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Over fifty years have passed since the first patient was treated with fast neutrons, but this form of therapy is still a matter of bitter dispute. Neutron generators have been installed in many countries and now patients can be treated with equipment that is technically similar to modern megavoltage x-ray equipment. The Physics and Radiobiology of Fast Neutron Beams presents a full discussion of the physical and radiobiological factors governing the production and use of fast neutron beams for therapy. The book discusses vastly improved neutron generators, advances in the standardization of dosimetric methods, and the specification of radiation quality. In addition, it explores nuclear methods of analysis, particularly neutron activation analysis in vivo. Influencing the place of radiotherapy with neutrons and other heavy particles, the radiobiological factors governing the treatment of cancer with radiation are examined. The author also studies the radiation hazard of neutrons, a matter of importance in the use of neutrons for chemical analysis in vivo. The Physics and Radiobiology of Fast Neutron Beams will be a valuable introduction to the subject for radiotherapists, medical physicists, radiographers, and radiobiologists new to the field. The book is also a useful summary of current knowledge for those already established in the use of fast neutrons for medical purposes.
The need for this book arose from my teaching, engineering, and - search experience in the non-power aspects of nuclear technology. The lack of a comprehensive textbook in industrial applications of radiation frustrated my students, who had to resort to a multitude of textbooks and research publications to familiarize themselves with the fundam- tal and practical aspects of radiation technology. As an engineer, I had to acquire the design aspects of radiation devices by trial-and-error, and often by accidental reading of a precious publication. As a researcher and a supervisor of graduate students, I found that the needed literature was either hard to find, or too scattered and diverse. More than once, I discovered that what appeared to be an exciting new idea was an old concept that was tried a few decades earlier during the golden era of “Atom for Peace”. I am hoping, therefore, that this book will serve as a single comprehensive reference source in a growing field that I expect will continue to expand. This book is directed to both neophytes and experts, and is written to combine the old and the new, the basic and the advanced, the simple and the complex. It is anticipated that this book will be of help in - viving older concepts, improving and expanding existing techniques and promoting the development of new ones.
The fifth edition of this respected book encompasses all the advances and changes that have been made since it was last revised. It not only presents new ideas and information, it shifts its emphases to accurately reflect the inevitably changing perspectives in the field engendered by progress in the understanding of radiological physics. The rapid development of computing technology in the three decades since the publication of the fourth edition has enabled the equally rapid expansion of radiology, radiation oncology, nuclear medicine and radiobiology. The understanding of these clinical disciplines is dependent on an appreciation of the underlying physics. The basic radiation physics of relevance to clinical oncology, radiology and nuclear medicine has undergone little change over the last 70 years, so much of the material in the introductory chapters retains the essential flavour of the fourth edition, updated as required. This book is written to help the practitioners in these fields understand the physical science, as well as to serve as a basic tool for physics students who intend working as medical radiation physicists in these clinical fields. It is the authors’ hope that students and practitioners alike will find the fifth edition of The Physics of Radiology lucid and straightforward.
Fast neutron therapy was introduced in London in 1970. The book gives an overview of the developments of the past 28 years, assesses the results of fast neutron treatment, and reviews the compiled clinical data worldwide. The authors describe the radiobiological profile of the neutron beams and evaluate the neutron RBE for secondary cancer induction, they introduce heavy-ion therapy, which combines high physical selectivity with the biological advantages of high-LET radiation for some tumor types, and finally they describe the very recent developments in Boron Neutron Capture Therapy (BNCT).
This book provides a comprehensive and up-to-date introduction to the fundamental theory and applications of slow-neutron scattering.