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SECTION 1: Airway Management -- Current Controversies 1. Can Sellick Maneuver Prevent Pulmonary Aspiration in the Critically Ill? 2. Etomidate vs. Ketamine -- What Should We Use for Intubation in ICU SECTION 2: Extracorporeal Therapies 3. Plasmapheresis: Current Indications in the Critically Ill 4. Are Super High-Flux Membrane Dialyzers the Future of RRT? 5. What is New in Artificial Liver Support Systems? SECTION 3: Sepsis 6. Back to the Genes: Does Genetic Polymorphism have a Role in Sepsis Management? 7. Controversies in Surviving Sepsis Guidelines 2021 8. Are We Back to Square One? Early Fluids vs. Vasopreressors in Septic Shock 9. Have We Achieved Balance in Fluid Therapy: Balanced Salt Solutions vs. Normal Saline? SECTION 4: Biomarkers 10. Novel Biomarkers During Circulatory Shock 11. Biomarkers in Acute Intoxications 12. Do Biomarkers have a Role in Patients with Primary Brain Injury? 13. Utility of MicroRNAs in the Critically Ill 14. Neutrophil to Lymphocyte Ratio in Critically Ill: A Simple but Useful Marker? 15. Do Vocal Biomarkers have a Future in Critical Care SECTION 5: COVID-19 Pandemic: Lessons Learnt 16. Awake Prone Positioning in ARDS? 17. Immunomodulators for COVID-19 Therapy 18. Has Critical Care Telemedicine Come of Age During the Pandemic 19. Post-COVID Conditions (PCCs) or Long COVID Syndrome 20. Capacity Building During Large Scale Disasters 21. Clearing the Air: Alternatives to Isolation Rooms SECTION 6: Mechanical Ventilation 22. Revisiting Exogenous Surfactant Therapy in Acute Lung Injury and ARDS 23. Mechanical Power 24. Volumetric Capnography in 2022 25. Metabolic Alkalosis in Critical Care: A Classical and Physicochemical Approach 26. Oxygen Revisited SECTION 7 28. High-flow Nasal Cannula: Beyond a COVID-19 Therapy 29. Cefiderocol 30. Newer Fluoroquinolones: Levonadifloxacin, Delafloxacin and Lascufloxacin 31. Newer Combinations of B-Lactam/B-Lactamase 32. Newer Tetracyclines -- Eravacycline and Omadacycline 33. Plazomicin: A New Aminoglycoside 34. Lefamulin: A Pleuromutilin Antibiotic 35. Pretomanid for Antitubercular Therapy 36. Contezolid Acefosamil: A New Oxazolidinone 37. Solithromycin and Nafithromycin: The New Macrolides 38. Benapenem and Sulopenem 39. The Dsb (Disulfide bond) 40. Antivirulence Strategies: The Future of Antibacterial Therapy 41. Alternatives to Conventional Antibacterials: Use of Nanomaterials 42. Newer Treatment Approach to Clostridioides Difficile - Fidaxomicin and Bezlotoxumab 43. Recent Advances for Immunotherapies Against Infectious Disease SECTION 8: What's New Elsewhere? 44. Risk Scoring Systems in Upper Gastrointestinal Bleed 45. Has Hypotension Prediction Index Come of Age 46. Postintensive Care Syndrome and Postintensive Care Syndrome-Family 47. Closed-Loop Hemodynamic Resuscitation In Shock 48. Is Electrical Impedance Tomography Finally Here to Stay 49. Cardiac Output Measurement: Capnodynamic Method and Auto VTI Tool 50. What's New in Glucose Management Technologies for the Critically-ill 51. Vitamins and Trace Element Supplementation for Critically Ill Patients in 2022 Index
This title presents key studies that have shaped the practice of critical care medicine. Selected using a rigorous methodology, the studies cover topics including: sedation and analgesia, resuscitation, shock, ARDS, nutrition, renal failure, trauma, infection, diabetes, and physical therapy
The COVID-19 pandemic is only the latest prompt about the importance of international health and its broad influence upon social wellbeing. The COVID-19 pandemic has highlighted the need for an informed and coordinated effort to achieve international healthcare equity. Leaders in international health must be conversant in its issues. Contemporary Issues in Global Medicine and Moving Toward International Healthcare Equity provides an understanding of contemporary issues in international medicine. It explores the impact of civil unrest on population health and provides practical strategies for providing clinical care in low resource settings. Covering topics such as international public health, maternal health, and drug resistance, this book is an essential resource for government officials, medical officials, physicians, nurses, social workers, sociologists, epidemiologists, medical students, students and educators of higher education, researchers, and academicians.
Pneumonia is an inflammatory disease of the air sacs and surrounding interstitium caused by infectious agents or by endogenous inflammatory tissue disorder termed interstitial pneumonia. The present book covers contemporary topics of community, hospital, and health care-related bacterial and viral pneumonia in the setting of drug resistance, environmental exposures, climate change, hormonal influences, and gender. The topic of interstitial pneumonia is brought under the lens of an immune-related connective tissue disease.
Cardiovascular disease is currently the leading cause of death of pregnant and postpartum women in the United States. Pregnancy can exacerbate known cardiovascular disorders and unmask previously unrecognized problems. The field of cardio-obstetrics is emerging and a clear area of need for improved quality of care. This book is the first authoritative and comprehensive volume dedicated to contemporary and practical topics in Cardio Obstetrics. It provides an up-to-date and highly illustrated synopsis of the pathophysiological, biomolecular, genetic, imaging features, translational and clinical applications of cardiometabolic disease, adverse pregnancy outcomes, cardiomyopathy, ischemic heart disease, maternal shock and structural heart disease in pregnancy and their role in maternal and fetal outcomes. It relays to the reader a contemporary view of the emerging interplay between the pregnancy and cardiovascular disease and risk factors and focuses on the pathophysiology, obstetrical and cardiac management of complex disorders in pregnancy. In addition, this volume discusses the clinical implications and therapeutic targets of a wide range of diseases in pregnancy from the preventive cardiology to critical care and advanced heart failure. Contemporary Topics in Cardio-Obstetrics is an essential resource for physicians, residents, fellows, and medical students in cardiology, endocrinology, primary care, and health promotion and disease prevention.
As healthcare systems continue to evolve, it is clear that providing safe, high-quality care to patients is an extremely complex process. Ranging from multi-disciplinary teams to bedside care, virtually every aspect of the patient-care experience provides us with an opportunity for doing things better, from improving efficiency, safety, and overall outcomes to reducing costs and promoting team synergy. This book, the fifth in our patient safety series collection, consists of chapters that help explore key concepts related to both the safety and quality of care. In a departure from the vignette-driven format of our earlier books, this installment gravitates toward discussing frameworks, theoretical considerations, team-centric approaches, and a variety of other concepts that are critical to both our understanding and the implementation of safer and better-performing health systems. We also feel that the knowledge presented herein increasingly applies across the world, especially as global health systems evolve and mature over time. It is our goal to improve the recognition of potential opportunities that will highlight various aspects of the delivery of healthcare and thus contribute to better patient experiences, with safety at the forefront. Topics covered in this volume, as well as the previous volumes, highlight the critical importance of identifying and addressing opportunities for improvement, not as one-time events, but rather as continuous, hardwired institutional processes.
Graduate medical education (GME) is a continually evolving, highly dynamic area within the complex fabric of the modern health-care environment. Given the rapidly changing regulatory, financial, scientific and technical aspects of GME, many institutions and programs face daily challenges of "keeping up" with the most recent developments within this ever-more-sophisticated operational environment. Organizational excellence is a requirement for the seamless functioning of GME programs, especially when one consider the multiple disciplines and stakeholders involved. The goal of the current book cycle, titled Contemporary Topics in Graduate Medical Education, beginning with this inaugural tome, is to provide GME professionals with a practical and readily applicable set of reference materials. More than 20 distinguished authors from some of the top teaching institutions in the US, touch upon some of the most relevant, contemporary, and at times controversial topics, including provider burnout, gender equality issues, trainee wellness, scholarly activities and requirements, and many other theoretical and practical considerations. We hope that the reader will find this book to be a valuable and high quality resource of a broad range of GME-related topics. It is the Editors' goal to create a multi-tome platform that will become the definitive go-to reference for professionals navigating the complex landscape of modern graduate medical education.
This is the premier evidence-based textbook in critical care medicine. The Third Edition features updated and revised chapters, numerous new references, streamlined content, and new chapters on key topics such as the new paradigm in critical care medicine, cardiac output monitoring, surgical optimization, vital signs, and arterial blood gas analysis. The book maintains the author’s trademark humor and engaging writing style and is suitable for a broad and diverse audience of medical students, residents, fellows, physicians, nurses, and respiratory therapists who seek the latest and best evidence in critical care. From reviews of previous editions: “This is an excellent introduction to the concept of evidence-based medicine...The writing is clear, logical, and highly organized, which makes for fast and enjoyable reading. I believe this book will get daily use in most intensive care units, by a wide range of readers.” –Respiratory Care “This is one of the most comprehensive handbooks on critical care medicine with a strong emphasis on evidence base...Overall, this book should be useful for junior doctors or intensive care trainees who are starting their term in an intensive care unit.” –Anaesthesia and Intensive Care
Knowledge of intensive care medicine is growing logarithmically. In addition, intensive care units and their number of beds are increasing in hospitals. Nowadays, the average human life is prolonged due to the growth of medical knowledge and skills. Intensive care units, both as a cause and as a consequence of long-life expectancy, are increasingly important. This book contains current topics on intensive care such as critical care for neonatal, neurological, and cardiological patients; fluid management in these patients; and intensive care infections. We wish the readers find this book to be helpful.