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A comprehensive Introduction to the world of brain and behavior computational models This book provides a broad collection of articles covering different aspects of computational modeling efforts in psychology and neuroscience. Specifically, it discusses models that span different brain regions (hippocampus, amygdala, basal ganglia, visual cortex), different species (humans, rats, fruit flies), and different modeling methods (neural network, Bayesian, reinforcement learning, data fitting, and Hodgkin-Huxley models, among others). Computational Models of Brain and Behavior is divided into four sections: (a) Models of brain disorders; (b) Neural models of behavioral processes; (c) Models of neural processes, brain regions and neurotransmitters, and (d) Neural modeling approaches. It provides in-depth coverage of models of psychiatric disorders, including depression, posttraumatic stress disorder (PTSD), schizophrenia, and dyslexia; models of neurological disorders, including Alzheimer’s disease, Parkinson’s disease, and epilepsy; early sensory and perceptual processes; models of olfaction; higher/systems level models and low-level models; Pavlovian and instrumental conditioning; linking information theory to neurobiology; and more. Covers computational approximations to intellectual disability in down syndrome Discusses computational models of pharmacological and immunological treatment in Alzheimer's disease Examines neural circuit models of serotonergic system (from microcircuits to cognition) Educates on information theory, memory, prediction, and timing in associative learning Computational Models of Brain and Behavior is written for advanced undergraduate, Master's and PhD-level students—as well as researchers involved in computational neuroscience modeling research.
This book presents an integrated framework for developing and testing computational models in psychology and related disciplines. Researchers and students are given the knowledge and tools to interpret models published in their area, as well as to develop, fit, and test their own models.
"This book argues that computational models in behavioral neuroscience must be taken with caution, and advocates for the study of mathematical models of existing theories as complementary to neuro-psychological models and computational models"--
A guide to computational modeling methods in neuroscience, covering a range of modeling scales from molecular reactions to large neural networks. This book offers an introduction to current methods in computational modeling in neuroscience. The book describes realistic modeling methods at levels of complexity ranging from molecular interactions to large neural networks. A “how to” book rather than an analytical account, it focuses on the presentation of methodological approaches, including the selection of the appropriate method and its potential pitfalls. It is intended for experimental neuroscientists and graduate students who have little formal training in mathematical methods, but it will also be useful for scientists with theoretical backgrounds who want to start using data-driven modeling methods. The mathematics needed are kept to an introductory level; the first chapter explains the mathematical methods the reader needs to master to understand the rest of the book. The chapters are written by scientists who have successfully integrated data-driven modeling with experimental work, so all of the material is accessible to experimentalists. The chapters offer comprehensive coverage with little overlap and extensive cross-references, moving from basic building blocks to more complex applications. Contributors Pablo Achard, Haroon Anwar, Upinder S. Bhalla, Michiel Berends, Nicolas Brunel, Ronald L. Calabrese, Brenda Claiborne, Hugo Cornelis, Erik De Schutter, Alain Destexhe, Bard Ermentrout, Kristen Harris, Sean Hill, John R. Huguenard, William R. Holmes, Gwen Jacobs, Gwendal LeMasson, Henry Markram, Reinoud Maex, Astrid A. Prinz, Imad Riachi, John Rinzel, Arnd Roth, Felix Schürmann, Werner Van Geit, Mark C. W. van Rossum, Stefan Wils
This text provides an introduction to computational aspects of early vision, in particular, color, stereo, and visual navigation. It integrates approaches from psychophysics and quantitative neurobiology, as well as theories and algorithms from machine vision and photogrammetry. When presenting mathematical material, it uses detailed verbal descriptions and illustrations to clarify complex points. The text is suitable for upper-level students in neuroscience, biology, and psychology who have basic mathematical skills and are interested in studying the mathematical modeling of perception.
Classically, behavioural neuroscience theorizes about experimental evidence in a qualitative way. However, more recently there has been an increasing development of mathematical and computational models of experimental results, and in general these models are more clearly defined and more detailed than their qualitative counter parts. These new computational models can be set up so that they are consistent with both single neuron and whole-system levels of operation, allowing physiological results to be meshed with behavioural data – thus closing the gap between neurophysiology and human behaviour. There is considerable diversity between models with respect to the methodology of designing a model, the degree to which neurophysiological processes are taken into account and the way data (behavioural, electrophysiological, etc) constrains a model. This book presents examples of this diversity and in doing so represents the state-of-art in the field through a unique collection of papers from the world's leading researchers in the area of computational modelling in behavioural neuroscience. Based on talks given at the third Behavioural Brain Sciences Symposium, held at the Behavioural Brain Sciences Centre, University of Birmingham, in May 2007, the book appeals to a broad audience, from postgraduate students beginning to work in the field to experienced experimenters interested in an overview.
This text, based on a course taught by Randall O'Reilly and Yuko Munakata over the past several years, provides an in-depth introduction to the main ideas in the computational cognitive neuroscience. The goal of computational cognitive neuroscience is to understand how the brain embodies the mind by using biologically based computational models comprising networks of neuronlike units. This text, based on a course taught by Randall O'Reilly and Yuko Munakata over the past several years, provides an in-depth introduction to the main ideas in the field. The neural units in the simulations use equations based directly on the ion channels that govern the behavior of real neurons, and the neural networks incorporate anatomical and physiological properties of the neocortex. Thus the text provides the student with knowledge of the basic biology of the brain as well as the computational skills needed to simulate large-scale cognitive phenomena. The text consists of two parts. The first part covers basic neural computation mechanisms: individual neurons, neural networks, and learning mechanisms. The second part covers large-scale brain area organization and cognitive phenomena: perception and attention, memory, language, and higher-level cognition. The second part is relatively self-contained and can be used separately for mechanistically oriented cognitive neuroscience courses. Integrated throughout the text are more than forty different simulation models, many of them full-scale research-grade models, with friendly interfaces and accompanying exercises. The simulation software (PDP++, available for all major platforms) and simulations can be downloaded free of charge from the Web. Exercise solutions are available, and the text includes full information on the software.
Learn to use computational modelling techniques to understand the nervous system at all levels, from ion channels to networks.
Provides an introduction to the neural network modeling of complex cognitive and neuropsychological processes. Over the past few years, computer modeling has become more prevalent in the clinical sciences as an alternative to traditional symbol-processing models. This book provides an introduction to the neural network modeling of complex cognitive and neuropsychological processes. It is intended to make the neural network approach accessible to practicing neuropsychologists, psychologists, neurologists, and psychiatrists. It will also be a useful resource for computer scientists, mathematicians, and interdisciplinary cognitive neuroscientists. The editors (in their introduction) and contributors explain the basic concepts behind modeling and avoid the use of high-level mathematics. The book is divided into four parts. Part I provides an extensive but basic overview of neural network modeling, including its history, present, and future trends. It also includes chapters on attention, memory, and primate studies. Part II discusses neural network models of behavioral states such as alcohol dependence, learned helplessness, depression, and waking and sleeping. Part III presents neural network models of neuropsychological tests such as the Wisconsin Card Sorting Task, the Tower of Hanoi, and the Stroop Test. Finally, part IV describes the application of neural network models to dementia: models of acetycholine and memory, verbal fluency, Parkinsons disease, and Alzheimer's disease. Contributors J. Wesson Ashford, Rajendra D. Badgaiyan, Jean P. Banquet, Yves Burnod, Nelson Butters, John Cardoso, Agnes S. Chan, Jean-Pierre Changeux, Kerry L. Coburn, Jonathan D. Cohen, Laurent Cohen, Jose L. Contreras-Vidal, Antonio R. Damasio, Hanna Damasio, Stanislas Dehaene, Martha J. Farah, Joaquin M. Fuster, Philippe Gaussier, Angelika Gissler, Dylan G. Harwood, Michael E. Hasselmo, J, Allan Hobson, Sam Leven, Daniel S. Levine, Debra L. Long, Roderick K. Mahurin, Raymond L. Ownby, Randolph W. Parks, Michael I. Posner, David P. Salmon, David Servan-Schreiber, Chantal E. Stern, Jeffrey P. Sutton, Lynette J. Tippett, Daniel Tranel, Bradley Wyble
Trains researchers and graduate students in state-of-the-art statistical and machine learning methods to build models with real-world data.