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Anhand verschiedener Beispiele zeigen die Autoren die Bedeutung der Kristallographie für Chemie und Biochemie auf und bieten somit eine gute Zusammenfassung der allgemeinen Prinzipien der Kristallstrukturanalyse. Zum einen sollen Interessierte, die diese Methode nicht selbst durchführen, in die Lage versetzt werden, deren Ergebnisse zu interpretieren. Zum anderen wird dem Leser deutlich gemacht, welche Bedeutung die ungeheure Datenmenge, die sich aus dieser Methode ergibt, einerseits für die Chemie sowie andererseits für die Biochemie hat. Das Buch ist verständlich geschrieben und mit zahlreichen Abbildungen versehen. Durch die Darstellung der Kristallstrukturanalyse im Vergleich zu anderen Methoden ist das Werk auch besonders für fortgeschrittene Studenten geeignet, die sich mit der Kristallographie vertraut machen wollen.
The purpose of this book is to explain why molecular structure can be determined by single-crystal diffraction of X rays. It is not an account of the practical procedural details, but rather an account of the underlying physical principles, and the kinds of experiments and methods of handling the experimental data that are used.
A comprehensive examination of American women scientists across the sciences throughout the 20th century, providing a rich historical context for understanding their achievements and the way they changed the practice of science. Much more than a "Who's Who," this exhaustive two-volume encyclopedia examines the significant achievements of 20th century American women across the sciences in light of the historical and cultural factors that affected their education, employment, and research opportunities. With coverage that includes a number of scientists working today, the encyclopedia shows just how much the sciences have evolved as a professional option for women, from the dawn of the 20th century to the present. American Women of Science since 1900 focuses on 500 of the 20th century's most notable American women scientists—many overlooked, undervalued, or simply not well known. In addition, it offers individual features on 50 different scientific disciplines (Women in Astronomy, etc.), as well as essays on balancing career and family, girls and science education, and other sociocultural topics. Readers will encounter some extraordinary scientific minds at work, getting a sense of the obstacles they faced as the scientific community faced the questions of feminism and gender confronting the nation as a whole.
This book is designed to develop important practical skills for chemistry majors interested in synthetic chemistry. It will serve to teach students proper techniques for the preparation and handling of a variety of inorganic and coordination compounds. It shows them how to conduct thermal decomposition reactions; prepare moderately air-sensitive and moisture-sensitive compounds; and characterise obtained metal complexes using a variety of physical methods. This volume is well-illustrated with colour photos, schemes and figures that allow safe, step-by-step work on assigned laboratory experiments. There are extensive pre-lab instructions for techniques, concepts and topics of experiments, and complete initial introductions to the methods used during the lab are also provided. Because of its clearly presented content with numerous practical examples, this book will be of great interest to chemistry professionals working in industry.
Concise Encyclopaedia of Bioinformatics and Computational Biology, 2nd Edition is a fully revised and updated version of this acclaimed resource. The book provides definitions and often explanations of over 1000 words, phrases and concepts relating to this fast-moving and exciting field, offering a convenient, one-stop summary of the core knowledge in the area. This second edition is an invaluable resource for students, researchers and academics.
Crystal growth is the key step of a great number of very important applications. The development of new devices and products, from the traditional microelectronic industry to pharmaceutical industry and many others, depends on crystallization processes. The objective of this book is not to cover all areas of crystal growth but just present, as specified in the title, important selected topics, as applied to organic and inorganic systems. All authors have been selected for being key researchers in their field of specialization, working in important universities and research labs around the world. The first section is mainly devoted to biological systems and covers topics like proteins, bone and ice crystallization. The second section brings some applications to inorganic systems and describes more general growth techniques like chemical vapor crystallization and electrodeposition. This book is mostly recommended for students working in the field of crystal growth and for scientists and engineers in the fields of crystalline materials, crystal engineering and the industrial applications of crystallization processes.
This volume contains the contributions of the keynote speakers to the BIOMAT 2005 symposium, as well as a collection of selected papers by pioneering researchers. It provides a comprehensive review of the mathematical modeling of cancer development, Alzheimer's disease, malaria, and aneurysm development. Various models for the immune system and epidemiological issues are analyzed and reviewed. The book also explores protein structure prediction by optimization and combinatorial techniques (Steiner trees). The coverage includes bioinformatics issues, regulation of gene expression, evolution, development, DNA and array modeling, and small world networks.
Crystallography Made Crystal Clear makes crystallography accessible to readers who have no prior knowledge of the field or its mathematical basis. This is the most comprehensive and concise reference for beginning Macromolecular crystallographers, written by a leading expert in the field. Rhodes' uses visual and geometric models to help readers understand the mathematics that form the basis of x-ray crystallography. He has invested a great deal of time and effort on World Wide Web tools for users of models, including beginning-level tutorials in molecular modeling on personal computers. Rhodes' personal CMCC Home Page also provides access to tools and links to resources discussed in the text. Most significantly, the final chapter introduces the reader to macromolecular modeling on personal computers-featuring SwissPdbViewer, a free, powerful modeling program now available for PC, Power Macintosh, and Unix computers. This updated and expanded new edition uses attractive four-color art, web tool access for further study, and concise language to explain the basis of X-ray crystallography, increasingly vital in today's research labs. - Helps readers to understand where models come from, so they don't use them blindly andinappropriately - Provides many visual and geometric models for understanding a largely mathematical method - Allows readers to judge whether recently published models are of sufficiently high quality and detail to be useful in their own work - Allows readers to study macromolecular structure independently and in an open-ended fashion on their own computers, without being limited to textbook or journals illustrations - Provides access to web tools in a format that will not go out of date. Links will be updated and added as existing resources change location or are added
An assessment of the known properties of natural products and their model compounds to determine their usefulness in biological and medical experimentation, as well as in synkinetics - the reversible synthesis of noncovalent compounds. It explores new techniques such as cryoelectron and scanning force microscopy and solid-state NMR spectroscopy of