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Based on the success of the first edition, this second edition continues to build upon fundamental principles of biosensor design and incorporates recent advances in intelligent materials and novel fabrication techniques for a broad range of real world applications. The book provides a multi-disciplinary focus to capture the ever-expanding field of biosensors. Smart Biosensor Technology, Second Edition includes contributions from leading specialists in a wide variety of fields with a common focus on smart biosensor design. With 21 chapters organized in five parts, this compendium covers the fundamentals of smart biosensor technology, important issues related to material design and selection, principles of biosensor design and fabrication, advances in bioelectronics, and a look at specific applications related to pathogen detection, toxicity monitoring, microfluidics and healthcare. Features Provides a solid background in the underlying principles of biosensor design and breakthrough technologies for creating more intelligent biosensors Focusses on material design and selection including cutting-edge developments in carbon nanotubes, polymer nanowires, and porous silicon Examines machine learning and introduces concepts such as DNA-based molecular computing for smart biosensor function Explores the principles of bioelectronics and nerve cell microelectrode arrays for creating novel transducers and physiological biosensors Devotes several chapters to biosensors developed to detect and monitor a variety of toxins and pathogens Offers expert opinions on the future directions, challenges and opportunities in the field
From MEMS to Bio-MEMS and Bio-NEMS: Manufacturing Techniques and Applications details manufacturing techniques applicable to bionanotechnology. After reviewing MEMS techniques, materials, and modeling, the author covers nanofabrication, genetically engineered proteins, artificial cells, nanochemistry, and self-assembly. He also discusses scaling laws in MEMS and NEMS, actuators, fluidics, and power and brains in miniature devices. He concludes with coverage of various MEMS and NEMS applications. Fully illustrated in color, the text contains end-of-chapter problems, worked examples, extensive references for further reading, and an extensive glossary of terms. Details the Nanotechnology, Biology, and Manufacturing Techniques Applicable to Bionanotechnology Topics include: Nonlithography manufacturing techniques with lithography-based methods Nature as an engineering guide and contrasts top-down and bottom-up approaches Packaging, assembly, and self-assembly from ICs to DNA and biological cells Selected new MEMS and NEMS processes and materials, metrology techniques, and modeling Scaling laws, actuators, power generation, and the implementation of brains in miniaturizes devices Different strategies for making micromachines smarter The transition out of the laboratory and into the marketplace The third volume in Fundamentals of Microfabrication and Nanotechnology, Third Edition, Three-Volume Set, the book discusses top-down and bottom-up manufacturing methods and explains how to use nature as a guide. It provides a better understanding of how to match different manufacturing options with a given application that students can use to identify additional killer MEMS and NEMS applications. Other volumes in the set include: Solid-State Physics, Fluidics, and Analytical Techniques in Micro- and Nanotechnology Manufacturing Techniques for Microfabrication and Nanotechnology
The fabrication of MEMS has been predominately achieved by etching the polysilicon material. However, new materials are in large demands that could overcome the hurdles in fabrication or manufacturing process. Although, an enormous amount of work being accomplished in the area, most of the information is treated as confidential or privileged. It is extremely hard to find the meaningful information for the new or related developments. This book is collection of chapters written by experts in MEMS and NEMS technology. Chapters are contributed on the development of new MEMS and NEMS materials as well as on the properties of these devices. Important properties such as residual stresses and buckling behavior in the devices are discussed as separate chapters. Various models have been included in the chapters that studies the mode and mechanism of failure of the MEMS and NEMS. This book is meant for the graduate students, research scholars and engineers who are involved in the research and developments of advanced MEMS and NEMS for a wide variety of applications. Critical information has been included for the readers that will help them in gaining precise control over dimensional stability, quality, reliability, productivity and maintenance in MEMS and NEMS. No such book is available in the market that addresses the developments and failures in these advanced devices.
The latest developments in chemical and biological sensor research and development. Topics include: 1. new selective species recognition surfaces and materials; 2. molecular recognition materials and approaches to minimize non-specific binding; 3. semi-selective species recognition materials; 4. novel methods for signal processing, signal amplification, and detection; 5. detection systems for multiple analytes in complex samples; 6. sensor arrays; and 7. analytical systems and approaches.
The 9/11 attack on US soil has inadvertently heightened the need for preparation for other potential means of terrorist attack. In particular, both biological and chemical warfare have been at the top of the priority list for most governmental agencies as these reagents can be covertly prepared and disseminated to result in both widespread fear and casualty. Among many others, one primary preventive step in preparing for the above attacks is to establish a network for efficient surveillance and rapid detection such that an appropriate response to such attacks can be timely and effective. Over the years, primarily due to technological advances, both chemical and biological agents that are able to inflict mass destructions are becoming more diverse and complex. Subsequently, improvement of sensing devices for rapid and sensitive detection should also be made to keep pace with these engineered or emerging threat agents. Of particular interest, the ability to encompass advances in micro and nanofabrication techniques to enable sensing devices are especially of interest as they have been shown to offer desired advantages such as improved and enhanced functionality, increased efficiency and speed in their readout, reduction in their fabrication cost, and also reduced reagent consumption. Numerous innovative and exciting reports which took advantage of these techniques for both chemical and biological sensing have appeared over the last decade. This unique book is the only current publication that provides readers with a brief, yet concise, collection of the latest advances in chemical and biological agent detection and/or their surveillance. It compiles and gives in-depth detail on several detection schemes so that the reader can be provided with a general sense of these micro and nanoscale sensing systems and platforms. The book covers both well established and "next-generation" micro- and nano-scale sensors and/or sensing platforms. Sensors or sensing platforms covered range from the novel utilization of nanotubes, cantilevers, nano and/or microsized pores, engineered whole cell, to polymeric transistors for sensing purposes. As a result of these advances there has been a synergistic marriage of a myriad of techniques, ranging from chemical, engineering and biological, for the development of sensors, which was once traditionally thought to be reserved for the immunologists. The enabling of these new technologies will result in a much improved sensing network for the detection and surveillance of both chemical and biological warfare agents.The book also contains chapters from leading experts in the field of chemical and biological sensing platforms and will be invaluable reading for anybody in this field.
This issue of ECS Transactions is a compilation of papers presented at the 218th Meeting of the Electrochemical Society, held in Las Vegas from October 10 - 15, 2010. The papers presented covered the research and development in the field of chemical (gas, ion, bio and other) sensors, including molecular recognition surface, transduction methods, and integrated and micro sensor systems, as well as all aspects of MEMS/NEMS technology, including micro/nanomachining, fabrication processes, packaging, and the application of these structures and processes to the miniaturization of chemical sensors, physical sensors, biosensors, miniature chemical analysis systems and other devices.
The Handbook of Silicon Based MEMS Materials and Technologies, Second Edition, is a comprehensive guide to MEMS materials, technologies, and manufacturing that examines the state-of-the-art with a particular emphasis on silicon as the most important starting material used in MEMS. The book explains the fundamentals, properties (mechanical, electrostatic, optical, etc.), materials selection, preparation, manufacturing, processing, system integration, measurement, and materials characterization techniques, sensors, and multi-scale modeling methods of MEMS structures, silicon crystals, and wafers, also covering micromachining technologies in MEMS and encapsulation of MEMS components. Furthermore, it provides vital packaging technologies and process knowledge for silicon direct bonding, anodic bonding, glass frit bonding, and related techniques, shows how to protect devices from the environment, and provides tactics to decrease package size for a dramatic reduction in costs. - Provides vital packaging technologies and process knowledge for silicon direct bonding, anodic bonding, glass frit bonding, and related techniques - Shows how to protect devices from the environment and decrease package size for a dramatic reduction in packaging costs - Discusses properties, preparation, and growth of silicon crystals and wafers - Explains the many properties (mechanical, electrostatic, optical, etc.), manufacturing, processing, measuring (including focused beam techniques), and multiscale modeling methods of MEMS structures - Geared towards practical applications rather than theory
The papers included in this issue of ECS Transactions were originally presented in the symposium ¿Microfabricated and Nanofabricated Systems for MEMS/NEMS 8¿, held during the PRiME 2008 meeting of The Electrochemical Society, in Honolulu, Hawaii, from October 12 to 17, 2008.