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Impressive progress has been made in the general field of immunology which has made possible new understanding and pragmatic approaches to the patient with allergic disease. Indeed, one working in the field of immunology senses a major revolution of immunobiologic thinking, much of which has relevance to the clinical practice of allergy. To the practicing allergist, pediatrician, or internist who must deal with allergic patients, the surging new information may seem confusing and bewildering. As part of our comprehensive series on modern immunobiology which aims to digest this progress, we believe it is appropriate to devote an entire volume to the fundamental principles, new knowledge, and clinical lore on which the modern practice of allergy must be based. In the present volume we strive to bring together relevant contributions from leaders in the field of immunobiology with those whose work stands at the forefront of clinical practice. The advancing understanding has in numerous instances reached the point of clinical application, and we have tried to encompass in this volume the entire scope of modern allergy.
For decades, health care practitioners have relied on Middleton’s Allergy as their go-to reference for comprehensive information on allergic disorders. Now Middleton’s Allergy Essentials, by Drs. Robyn E. O'Hehir, Stephen T. Holgate, and Aziz Sheikh, offers a concise resource that’s both easily accessible and highly authoritative. Perfect for clinicians in primary and secondary care settings, this practical volume covers what is most useful in your daily practice, with a strong emphasis on disease diagnosis and management. A practical approach to evaluation, differential diagnosis, and treatment of allergic disorders, focused specifically on what the non-specialist needs to know for everyday practice. Each chapter begins with a handy summary of key concepts to help you quickly identify important information. Coverage of today’s hot topics includes asthma, drug allergies, food allergies and gastrointestinal disorders, anaphylaxis, atopic dermatitis, and allergic contact dermatitis. Concise sections on mechanisms are included where relevant, keeping you up to date with this rapidly evolving field. Authored by the same internationally recognized experts that produce Middleton’s Allergy, the definitive text in the field. Ideal for physicians, residents, general and family practitioners, nurse practitioners, primary care doctors, hospitalists, general internists – anyone who is called upon to make effective diagnostic and treatment decisions regarding allergic disorders.
First published in 1991. Investigative Pathology of Odontogenic Cysts presents a unique and succinct review of the pathology of odontogenic cysts. The book emphasizes investigative pathology of odontogenic cysts and uses numerous illustrations and tables to reinforce and summarize discussions presented in the text. The book's most important aspect is its attempt to bring together new information regarding odontogenesis and the pathogenesis of odontogenic cysts. Oral biologists and pathologists working with dental tissues will find this book an important reference resource.
This valuable work explores the comprehensive topic of pollinosis in allergic diseases. The first part of this book deals with the botanical aspects of pollinosis: physiology of pollen, aerobiology in the different countries, morphological data, and pollen chemistry. The drawings and tables are a valuable key for identification of pollens and preparation of pollen calendars. The other sections deal with the medical aspects of pollinosis: immunological basis, genetics, clinical pictures, diagnostic procedures and laboratory techniques, pharmacologic therapy and immunotherapy. Both the theoretical bases and practical applications are provided regarding each topic. Of tremendous benefit is the fact that, despite the book's focus on pollinosis, most sections are useful in facing all kinds of allergological problems. This book provides a basic reference for physicians and biologists involved in the field of allergy, both at the practical and research level.
From the first to the third of August, 1980, an international sym posium entitled "New Trends in Allergy" was held in Munich, sponsored by the Ludwig-Maximilian University, Munich, in cooperation with the German Society for Allergy and Immunity Research and the European Society for Dermatological Research. The symposium pursued two main goals: to bring allergy oriented colleagues from various specialties such as dermatology, otorhinolaryngology, pediatrics, internal medicine, immunology, and pulmonology together for interdisciplinary contacts and dis cussions; and to attract internationally known experts in an effort to disseminate information on new and fundamental develop ments in allergology. The fact that English has become the lingua franca at congresses for the exchange of ideas in medical specialties led to the decision to hold the symposium in English. In spite of the mild handicap this posed for some participants, it was also a major factor in the symposium's success. This book contains the papers delivered by the invited speakers together with the poster presentations. They cover both basic ex perimental research as well as clinical problems in allergology.
Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today's advances in pathology and medicine. - Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine - Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology - Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology
The editors of Mast Cell Biology, Drs. Gilfillan and Metcalfe, have enlisted an outstanding group of investigators to discuss the emerging concepts in mast cell biology with respect to development of these cells, their homeostasis, their activation, as well as their roles in maintaining health on the one hand and on the other, their participation in disease.
This textbook of basic and clinical immunology has been written primarily for medical and biology students who are receiving their first introduction to this fascinating field. Although we have presumed some knowledge of basic biology (particularly physiology and biochemistry), our primary intent has not been to cover in depth the latest research findings. Rather, we have sought to lay a firm foundation for subsequent reading in the laboratory and clinical sciences: internal medicine, pediatrics, microbiology, serology, physiology, cell biology, and genetics. Hence the first part of the text presents the various components of basic immunology, while the second shows how these elements interact under both normal physiologic and pathologic condi tions. To facilitate comprehension of the relationship between basic and clinical immunology, we have introduced cross-references throughout the book. A glossary of important terms has also been included. Selected references are provided with each chapter to guide the student to additional information on topics of special interest. Throughout the book we have attempted to convey to new students of immunology some of the excitement which the subject has long held for us. If we have succeeded, the task of writing will have been worthwhile.
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.