of research into the field. Different failure mechanisms such as corrosion, fatigue, and wear will be reviewed, together with experimental techniques for monitoring them, either in vitro or in vivo. Procedures for implant retrieval and analysis will be presented. A variety of biomaterials (stainless steels, titanium and its alloys, nitinol, magnesium alloys, polyethylene, biodegradable polymers, silicone gel, hydrogels, calcium phosphates) and medical devices (orthopedic and dental implants, stents, heart valves, breast implants) will be analyzed in detail. The book will serve as a broad reference source for graduate students and researchers studying biomedicine, corrosion, surface science, and electrochemistry.
Provides a comprehensive, yet practical source of reference, and excellent foundation for comparing the properties and performance of coatings and selecting the most suitable materials based on specific service needs and environmental factors. Coating technology has developed significant techniques for protecting existing infrastructure from corrosion and erosion, maintaining and enhancing the performance of equipment, and provided novel functions such as smart coatings greatly benefiting the medical device, energy, automotive and construction industries. The mechanisms, usage, and manipulation of cutting-edge coating methods are the focus of this book. Not only are the working mechanisms of coating materials explored in great detail, but also craft designs for further optimization of more uniform, safe, stable, and scalable coatings. A group of leading experts in different coating technologies demonstrate their main applications, identify the key bottlenecks, and outline future prospects. Advanced Coating Materials broadly covers the coating techniques, including cold spray, plasma vapor deposition, chemical vapor deposition, sol–gel method, etc., and their significant applications in microreactor technology, super(de)wetting, joint implants, electrocatalyst, etc. Numerous kinds of coating structures are addressed, including nanosize particles, biomimicry structures, metals and complexed materials, along with the environmental and human compatible biopolymers resulting from microbial activities. This state-of-the-art book is divided into three parts: (1) Materials and Methods: Design and Fabrication, (2) Coating Materials: Nanotechnology, and (3) Advanced Coating Technology and Applications.
This book presents select proceedings of the International Conference on Advanced Lightweight Materials and Structures (ICALMS) 2020, and discusses the triad of processing, structure, and various properties of lightweight materials. It provides a well-balanced insight into materials science and mechanics of both synthetic and natural composites. The book includes topics such as nano composites for lightweight structures, impact and failure of structures, biomechanics and biomedical engineering, nanotechnology and micro-engineering, tool design and manufacture for producing lightweight components, joining techniques for lightweight structures for similar and dissimilar materials, design for manufacturing, reliability and safety, robotics, automation and control, fatigue and fracture mechanics, and friction stir welding in lightweight sandwich structures. The book also discusses latest research in composite materials and their applications in the field of aerospace, construction, wind energy, automotive, electronics and so on. Given the range of topics covered, this book can be a useful resource for beginners, researchers and professionals interested in the wide ranging applications of lightweight structures.
The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine.This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials' community. - The most comprehensive coverage of principles and applications of all classes of biomaterials - Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials - Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. - Online chapter exercises available for most chapters
This book consists of peer-reviewed proceedings from the International Conference on Innovations in Mechanical Engineering (ICIME 2020). The contents cover latest research in all major areas of mechanical engineering, and are broadly divided into five parts: (i) thermal engineering, (ii) design and optimization, (iii) production and industrial engineering, (iv) materials science and metallurgy, and (v) multidisciplinary topics. Different aspects of designing, modeling, manufacturing, optimizing, and processing are discussed in the context of emerging applications. Given the range of topics covered, this book can be useful for students, researchers as well as professionals.
The biomaterials sector is rapidly expanding and significant advances have been made in the technology of biomedical coatings and materials, which provide a means to improve the wear of joints, change the biological interaction between implant and host and combine the properties of various materials to improve device performance. Coatings for biomedical applications provides an extensive review of coating types and surface modifications for biomedical applications.The first part of the book explores a range of coating types and their biomedical applications. Chapters look at hydrophilic, mineral and pyrolytic carbon coatings in and ex vivo orthopaedic applications and finally at surface modification and preparation techniques. Part two presents case studies of orthopaedic and ophthalmic coatings, and biomedical applications including vascular stents, cardiopulomonary by-pass equipment and ventricular assist devices.With its clear structure and comprehensive review of research, Coatings for biomedical applications is a valuable resource to researchers, scientists and engineers in the biomedical industry. It will also benefit anyone studying or working within the biomedical sector, particularly those specialising in biomedical coatings. - Provides an extensive review of coating types and surface modifications for biomedical applications - Chapters look at hydrophilic coatings for biomedical applications in and ex vivo, mineral coatings for orthopaedic applications, pyrolytic carbon coating and other commonly-used biomedical coatings - Presents case studies of orthopaedic and ophthalmic coatings, and biomedical applications including vascular stents, cardiopulomonary by-pass equipment and ventricular assist devices
This handbook describes several current trends in the development of bioceramics and biocomposites for clinical use in the repair, remodelling, and regeneration of bone tissue. Comprehensive coverage of these materials allows fundamental aspects of the science and engineering to be seen in close relation to the clinical performance of dental and orthopaedic implants. Bioceramics and biocomposites appear to be the most dynamic area of materials development for both tissue engineering and implantable medical devices. Almost all medical specialties will continue to benefit from these developments, but especially dentistry and orthopaedics. In this Handbook, leading researchers describe the use of bionanomaterials to create new functionalities when interfaced with biological molecules or structures. Also described are technologies for bioceramics and biocomposites processing in order to fabricate medical devices for clinical use. Another important section of the book is dedicated to tissue regeneration with development of new matrices. A targeted or personalized treatment device reduces drug consumption and treatment expenses, resulting in benefits to the patient and cost reductions for public health systems. This authoritative reference on the state-of-the-art in the development and use of bioceramics and biocomposites can also serve as the basis of instructional course lectures for audiences ranging from advanced undergraduate students to post-graduates in materials science and engineering and biomedical engineering.
This book provides readers with the fundamentals necessary for understanding thermal spray technology. Coverage includes in-depth discussions of various thermal spray processes, feedstock materials, particle-jet interactions, and associated yet very critical topics: diagnostics, current and emerging applications, surface science, and pre and post-treatment. This book will serve as an invaluable resource as a textbook for graduate courses in the field and as an exhaustive reference for professionals involved in thermal spray technology.
Well-known for their inability to heal, articular cartilage injuries often degenerate inexorably to disastrous impairment. Multitudes of treatments have been devised for this problem, but no satisfactory long-term solutions have been established. Written by world-class experts, Articular Cartilage covers the latest research and advancements related to biology, development, pathology, clinical applications, and tissue engineering. This book is useful for rheumatologists, orthopaedic surgeons, cartilage biologists, and cartilage engineers as well as for professionals working in the orthopaedic and other musculoskeletal industries. This book also belongs in the library of primary care physicians, gerontologists, physical therapists, kinesiologists, and chiropractors. Written at a level that allows accessibility to a wide audience, it provides an interdisciplinary approach that encompasses the breadth and depth of basic science, bioengineering, translational science, and detailed methodologic approaches. The authors examine the major events and signaling molecules that lead to development of articular cartilage from precursor cells, and the changes in cartilage as it matures and ages. They focus on the epidemiology, etiopathogenesis, and therapeutic approaches for cartilage injury and the major arthritides that affect cartilage and the synovial joints such as osteoarthritis, rheumatoid arthritis, and gout. They supply an up-to-date overview of the field of tissue engineering as applied to articular cartilage repair. They examine a number of methods used to assess structure, composition, biology, and biomechanical function. Each chapter contains extensive references to enhance additional study. The book’s comprehensive focus on multiple aspects of articular cartilage sets it apart from other tissue engineering or developmental biology-based books available. It includes important discussions and perspectives on many of the remaining challenges and opportunities in the development and translation of new approaches for treating diseases of articular cartilage. It also provides detailed working protocols for many of the methods used to study articular cartilage, coverage of current treatment options, and business and regulatory aspects of the development of cartilage products. It provides a deeper understanding that will help with the development of new products and clinical applications.