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sharing what they already know and what they would like to know about electricity. They are given an opportunity to use batteries, wire, bulbs, and motors to explore the concept of a complete circuit. Each Teacher Guide includes: Specific teaching and management strategies Detailed teaching sequences for teaching the first three phases of the Learning Experience (Getting Started; Exploring and Discovering; and Processing For Meaning) Reproducible masters for Student Science Notebook pages, Group Recording Sheets, and Home-School Worksheets Extension activities in science, language arts and social studies Assessment materials (an introductory questionnaire, embedded assessments, and a final questionnaire consisting of performance and written components) Science Background (provides general science concepts as they are introduced and developed in the module) to help prepare teacher Teacher and Student Resources section (annotated lists of children's books, teacher reference books, and technological aids)
This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders. - Provides interdisciplinary appeal in psychiatry, neurology, neuroscience, and genetics - Identifies key concepts, methods, and findings - Includes coverage of multiple disorders from autism to schizophrenia - Reviews specific genes associated with disorders - Discusses the genetic architecture of these syndromes - Explains how recent findings are influencing the understanding of biology - Clarifies the promise of these findings for future treatment
The Centers for Disease Control and Prevention estimate that 1 in 68 children in the United states is afflicted with autism spectrum disorders (ASD), yet at this time, there is no cure for the disease. Autism is characterized by delays in the development of many basic skills, most notably the ability to socialize and adapt to novelty. The condition is typically identified in children around 3 years of age, however the high heritability of autism suggests that the disease process begins at conception. The identification of over 500 ASD risk genes, has enabled the molecular genetic dissection of the pathogenesis of the disease in model organisms such as mice. Despite the genetic heterogeneity of ASD etiology, converging evidence suggests that these disparate genetic lesions may result in the disruption of a limited number of key biochemical pathways or circuits. Classification of patients into groups by pathogenic rather than etiological categories, will likely aid future therapeutic development and clinical trials. In this set of papers, we explore the existing evidence supporting this view. Specifically, we focus on biochemical cascades such as mTOR and ERK signaling, the mRNA network bound by FMRP and UBE3A, dorsal and ventral striatal circuits, cerebellar circuits, hypothalamic projections, as well as prefrontal and anterior cingulate cortical circuits. Special attention will be given to studies that demonstrate the necessity and/or sufficiency of genetic disruptions (e.g. by molecular deletion and/or replacement) in these pathways and circuits for producing characteristic behavioral features of autism. Necessarily these papers will be heavily weighted towards basic mechanisms elucidated in animal models, but may also include investigations in patients.
This book discusses the emergence of diverse functional organizations in the visual pathway which could be spontaneously and solely initiated by the random feedforward wiring of neural circuits. It demonstrates that the structure of ON and OFF retinal ganglion cell (RGC) mosaics is projected onto V1 by retino-cortical feedforward mapping to induce higher cognitive functions. This book will be beneficial for both theoretical and experimental neuroscientists, as well as for researchers using brain-inspired neural network models.
Now in its Third Edition, this text provides the background knowledge primary teachers need to plan effective programmes of work and answer children′s questions with confidence. The new edition links explanations of scientific concepts with children′s everyday experiences to help teachers and trainees foresee how they will present the subject knowledge to their pupils. Shaped by the National Curriculum, this text explains key scientific theories and concepts which pupils at primary level, including very able children, need in order to understand the observations and investigations they undertake. A CD ROM of 200 science investigations for young students is included with the new edition, allowing teachers to explore the practical application of topics covered in the book. This is an essential book for teachers, student teachers and anyone interested in the roots and growth of science education.
A major theoretical work by Brazilian dance scholar Christine Greiner explores the political relevance of bodily arts in the age of neoliberal globalization
From an award-winning neuroscience researcher with twenty years of teaching experience, Multiple Pathways to the Student Brain uses educator-friendly language to explain how the brain learns. Steering clear of “neuro-myths,” Dr. Janet Zadina discusses multiple brain pathways for learning and provides practical advice for creating a brain-compatible classroom. While there are an abundance of books and workshops that aim to integrate education and brain science, educators are seldom given concrete, actionable advice that makes a difference in the classroom. Multiple Pathways to the Student Brain bridges that divide by providing examples of strategies for day-to-day instruction aligned with the latest brain science . The book explains not only the sensory/motor pathways that are familiar to most educators (visual, auditory, and kinesthetic), it also explores the lesser known pathways--reward/survival, language, social, emotional, frontal lobe, and memory/attention--and how they can be tapped to energize and enhance instruction. Educators are forever searching for new and improved ways to convey information and inspire curiosity, and research suggests that exploiting different pathways may have a major effect on learning. Multiple Pathways to the Student Brain allows readers to see brain science through the eyes of a teacher—and teaching through the eyes of a brain scientist.
Packed with precise, step-by-step checklists, detailed illustrations, and informative chapter explanations, the Electrical Inspection Manual, 2011 Edition identifies important Code rules and provides guidance on how-to organize checklists by occupancy type to increase thoroughness and decrease the likelihood of overlooking potential problems. Written by certified electrical inspectors, and endorsed by the National Fire Protection Association (NFPA) and the International Association of Electrical Inspectors (IAEI), this fully illustrated manual explains significant tasks, defines terms, outlines key questions, and provides a concise overview of the electrical inspection process.
Fully integrative approach to the socibiology of caviomorph rodents Brings together research on social systems with that on epigenetic, neurendocrine and developmental mechanisms of social behavior Describes the social systems of many previously understudied caviomorph species, identifying the fitness costs and benefits of social living in current day populations as well as quantified evolutionary patterns or trends Highlights potential parallels and differences with other animal models