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10 articles focus on worked hard materials of animal origin (shell, tusk, bone, antler) ranging chronologically from the Upper Palaeolithic to the Middle Ages. The authors have varied academic backgrounds that enhance the archaeological analyses carried out, often at first hand, on numerous collections from the Old and New Worlds.
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.
Exchanges between different cultures and institutions of learning have taken place for centuries, but it was only in the twentieth century that such efforts evolved into formal programs that received focused attention from nation-states, empires and international organizations. Global Exchanges provides a wide-ranging overview of this underresearched topic, examining the scope, scale and evolution of organized exchanges around the globe through the twentieth century. In doing so it dramatically reveals the true extent of organized exchange and its essential contribution for knowledge transfer, cultural interchange, and the formation of global networks so often taken for granted today.
The partition of fluid between the vascular and interstitial compartments is regulated by forces (hydrostatic and oncotic) operating across the microvascular walls and the surface areas of permeable structures comprising the endothelial barrier to fluid and solute exchange, as well as within the extracellular matrix and lymphatics. In addition to its role in the regulation of vascular volume, transcapillary fluid filtration also allows for continuous turnover of water bathing tissue cells, providing the medium for diffusional flux of oxygen and nutrients required for cellular metabolism and removal of metabolic byproducts. Transendothelial volume flow has also been shown to influence vascular smooth muscle tone in arterioles, hydraulic conductivity in capillaries, and neutrophil transmigration across postcapillary venules, while the flow of this filtrate through the interstitial spaces functions to modify the activities of parenchymal, resident tissue, and metastasizing tumor cells. Likewise, the flow of lymph, which is driven by capillary filtration, is important for the transport of immune and tumor cells, antigen delivery to lymph nodes, and for return of filtered fluid and extravasated proteins to the blood. Given this background, the aims of this treatise are to summarize our current understanding of the factors involved in the regulation of transcapillary fluid movement, how fluid movements across the endothelial barrier and through the interstitium and lymphatic vessels influence cell function and behavior, and the pathophysiology of edema formation. Table of Contents: Fluid Movement Across the Endothelial Barrier / The Interstitium / The Lymphatic Vasculature / Pathophysiology of Edema Formation
Keep up-to-date with the latest in innovative electronic information services! The Changing Landscape for Electronic Resources: Content, Access, Delivery, and Legal Issues focuses on the effects and challenges of providing electronic resources for libraries. The authors are librarians and other professionals with practical experience in current issues and developing trends. With this book, you will learn about technical, legal, and resource sharing developments that will contribute to the future distribution of global information in libraries. This book shows how libraries using electronic resources can reduce costs and save transaction time for large and small public libraries as well as academic libraries. It also reveals recent initiatives related to open source software and core standards for resource sharing and interlibrary loal, such as the Bath profile and the NISO Circulation Interchange Protocol (NCIP). Special features of this timely book include figures, diagrams, references, and Web sites. This book contains the wisdom and experience of professionals applying electronic resources to: interlibrary loan systems copyright and licensing open source software international data standards scholarly publishing The Changing Landscape for Electronic Resources will help you avoid many of the potential pitfalls of managing electronic content in the evolving modern library. This book will help you prepare for a future in which electronic access improves the range, speed, and quantity of cost-effective information services for patrons and resource-sharing partners.
Librarians work in an environment of constant change created by new technology, budget restraints, inflationary costs, and rising user expectations. New Directions in Reference examines how they can use new and innovative methods to design and deliver traditional reference services in a wide range of settings. The book's contributors relate first-hand experiences in libraries large and small, public and academic, and urban and rural dealing with a variety of changes, including virtual reference, music reference, self-service interlibrary loan, e-mail reference, and copyright law.