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The management of patients with thyroid cancers is a constantly changing field due to numerous developments in diagnostics and therapy. This book provides clinicians with up-to-date information on the current management of patients through all stages of their thyroid disease: from diagnosis of thyroid nodules through staging, extent and technique of surgery to adjuvant therapies, and follow-up schemes.
Now in its second edition utilizing brand new clinical case material, this popular, user-friendly text presents the diagnosis and treatment of thyroid cancer and related clinical issues, providing clinicians in endocrinology and oncology with the best real-world strategies to properly manage the various manifestations of thyroid cancer that they may encounter. Each chapter is a case report that opens with a unique clinical presentation, followed by a description of the diagnosis, assessment and therapy, as well as the case outcome, literature review, clinical pearls and pitfalls, and bibliography. All recommendations are based on evidence-based clinical practice guidelines and recent literature. Written by experts in the field, these cases illustrate treatment for both low- and high-risk differentiated thyroid cancer, including surgical approaches, radioiodine therapy, and novel chemotherapies and targeted therapies, as well as postoperative follow-up and special issues. Additional cases demonstrate the management of medullary thyroid cancer and anaplastic thyroid cancer. Topics new to the second edition include information on management of small thyroid cancers with “active surveillance” (without surgery), new chemotherapeutic approaches to advanced thyroid cancer, and new information on a lesion that is no longer considered to be thyroid cancer (Neoplastic Follicular Thyroid Neoplasm with Papillary-Like Features [NIFTP]), as well as material on external beam radiotherapy and new approaches to the management of anaplastic thyroid cancer. Pragmatic and reader-friendly, this second edition of Thyroid Cancer: A Case-Based Approach will be an excellent resource for clinical endocrinologists and oncologists, endocrine fellows, residents and students alike.
are new to this edition. The authors provide not only the The second edition of Thyroid Cancer: A Comp- most current review of their respective areas, but also their hensive Guide to Clinical Management marks the pub- own recommendations and approach. The reader is fo- cation of a markedly updated and expanded volume that warned that in many cases these approaches, albeit rooted covers all aspects of the etiology, pathogenesis, diag- sis, initial treatment, and long-term management of all in available data, may be empiric rather than based varieties of thyroid cancer. Like the first edition, it will upon clear-cut results of well-controlled clinical t- als. Nevertheless, controversial issues are examined serve as a valuable reference source for pathologists, and evidence-based recommendations are presented endocrine surgeons, endocrinologists, nuclear medicine when available. physicians, and oncologists. However, the biggest There are updated chapters on our current state change is that the second edition is significantly enlarged and expanded to encompass important and extensive of knowledge of the molecular changes in thyroid treatments of more topics related to nuclear medicine. cancer, molecular markers, and how targeted the- pies are being developed. New therapeutic trials of Nuclear medicine physicians and procedures play a key redifferentiation agents to restore the sodium iodide role in the management of thyroid cancer patients and in symporter when lacking and more traditional che- retrospect, a comprehensive discussion of topics related therapies are discussed, with referral sources listed for to that field was somewhat lacking in the first edition.
Written by a multidisciplinary team of experts involved in the development of standards and guidelines for its management in the USA, UK, Europe and Asia, the book contains succinct and knowledgeable summaries of the management of thyroid cancer. Every chapter describes a different aspect of care, and provides clear and detailed information about caring for patients with this group of tumors. This is an invaluable reference to health care professionals, from primary to tertiary care, involved in the management of thyroid cancer such as clinical nurse specialists, clinical psychologists, family medicine practitioners, specialists in palliative care (especially for anaplastic thyroid cancers), geneticists and surgeons, endocrinologists, oncologists, pathologists, and radiologists.
Thyroid cancer is the most common malignant endocrine tumor and is the seventh most common cancer seen in throughout out the world. The incidence of thyroid cancer has been increasing more rapidly than any other cancer in many of the cancer registries from different parts of the world. Although the majority of thyroid cancers have an indolent biological behaviour, different histological types have a diverse clinical behaviour. Well-differentiated thyroid cancers have an excellent survival, whereas poorly differentiated and anaplastic thyroid cancers have a very poor outcome. This volume of Head and Neck Cancer Clinics addresses advances, controversies and state-of-the-art treatment recommendations of various types of thyroid cancers.
The American Cancer Society recently estimated that about 45,000 new cases of thyroid cancer will be diagnosed in the United States, with three-quarters occurring in women. The overall 5-year survival rate is about 97%, making it one of the least lethal cancers. We are experiencing an epidemic of well-differentiated thyroid cancer, in part due to the widespread use of imaging modalities that detect thyroid nodules and microcarcinomas. Concurrently, there have been a number of recent advances in surgical treatment, as well as diagnostic modalities that allow us to detect small amounts of residual local and metastatic disease. Additionally, a reexamination of past treatment regimens has led to new recommendations regarding the use of radioactive iodine, and to new therapeutic options, such as targeted therapy which have supplanted the use of more toxic chemotherapy for metastatic cancer. Multiple academic organizations have developed consensus guidelines for the management of thyroid cancer, occasionally with conflicting recommendations. In Thyroid Cancer, a renowned group of authors presents a broad overview of the pathology, pathophysiology, diagnosis, and management of thyroid cancer, with an emphasis on recent evidence-based information. State-of-the-art and a significant contribution to the literature, Thyroid Cancer is an invaluable reference for endocrinologists, oncologists, nuclear medicine physicians, radiation oncologists, primary care physicians, and surgeons who deal with head and neck cancer.
This text provides a comprehensive, state-of-the art review of this field, and serves as a valuable resource for clinicians, surgeons and researchers with an interest in thyroid cancer. The book reviews new data about molecular genetics and molecular diagnostic approaches, covers diagnosis and treatment of localized disease, and conventional and newer therapies for dealing with recurrent and metastatic disease. Areas of controversy, with expert opinions from both outlooks, are also covered. Management of Differentiated Thyroid Cancer serves as a very useful resource for physicians and researchers dealing with, and interested in, this challenging malignancy. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up-to-date scientific and clinical information.
Now in its second edition utilizing brand new clinical case material, this popular, user-friendly text presents the diagnosis and treatment of thyroid cancer and related clinical issues, providing clinicians in endocrinology and oncology with the best real-world strategies to properly manage the various manifestations of thyroid cancer that they may encounter. Each chapter is a case report that opens with a unique clinical presentation, followed by a description of the diagnosis, assessment and therapy, as well as the case outcome, literature review, clinical pearls and pitfalls, and bibliography. All recommendations are based on evidence-based clinical practice guidelines and recent literature. Written by experts in the field, these cases illustrate treatment for both low- and high-risk differentiated thyroid cancer, including surgical approaches, radioiodine therapy, and novel chemotherapies and targeted therapies, as well as postoperative follow-up and special issues. Additional cases demonstrate the management of medullary thyroid cancer and anaplastic thyroid cancer. Topics new to the second edition include information on management of small thyroid cancers with "active surveillance" (without surgery), new chemotherapeutic approaches to advanced thyroid cancer, and new information on a lesion that is no longer considered to be thyroid cancer (Neoplastic Follicular Thyroid Neoplasm with Papillary-Like Features [NIFTP]), as well as material on external beam radiotherapy and new approaches to the management of anaplastic thyroid cancer. Pragmatic and reader-friendly, this second edition of Thyroid Cancer: A Case-Based Approach will be an excellent resource for clinical endocrinologists and oncologists, endocrine fellows, residents and students alike.
This issue of Endocrinology and Metabolism Clinics, guest edited by Dr. Michael Mingzhao Xing, is dedicated to Thyroid Cancer. Topics include, but are not limited to, Current Histological Classification of Thyroid Cancer, Molecular Pathogenesis and Mechanisms of Thyroid Cancer, Clinical Diagnostic Evaluation of Thyroid Nodules, Molecular Diagnostic Evaluation of Thyroid Nodules, Clinical Risk Stratification of Differentiated Thyroid Cancer, Molecular Risk Stratification of Differentiated Thyroid Cancer, Conventional Thyroidectomy in the Treatment of Primary Thyroid Cancer, Neck Dissection in the Surgical Treatment of Thyroid Cancer, Conventional Robotic Endoscopic Thyroidectomy for Thyroid Cancer, Transoral Endoscopic Thyroidectomy for Thyroid Cancer, Conventional Radioiodine Therapy for Differentiated Thyroid Cancer, Re-differentiation of Radioiodine-refractory Thyroid Cancer for Radioiodine Treatment, Management of Papillary Thyroid Microcarcinoma, Conservative Surveillance Management of Low-risk Papillary Thyroid Microcarcinoma, Thyroid-stimulating Hormone Suppression Therapy in Differentiated Thyroid Cancer, Diagnostic Imaging Testing in the Surveillance of Thyroid Cancer Recurrence, Novel Drug Treatments of Progressive Radioiodine-refractory Differentiated Thyroid Cancer, Management of Anaplastic Thyroid Cancer, and Management of Medullary Thyroid cancer.