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This atlas offers stunning color electron scanning micrographs and exceptional light microscopy pictures of capillaries, vessels and diverse histomorphological tissues and organs of Xenopus laevis. The model organisms Xenopus laevis serves to study basic biological questions related to growth, differentiation, maturation, and regression of cells, tissues and organs. Xenopus and human genomes have long stretches of gene collinearity, and 79% of identified human disease genes have a verified ortholog in Xenopus. Thus, this atlas will be a powerful tool for anatomists, morphologists, histologists and physiologists interested in normal and pathologically altered organs and tissue; and to all researchers, who wish to learn more about the microvascular anatomy of this vertebrate model organism.
The Color Atlas of "Xenopus laevis" Histology provides the first central source on the microscopic anatomy of cells, tissues, and major organs of the adult South African clawed frog, Xenopus laevis. For many years, X. laevis has been a highly popular experimental animal model in many areas of research. The recent development of transgenic Xenopus technology offers the promise that this animal model will be utilized more than ever before. The purpose of this book is to provide the active researcher with a central source of high quality light microscopic color images of the tissues of X. laevis, to aid in the identification of the cells and tissues of interest.
Now in its third edition, Veterinary Hematology: Atlas of Common Domestic and Non-Domestic Species continues to offer veterinarians and veterinary technicians an essential guide to veterinary hematology. Comprehensive in scope, the atlas presents the fundamentals of both normal and abnormal blood cell morphologies, with coverage of a wide range of species, including dogs, cats, horses, ruminants, llamas, rats, mice, nonhuman primates, ferrets, rabbits, guinea pigs, birds, amphibians, and reptiles. Designed as a useful and accessible guide, the updated third edition presents more than 300 color images and includes a new chapter that describes the best techniques for using hematology instruments. The authors—noted experts on the topic—clearly show how to identify and interpret the hematological changes that may occur in a variety of species. In addition, a companion website offers a wealth of additional hematological images. This vital atlas: Provides an updated edition of the popular veterinary hematology atlas for veterinarians, veterinary students, and veterinary technicians Contains a new instructive chapter on hematology instrumentation Presents hundreds of high-quality color photographs that help in identification Covers a range of species from dogs and cats to birds and reptiles Features a companion website that provides a wealth of hematological images Written for both novice and experienced veterinarians, Veterinary Hematology provides a complete resource to blood morphologic abnormalities in domestic and non-domestic species.
Annotation Explains techniques for microinjecting foreign genes into transgenic embryos of frogs and the information such research can provide about the role and spatiotemporal regulation of nervous system proteins during vertebrate development. Explains the basic scientific background and protocols, development, in vitro fertilization and microinjection, and a variety of biochemical and histochemical techniques for analyzing the results of the experiment. Also presents extensive data gathered by the approach. Annotation c. by Book News, Inc., Portland, Or.
Xenopus have gained increasing popularity as a laboratory animal and continue to serve as an important part of biomedical research. This book offers a practical reference to the care and maintenance of captive clawed frogs. With full-color illustrations of management practices and technical procedures, the text explores the wide range of responsibilities facing individuals who work with this species, from husbandry, compliance, and veterinary care to housing and water quality management. Numerous figures and tables enhance understanding of concepts. An experienced researcher at a top tier institution, the author provides an invaluable guide for facility technicians and animal caretakers.
The eye is a complex sensory organ, which enables visual perception of the world. Thus the eye has several tissues that do different tasks. One of the most basic aspects of eye function is the sensitivity of cells to light and its transduction though the optic nerve to the brain. Different organisms use different ways to achieve these tasks. In this sense, eye function becomes a very important evolutionary aspect as well. This book presents the different animal models that are commonly used for eye research and their uniqueness in evaluating different aspects of eye development, evolution, physiology and disease. - Presents information on the major animal models used in eye research including invertebrates and vertebrates - Provides researchers with information needed to choose between model organisms - Includes an introductory chapter on the different types of eyes, stressing possible common molecular machinery
Haschek and Rousseaux's Handbook of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. The 3e has been expanded by a full volume, and covers aspects of safety assessment not discussed in the 2e. Completely revised with many new chapters, it remains the most authoritative reference on toxicologic pathology for scientists and researchers studying and making decisions on drugs, biologics, medical devices and other chemicals, including agrochemicals and environmental contaminants. New topics include safety assessment, the drug life cycle, risk assessment, communication and management, carcinogenicity assessment, pharmacology and pharmacokinetics, biomarkers in toxicologic pathology, quality assurance, peer review, agrochemicals, nanotechnology, food and toxicologic pathology, the environment and toxicologic pathology and more. - Provides new chapters and in-depth discussion of timely topics in the area of toxicologic pathology and broadens the scope of the audience to include toxicologists and pathologists working in a variety of settings - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features hundreds of full color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations
Haschek and Rousseaux's Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to four separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, Volume 1, "Principles and the Practice of Toxicologic Pathology," covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Other volumes in this work round out the depth and breadth of coverage.Volume 2 encompasses "Toxicologic Pathology in Safety Assessment" and "Environmental Toxicologic Pathology". These two sections cover the application of toxicologic pathology in developing specific product classes, principles of data interpretation for safety assessment, and toxicologic pathology of major classes of environmental toxicants. Volumes 3 and 4 provide deep and broad treatment of "Target Organ Toxicity", emphasizing the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. These volumes comprise the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately. - Provides new chapters on digital pathology, juvenile pathology, in vitro/in vivo correlation, big data technologies and in-depth discussion of timely topics in the area of toxicologic pathology - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features hundreds of full-color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations
The newly revised Fifth Edition of Exotic Animal Hematology and Cytology delivers a fully updated new edition of the most complete reference to hematology and cytology in exotic animals. The book features high-quality images and step-by-step descriptions of practical techniques. Organized by animal class to make it easier to quickly find critical information, the authors have included 45 new case studies to highlight the application of the content in a real-world setting. All major exotic animal groups are covered, including mammals, birds, reptiles, amphibians, and fish. Clinicians seeking a decision-making aid for patient workup, treatment, and prognosis will find what they need in Exotic Animal Hematology and Cytology. The book also includes: Thorough cellular descriptions unique to mammalian, avian, herptile, and fish species, with extensive discussions of blood and bone marrow sample collection and hematologic techniques for each group Comprehensive evaluation of the peripheral blood specific to mammals, birds, herptiles, and fish, as well as the evaluation of bone marrow Practical discussions of hematology case studies with applications to common real-world clinical problems Color atlas of hemic cells of select species for quick and easy reference Extensive examinations of cytodiagnosis and exploration of unique features within mammals, birds, herptiles, and fish, as well as cytology case studies and wet-mount cases in fish Access to video clips and additional case reports on a companion website Exotic Animal Hematology and Cytology is an essential reference for veterinary clinical pathologists, anatomic pathologists, clinicians, and technicians, as well as for veterinary students taking courses involving exotic hematology and cytology.