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Data obtained by population based cancer registries have a pivotal role in cancer control. Now also available in Spanish and French, this volume, which contains 15 authored chapters and four useful appendices, remains a standard reference for those planning to establish new cancer registries and those keen to adopt recognized methodologies. Information is given on the techniques required to collect, store, analyse and interpret data.
Navigating the tumultuous waters of cancer treatment and decision making is difficult for all patients. It is also difficult for doctors and other medical personnel. This books deals with a variety of emotion-related and ethics issues that form much of the basis of the world of cancer related medicine: the responsibilities of the physician relative to truth, full disclosure, patient autonomy, death and dying, physician assisted suicide, and suicide in general among cancer patients. These and many other matters are discussed using real stories from the author’s extensive personal career in working with cancer patients and their families. This is not a book on treating cancer, but instead is a work that seeks to stimulate a dialog about these issues as well as the spiritual aspects of hope and other factors relating to the plight of cancer patients and their families. Written for health care professionals and cancer victims and their families alike, the core of the book centers around questions of medical ethics, doctor-patient relationships, decision making during cancer treatment (from medical and patient points of view). Given the emotional commitment and energy level required to work with cancer patients in a moral and ethical manner, medical students and residents will ask themselves: do I really want to be a cancer physician? Can I handle the ups and downs of treating people who may (or may not) be destined to fight and lose the battle against this strong nemesis? How will I answer the tough questions regarding medical approaches to cancer? How will I respond to patients who indicate a desire to commit suicide or request my help in doing so? What can I tell families whose loved one is choosing treatments that will not help and will deteriorate his quality of life? Basing his responses on the Oath of Hippocrates, the author illustrates how adaptable this oath actually is when considering the secular society in which we function. The Cancer Experience instructs doctors, medical students, and health care workers involved in cancer care on the proper role of medicine, the role of the doctor, and the opportunities for connecting with patients as they help them make decisions regarding treatment and end of life issues. It helps patients understand the issues facing doctors as they assist them, care for them, and try to maintain both close personal relationships but enough emotional and professional distance in order to protect themselves from the stress and strain when medicine fails and patients must face the hardest choices. Here the author promotes a return to traditional medical values that promote closer doctor-patient relationships in an effort to promote trust, civility, and partnership.
An unprecedented constellation of experts—leading cancer doctors, policymakers, cutting-edge researchers, national advocates, and more—explore the legacy and the shortcomings from the fifty-year war on cancer and look ahead to the future. The longest war in the modern era, longer than the Cold War, has been the war on cancer. Cancer is a complex, evasive enemy, and there was no quick victory in the fight against it. But the battle has been a monumental test of medical and scientific research and fundraising acumen, as well as a moral and ethical challenge to the entire system of medicine. In A New Deal for Cancer, some of today’s leading thinkers, activists, and medical visionaries describe the many successes in the long war and the ways in which our deeper failings as a society have held us back from a more complete success. Together they present an unrivaled and nearly complete map of the battlefield across dimensions of science, government, equity, business, the patient provider experience, and more, documenting our emerging understanding of cancer’s many unique dimensions and offering bold new plans to enable the American health care system to deliver progress and hope to all patients.
Covers the most common cancers and strategies for nursing care.
Ras proteins are key molecular switches in cell signaling pathways that, when activated, trigger cell growth and division. Mutations that produce abnormally active Ras proteins are common in human cancers, particularly those of the pancreas, lung, and colon. These cancers can be difficult to treat because Ras oncoproteins have long been considered 'undruggable.' Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine covers the recent progress that has been made in understanding Ras biology, how Ras activation leads to tumorigenesis, and ways in which oncogenic Ras signaling may be targeted therapeutically. The contributors review the biochemical characteristics of the different Ras isoforms (HRAS, KRAS, and NRAS), their main effectors and signaling pathways, and the mutations that lead to their constitutive activation. Recent work showing that some Ras oncoproteins may be effectively inhibited by small molecules is covered, as is work on alternative targets (e.g., enzymes that catalyze posttranslational modifications of Ras) and inhibitors (e.g., nucleic acids). The authors also discuss how organoids and mouse models are being used to study tumor progression and therapeutic efficacy. This volume is therefore essential reading for all cancer biologists, cell and molecular biologists, and pharmacologists concerned with understanding and treating Ras-driven cancers.
Kate Pickert worked as a health-care journalist and knew medical treatment well, but it all changed when she was diagnosed with an aggressive type of breast cancer at age 35. Pickert used her journalistic skills to identify the cultural, scientific, and historical forces shaping the lives of breast-cancer patients in the modern age.
Dr. Keith Block is at the global vanguard of innovative cancer care. As medical director of the Block Center for Integrative Cancer Treatment in Evanston, Illinois, he has treated thousands of patients who have lived long, full lives beyond their original prognoses. Now he has distilled almost thirty years of experience into the first book that gives patients a systematic, research-based plan for developing the physical and emotional vitality they need to meet the demands of treatment and recovery. Based on a profound understanding of how body and mind can work together to defeat disease, this groundbreaking book offers: • Innovative approaches to conventional treatments, such as “chronotherapy”–chemotherapy timed to patients’ unique circadian rhythms for enhanced effectiveness and reduced toxicity • Dietary choices that make the biochemical environment hostile to cancer growth and recurrence, and strengthen the immune system’s ability to attack remaining cancer cells • Precise supplement protocols to tame treatment side effects, relieve disease-related symptoms, and modify processes like inflammation and glycemia that can fuel cancer if left untreated • A new paradigm for exercise and stress reduction that restores your strength, reduces anxiety and depression, and supports the body’s own ability to heal • A complete program for remission maintenance–a proactive plan to make sure the cancer never returns Also included are “quick-start” maps to help you find the information you need right now and many case histories that will support and inspire you. Encouraging, compassionate, and authoritative, Life over Cancer is the guide patients everywhere have been waiting for.