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Introduction to Chemical Exposure and Risk Assessment focuses on the principles involved in assessing the risks from chemical exposure. These principles include the perception of risk, an understanding of how numbers are handled, and how chemicals affect health. The book briefly describes the major sinks, such as water and air, where chemicals are introduced. This is followed by a discussion on how concentrations are estimated and risk assessments are made. A discussion of risk benefit analysis and a presentation of several case studies using the principles for assessing risks are also included.
This book is an essential guide and support to understanding of the science and policy, procedure and practice that underpins the REACH risk assessments required for the use and placing on the market of chemicals in the European Union. A clear understanding of information provision and how this affects the assessment of chemical safety is fundamentally important to the success of policy on chemicals and ultimately to the sustainability of the chemicals industry. Within the book, the scientific processes that underpin the policy are explained in a practical way. Importantly, it includes coverage of techniques to help solve the problems of using potentially risky and hazardous chemicals through the use of less hazardous alternatives and ‘green chemistry’, and also the analysis of the risks of the use of the most hazardous substances against the social and economic benefits of use. Chemical Risk Assessment: A Manual for REACH covers the following main themes: i) Assessment of chemical risk; ii) Risk management; iii) Hazard reduction, substitution and green chemistry; iv) Risk versus benefit – socio-economic analysis. The book acts as a practical guide and overview to chemicals risk assessment and risk management (in the EU context), as well as a support text for planning for the challenges of the future, which will see ever-increasing pressure to withdraw hazardous substances from the EU (and global) market, balanced against opportunities for innovation in the development of less hazardous chemicals.
In fact, with the control and containment of most infectious conditions and diseases of the past millennium having been achieved in most developed countries, and with the resultant increase in life expectancies, much more attention seems to have shifted to degenerative health problems. Many of the degenerative health conditions have been linked to thousands of chemicals regularly encountered in human living and occupational/work environments. It is important, therefore, that human health risk assessments are undertaken on a consistent basis - in order to determine the potential impacts of the target chemicals on public health.
Written over a period of 17 years, the Handbook of Chemical Risk Assessment exhaustively examines and analyzes the world literature on chemicals entering the environment from human activities. The three volumes cover chemicals recommended by environmental specialists of the U.S. Fish and Wildlife Service and other resource managers. The choices were based on the real or potential impact of each contaminant and on the knowledge available about their mitigation. The information for each chemical includes source and use; physical, chemical, and metabolic properties; concentrations in field collections of abiotic materials and living organisms; deficiency effects; lethal and sublethal effects; and proposed regulatory criteria for the protection of human health and sensitive natural resources. Each chapter selectively reviews and synthesizes the technical literature on a specific priority contaminant and its effects on the environment. Successful risk assessment relies heavily on extensive and well-documented databases. They often include too much - or too little - information about too many chemicals. Of the hundreds of thousands of chemicals discharged into the environment, only a small number have sufficient information to attempt preliminary risk assessment. Sold only as a three volume set, the Handbook of Chemical Risk Assessment provides you with the exact amount of information you need in a single resource.
Concern for the environment has become one of the big issues in modern society, and one of the chief concerns is the environmental impact of modern industrial production. A particularly sensitive issue is the possibility of accidents in industries where there may be severe consequences for people, property and the environment. At one time the nuclear industry was seen as the most likely to be the cause of significant environmental damage, but after the occurrence of several major accidents such as Seveso, Flixborough and Bhopal, that concern extends to much of the chemicals industry. Pressure from society, reflected by strong legislation, coupled with a greater understanding of the impact that chemical processing operations can have, has led to the adoption of higher profile safety and environmental management programs within the chemical industry. Under these programmes existing and new processes are rigorously examined to determine the possible causes and consequences of failure, and the results used to improve the process to make failure less likely. Any process audit, aimed at improving safety or lessening the environmental impact, cannot be carried out using intuition or experience alone, so the discipline of risk analysis has grown as a collection of tools and methods which can be utilized to give a quantitative assessment of the risks involved in operating any given process. In this new book the authors present risk analysis and reduction in a clear and unified way, emphasizing the various different methods which can be used together in a global approach to risk analysis in the chemical process industries. Originally conceived as a text book for graduate level courses in chemical engineering, the clear presentation and thorough coverage will ensure that anyone involved in risk assessment, environmental impact assessment or safety planning will find this book an invaluable source of reference.
Chemical process quantitative risk analysis (CPQRA) as applied to the CPI was first fully described in the first edition of this CCPS Guidelines book. This second edition is packed with information reflecting advances in this evolving methodology, and includes worked examples on a CD-ROM. CPQRA is used to identify incident scenarios and evaluate their risk by defining the probability of failure, the various consequences and the potential impact of those consequences. It is an invaluable methodology to evaluate these when qualitative analysis cannot provide adequate understanding and when more information is needed for risk management. This technique provides a means to evaluate acute hazards and alternative risk reduction strategies, and identify areas for cost-effective risk reduction. There are no simple answers when complex issues are concerned, but CPQRA2 offers a cogent, well-illustrated guide to applying these risk-analysis techniques, particularly to risk control studies. Special Details: Includes CD-ROM with example problems worked using Excel and Quattro Pro. For use with Windows 95, 98, and NT.
Risk assessment has been extensively developed in several scientific fields, such as environmental science, economics, and civil engineering, among others. In the aftermath of the SPS and GATT agreements on the use of risk analysis framework in food trade, signed in the 1990s, international organisations and governments adopted risk assessment as a science-based process to ensure food safety along the food chain. The food industry can also benefit from the use of this approach for food process optimisation and quality assurance. Risk Assessment Methods for Biological and Chemical Hazards in Food introduces the reader to quantitative risk assessment methods encompassing general concepts to specific applications to biological and chemical hazards in foods. In the first section, the book presents food risk assessment as methodology and addresses, more specifically, new trends and approaches such as the development of risk rating methods, risk metrics, risk-benefit assessment studies and quality assessment methods. Section II is dedicated to biological hazards. This section identifies the most relevant biological hazards along the food chain and provides an overview on the types of predictive microbiology models used to describe the microbial response along the food chain. Chapter 12 specifically deals with cross contamination and the quantitative methods that can be applied to describe this relevant microbial process. The development and application of dose-response models (i.e. mathematical function describing the relationship between pathogen dose and health response) are also covered in this section. In Section III, the book translates risk assessment concepts into the area of chemical hazards, defining the process steps to determine chemical risk and describing the uncertainty and variability sources associated with chemicals. Key Features: Presents new trends and approaches in the field of risk assessment in foods Risk assessment concepts are illustrated by practical examples in the food sector Discusses how quantitative information and models are integrated in a quantitative risk asssment framework Provides examples of applications of quantitative chemical risk assessment in risk management The book, written by renowned experts in their field, is a comprehensive collection of quantitative methods and approaches applied to risk assessment in foods. It can be used as an extensive guide for food safety practitioners and researchers to perform quantitative risk assessment in foods
The U.S. Department of State charged the Academies with the task of producing a protocol for development of standard operating procedures (SOPs) that would serve as a complement to the Chemical Laboratory Safety and Security: A Guide to Prudent Chemical Management and be included with the other materials in the 2010 toolkit. To accomplish this task, a committee with experience and knowledge in good chemical safety and security practices in academic and industrial laboratories with awareness of international standards and regulations was formed. The hope is that this toolkit expansion product will enhance the use of the previous reference book and the accompanying toolkit, especially in developing countries where safety resources are scarce and experience of operators and end-users may be limited.
Dynamic Risk Analysis in the Chemical and Petroleum Industry focuses on bridging the gap between research and industry by responding to the following questions: - What are the most relevant developments of risk analysis? - How can these studies help industry in the prevention of major accidents? Paltrinieri and Khan provide support for professionals who plan to improve risk analysis by introducing innovative techniques and exploiting the potential of data share and process technologies. This concrete reference within an ever-growing variety of innovations will be most helpful to process safety managers, HSE managers, safety engineers and safety engineering students. This book is divided into four parts. The Introduction provides an overview of the state-of-the-art risk analysis methods and the most up-to-date popular definitions of accident scenarios. The second section on Dynamic Risk Analysis shows the dynamic evolution of risk analysis and covers Hazard Identification, Frequency Analysis, Consequence Analysis and Establishing the Risk Picture. The third section on Interaction with Parallel Disciplines illustrates the interaction between risk analysis and other disciplines from parallel fields, such as the nuclear, the economic and the financial sectors. The final section on Dynamic Risk Management addresses risk management, which may dynamically learn from itself and improve in a spiral process leading to a resilient system. - Helps dynamic analysis and management of risk in chemical and process industry - Provides industry examples and techniques to assist you with risk- based decision making - Addresses also the human, economic and reputational aspects composing the overall risk picture
Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.