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The philosophy behind this research methods text is to provide practical, how-to guidance in an accessible format. The authors hope to reach clinical students and postdoctoral trainees at the early stages of training to muster excitement by showing that research need not be either dull or threatening. Their goal is to "demystify the research process," with a style that is informative yet easy-to-read, humorous, and user friendly. One of our reviewers puts it best when he describes the book as "a true 'paperback' research mentor." The authors hope to hook students on research early in their studies so that they see it as a natural extension of their work rather than as drudgery to be endured just to get a degree. The ultimate hope is that this will lead to more direct-care practitioners getting involved in research after they leave school. This book is also different from any other on the subject in being problem oriented. It will emphasize research methods that are appropriate to most clinical settings and will deal with many issues of clinical research that are often ignored by other research methods books.
An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and the clinical research that guides medical decisions in the United States falls far short of this vision. The process of generating medical evidence through clinical trials in the United States is expensive and lengthy, includes a number of regulatory hurdles, and is based on a limited infrastructure. The link between clinical research and medical progress is also frequently misunderstood or unsupported by both patients and providers. The focus of clinical research changes as diseases emerge and new treatments create cures for old conditions. As diseases evolve, the ultimate goal remains to speed new and improved medical treatments to patients throughout the world. To keep pace with rapidly changing health care demands, clinical research resources need to be organized and on hand to address the numerous health care questions that continually emerge. Improving the overall capacity of the clinical research enterprise will depend on ensuring that there is an adequate infrastructure in place to support the investigators who conduct research, the patients with real diseases who volunteer to participate in experimental research, and the institutions that organize and carry out the trials. To address these issues and better understand the current state of clinical research in the United States, the Institute of Medicine's (IOM) Forum on Drug Discovery, Development, and Translation held a 2-day workshop entitled Transforming Clinical Research in the United States. The workshop, summarized in this volume, laid the foundation for a broader initiative of the Forum addressing different aspects of clinical research. Future Forum plans include further examining regulatory, administrative, and structural barriers to the effective conduct of clinical research; developing a vision for a stable, continuously funded clinical research infrastructure in the United States; and considering strategies and collaborative activities to facilitate more robust public engagement in the clinical research enterprise.
The number of psychiatric researchers does not seem to be keeping pace with the needs and opportunities that exist in brain and behavioral medicine. An Institute of Medicine committee conducted a broad review of the state of patient-oriented research training in the context of the psychiatry residency and considered the obstacles to such training and strategies for overcoming those obstacles. Careful consideration was given to the demands of clinical training. The committee concluded that barriers to research training span three categories: regulatory, institutional, and personal factors. Recommendations to address these issues are presented in the committee’s report, including calling for research literacy requirements and research training curricula tailored to psychiatry residency programs of various sizes. The roles of senior investigators and departmental leadership are emphasized in the report, as is the importance of longitudinal training (e.g., from medical school through residency and fellowship). As there appears to be great interest among numerous stakeholders and a need for better tracking data, an overarching recommendation calls for the establishment of a national body to coordinate and evaluate the progress of research training in psychiatry.
On March 3-4, 2016, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop in Washington, DC, bringing together key stakeholders to discuss opportunities for improving the integrity, efficiency, and validity of clinical trials for nervous system disorders. Participants in the workshop represented a range of diverse perspectives, including individuals not normally associated with traditional clinical trials. The purpose of this workshop was to generate discussion about not only what is feasible now, but what may be possible with the implementation of cutting-edge technologies in the future.
In the realm of health care, privacy protections are needed to preserve patients' dignity and prevent possible harms. Ten years ago, to address these concerns as well as set guidelines for ethical health research, Congress called for a set of federal standards now known as the HIPAA Privacy Rule. In its 2009 report, Beyond the HIPAA Privacy Rule: Enhancing Privacy, Improving Health Through Research, the Institute of Medicine's Committee on Health Research and the Privacy of Health Information concludes that the HIPAA Privacy Rule does not protect privacy as well as it should, and that it impedes important health research.
The volume evaluates major developments in psychiatry in India from the 1950s, and highlights the areas where Indian psychiatry has contributed to the development of the subject worldwide. The chapters review international as well as Indian developments in psychiatry and its sub-specialities. A wide range of clinical, research and policy-related topics have been covered in the volume, which begins with an overview of the history of psychiatry in India, moving on to developments in various sub-specialities of psychiatry in the last 60 years or so. It then specifically discusses developments in psychology and psychodynamics, general adult and child psychiatry, substance use psychiatry, community psychiatry, liaison psychiatry, and other psychiatric sub-specialities. Developments in treatment, the status of training and service in psychiatry and legal issues related to the practice of psychiatry in India are also included. The contributors to this volume are nationally and internationally recognized experts in different areas of psychiatry. Most of them have had some association, or are currently associated, with the Department of Psychiatry at the Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Religion and Mental Health: Research and Clinical Applications summarizes research on how religion may help people better cope or exacerbate their stress, covering its relationship to depression, anxiety, suicide, substance abuse, well-being, happiness, life satisfaction, optimism, generosity, gratitude and meaning and purpose in life. The book looks across religions and specific faiths, as well as to spirituality for those who don't ascribe to a specific religion. It integrates research findings with best practices for treating mental health disorders for religious clients, also covering religious beliefs and practices as part of therapy to treat depression and posttraumatic stress disorder. - Summarizes research findings on the relationship of religion to mental health - Investigates religion's positive and negative influence on coping - Presents common findings across religions and specific faiths - Identifies how these findings inform clinical practice interventions - Describes how to use religious practices and beliefs as part of therapy
Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research-from funders, to researchers, to journals, to physicians, and ultimately, to patients.
According to David Satcher, M.D., Ph.D., the 16th U.S. Surgeon General, we know a great deal more about treating mental illnesses than about preventing them and promoting mental health. In his foreword to Clinical Manual of Prevention in Mental Health, Dr. Satcher applauds this guide as timely and vital, as it provides new and emerging research on the importance of prevention in mental health. Clinical Manual of Prevention in Mental Health was conceived through discussions within the Prevention Committee of the Group for the Advancement of Psychiatry (GAP), and features contributions from 30 highly regarded clinicians and researchers who are experienced in the treatment and prevention of specific types of mental illnesses. Clinical Manual of Prevention in Mental Health will help you move toward widespread adoption of mental illness prevention in your own practice setting. This important new reference provides practical suggestions to help you work toward preventing, or implementing preventive measures in the treatment of Mood disorders Anxiety disorders Schizophrenia Substance use disorders Suicidality Family violence Conduct disorder and other adolescent disorders Late-life depression, dementia, and mild cognitive impairment Physical illnesses in psychiatric settings Cigarette smoking Compared with other areas of medicine, such as the prevention of infectious disease, our understanding of the prevention of mental illnesses remains in a relatively nascent state, especially in terms of how prevention can be incorporated into routine clinical practice. The authors of the various chapters have endeavored to balance reviewing the available research knowledge with providing guidance for practicing clinicians on how such knowledge can be incorporated into everyday practice. Clinical Manual of Prevention in Mental Health urges clinicians everywhere to inquire about risk factors and protective factors in patients' lives in addition to focusing on the presenting problem. It is the authors' intent to provide mental health professionals with the knowledge and practical applications necessary to be prevention-minded in all of their interactions with patients, families, and the community.