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An invaluable resource to the rapidly emerging field of pharmacogenomics—complete with case studies, clinical pearls, and treatment recommendations The aim of pharmacogenomics is to improve personalized medicine by taking into account how genes affect an individual’s tolerability and response to drugs. Approaching pharmacogenomics from the current clinical, scientific, and implementation perspectives, this guide serves as an invaluable evidence-based resource to the subject. Reflecting the shift from genetics to genomics in the pharmaceutical sphere, the book covers pharmacogenomics fundamentals; genotyping tests and evidence; clinical implementation; ethical, legal, and social issues; and more. You’ll also find illuminating case scenarios, clinical pearls, and evidence-based recommendations for treatments and alternatives based on CPIC, PharmGKB, and FDA guidelines.
Dialectical Behavior Therapy (DBT) has quickly become a treatment of choice for individuals with borderline personality disorder and other complicated psychiatric conditions. Becoming proficient in standard DBT requires intensive training and extensive supervised experience. However, there are many DBT principles and procedures that can be readily adapted for therapists conducting supportive, psychodynamic, and even other forms of cognitive behavioral treatments.Despite this, there is a dearth of easily accessible reading material for the busy clinician or novice. This new book provides a clinically oriented, user-friendly guide to understanding and utilizing the principles and techniques of DBT for non-DBT-trained mental health practitioners and is an ideal guide to DBT for clinicians at all levels of experience. Written by internationally recognized experts in suicide, self injury and borderline personality disorder, it features clinical vignettes, following patients through a series of chapters, clearly illustrating both the therapeutic principles and interventions.
In a negative therapeutic reaction the progress of treatment triggers a particular destructive dynamic in the patient. Initially, therapists considered it to be a result of the patient's pathology, but contemporary clinicians recognize that the therapist may significantly contribute to this process. Object relations clinicians see the individual as a social being that develops in relation to others whom the individual internalizes as good and bad objects. Jeffrey Seinfeld explores how an internal sabotaging self is identified with a rejecting object. This self is a reservoir of memories of how original caregivers rejected the child's needs, and the patient now expects the world to reject and disappoint her. If patients experience the therapist as a kind or caring person, they may feel that they are being lured into dependency and subsequent disappointment. Paradoxically, if patients feel attached to the therapist, this same attachment is experienced as a threatening dependency that must be destroyed. A relationship that could eventually strengthen the personality is rejected, and instead a negative reaction to the therapist and the therapeutic process is established. Jeffrey Seinfeld shows that in order for patients to heal, they must separate from the internal bad objects.This is often done with aggression against the therapist, who must be able to withstand the intense hostility, rage, and abuse of the patient. Only by surviving this aggression in the negative therapeutic reaction can the therapist allow the patient to integrate good and bad part objects in the transference. The therapist can eventually serve as a bridge in the integration of the divided good and bad selves and objects. Through case histories Seinfeld illustrates his way of entering into the patient's internal world. By helping patients understand the transference of their internal objects, they begin to understand their own experience of self and others, which leads to character change.
Clinical Primer of Rheumatology is designed as a concise, essential reference to aid practitioners in diagnosing and treating rheumatoid diseases. More than 200 photographs and many tables and charts provide easy access to information necessary to identify the cause of a patient's complaint and plan a course of therapy. Recommendations on when to refer a patient to a specialist are clearly indicated in the text. Comprehensive coverage of specific rheumatoid diseases is included along with information on sports and occupational-related pain syndromes.
Doctor Ellen G. Horovitz shares over 40 years of experience as she transliterates evidence-based art therapy into medical terminology. This revised and updated Third Edition spells out the how-to's behind producing art therapy assessments, process notes, significant sessions, objectives and modalities, termination summaries and internet-based assessments into translatable documentation, designed to dovetail within an interdisciplinary medical model. In addition, this third edition emphasizes information on how to use psychological applications and art therapy based assessments to ensure best practices and efficacy of patient care. This step-by-step methodology fashions these reports, placing art therapy on equal footing with all mental health clinicians and generates records, which serve as points of departure for practitioners. This text is designed as a teaching tool that lays the foundation to enhance pertinent skills that are important to patient practice, including the armament to write up clinically-based reports that serve as a model for the field. Additionally, the practitioner is offered sample formats, legends and abbreviations of clinical and psychiatric terms, guidelines for recordable events, instructions of writing up objectives, modalities, and treatment goals as well as training on composing progress versus process notes. The Appendices provides a wealth of information and forms to use in one's clinical practice. This must-have reference manual amasses information that will serve as a companion guide for every art therapist to formulate clinical reports, and it will aid patients toward their trajectory of wellness, recovery and, above all, health.
This brief Primer, assembled by top recognized hypnosis authorities, briefly presents the basic concepts of modern medical hypnosis and encourages mental health care practitioners to learn how to use hypnosis as an adjunct to standard medical care. It also lays the groundwork for the teaching and practice of hypnosis as part of the required syllabus for every medical and nursing school as well as graduate programs in clinical and counseling psychology. Medical Hypnosis Primer goes far in advancing the medical and factual aspects of this still greatly misunderstood field, and is of great value to practitioners, teachers, and students.
A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research regarding the application of pharmacology to the process of drug discovery. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This updated edition has been thoroughly revised to include material on quantifying drug efficacy through bias and cluster analysis, the impact of molecular dynamics and protein structural analysis, the real time kinetic analysis of drug effect, virtual screening for new drug chemical scaffolds, and much more. With full color illustrations and new examples throughout, this book remains a top reference for all industry and academic scientists that is also ideal for students directly involved in drug discovery or pharmacologic research. Highlights changes surrounding strategies for drug discovery, providing a comprehensive reference and featuring advances in the methods involved Includes multiple new sections, such as development and utilization of models in pharmacology, de-orphanization of new drug targets, predicting impact of disease on drug pharmacokinetics, and the impact of enzyme kinetics on drug-drug interactions Illustrates the application of rapid inexpensive assays to predict activity in the therapeutic setting, showing data outcomes and the limitations inherent in interpreting this data
"With this Second Edition of An EMDR Therapy Primer, Dr. Hensley has created a very clear step-by-step guide to assist the newly trained EMDR clinician. Not only will it help transition training into practice but also help those trained earlier who are looking to update their skills. I highly recommend this book for any EMDR clinician wanting to assure fidelity to the model and methods." —Rosalie Thomas, RN, PhD "I believe that Dr. Hensley has written a book that is simple, basic, and can mentor therapists who are EMDR trained and yet intimidated.This book brings us back to the basics." - Jennifer Lendl, PhD This is a step-by-step overview of the foundations of EMDR Therapy presented in easily accessible, conversational language. It helps both new and experienced clinicians to maximize their preparation and skills in using EMDR safely, confidently, and effectively. The second edition is fully revised to reflect the evolution of EMDR to an integrative psychotherapeutic approach and is intended for use as a companion to Francine Shapiroís seminal EMDR texts. It has been enriched with several new case histories along with extensive examples of successful EMDR reprocessing sessions. An abundance of new information addresses EMD versus EMDR; research on the mechanism, model, and methodology of EMDR Therapy; bilateral stimulation; ancillary targets; the why and the how of many key EMDR Therapy components; protocol for single and recent traumatic events; updated information about the cognitive interweave, future templates; and much, much more. The book provides concise coverage of the AIP model and EMDR principles, protocols, and procedures and addresses the types of targets accessed during the EMDR process. The book summarizes the Eight Phases of EMDR Therapy and the Stepping Stones of Adaptive Resolution the components of the standard EMDR protocol. The building blocks of EMDR Therapy past, present, and future are assessed with regard to appropriate targeting and successful outcomes, as are abreactions, blocked processing, and cognitive interweaves. Detailed case studies demonstrate strategies to assist the client in reaching adaptive resolution of trauma. New to the Second Edition: Completely revised and updated Reflects the evolution of EMDR to an integrative therapeutic approach Expands specialized EMDR techniques Includes new strategies to overcome obstacles Presents new transcripts and case studies Provides "Derailment Possibilities" to alert clinicians of potential obstacles to therapeutic success Extensive appendices include definitions for EMDR Therapy, EMDR Therapy scripts, and additional resources
The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments. Over 30 new figures and tables More human interest information to provide readers with historical facts on pharmacology research New section on therapeutics to help identify diseaes and drug treatments New section on new biological concepts relevant to pharmacological research (i.e., systems biology) New study sections organized with ASPET and other international pharmacology organizations New coverage of pharmacokinetics and drug disposition