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Encouraged by the medicinal success of quinine, early 19th century scientists hoped strychnine, another plant alkaloid with remarkable properties, might also become a new weapon against disease. Physicians tried for over a century, despite growing evidence to the contrary, to treat everything from paralysis to constipation with it. But strychnine p
Combining theory and application, A Practical Guide to Stage Lighting provides a comprehensive analysis of lighting systems along with examples and illustrations of the technical tools and methods used in the industry. An entertaining and educational read, author Steven Louis Shelley draws from his 35+ years of diverse experience to explain how to get the job done along with real-life examples of projects from start to finish. Learn why some techniques are successful while others fail with 'Shelley's Notes' and 'Shelley's Soapbox,' all with a humor that guides you through complex problems and concepts. Highlights include: -Over 100 new topics, including analysis and application of the three categories of collaboration; a detailed examination of production meetings and one-on-one meetings; and meeting checklists with management and the creative team. -Over 50 new illustrations, including Shelley's Periodic Table of Fundamental Lighting Systems; groundplans, sections, and front elevations that illustrate basic system wash configurations for each direction of light. -Analysis, calculation, and step-by-step technical construction of each lighting system in the Hokey light plot. -Explanation of a manufacturer's cut sheet, and how to apply basic formulas to determine the beam size, footcandles, and gel transmission for lighting instruments. -Updated process of pre-programming computer lighting consoles prior to the load-in. -Comprehensive overview of archiving paperwork and softcopy for a production. Students and professionals will benefit from experience-based tips and techniques to prepare and execute a lighting design, along with learning how to avoid common traps.
This book is a collection of studies on mental health services in Ireland from the beginning of the nineteenth century to the present day. Essays cover overall trends in patient numbers, an exploration of the development of mental health law in Ireland, and studies on individual hospitals – all of which provide incredible insight into times past and yet speak volumes about mental health in contemporary Irish society. Topics include the famous nursing strike at Monaghan Asylum in 1919, when a red flag was raised over the building; extracts from Speedwell, a hospital newsletter, showing the social and sporting life at Holywell Hospital during the 1960s; an exploration of diseases such as beriberi and tuberculosis at Dundrum and the Richmond in the 1890s; the problems encountered by doctors in Ballinasloe Asylum as they tried to exert their authority over the Governors; and the experiences of Irish emigrants who found themselves in asylums in Australia and New Zealand. The book also includes a discussion of mental health services in Ireland 1959–2010, the first time such a chronology has been published. The editor, Pauline Prior, and the contributors, including Brendan Kelly, Dermot Walsh, Elizabeth Malcolm and E.M. Crawford, are well-known scholars within the disciplines of medicine, sociology and history, coming together for the first time to present an essential book on the history of mental health services in Ireland.
Written by a seasoned teacher, speaker, and writer in the field of chemistry, this text serves to provide a guide to the chemicals that make life possible and enrich the senses, as well as those that endanger it. This text combines the science and history of certain molecules and deals with the chemistry of each substance in an interesting and easily understandable manner. Topics covered include substances found in air and water, food, hydrocarbons, acids and alkalis, natural killers, unnatural killers, destructive molecules, pleasure molecules, natural healers, man-made healers, giant molecules, and vitamins.
In this final volume in the epic adventures of the Blades of the Moonsea, Geran Hulmaster seeks revenge against the mage who hurt his family and his people Rhovann Disarnnyl was once an arrogant elf lord who exploited the life of luxury his ancestral home in Myth Drannor afforded him. But that was before the upstart human Geran Hulmaster maimed him in a duel—and before Rhovann was exiled from Myth Drannor for practicing shadow magic. In a cruel act of vengeance, Rhovann drives Geran’s family from their ancestral lands, fills Hulburg with nightmarish goelms to enforce his will, and crushes the natives with the aggressive enforcement of unfair laws. But Geran Hulmaster will not stand idly by as Rhovann continues his tyrannical rule. Intent on making Rhovann’s life miserable, he violates his exile to stalk the streets of his former home, hunting down the wretched moon elf mage and rallying the oppressed people of Hulburg. But Geran’s enemies are as numerous as the laws he breaks in the name of revenge—and each and every one of them is determined to see him dead.
This book is the perfect link for learning how to perform the experiments after only having studied theory. In eight chapters more than 50 essential NMR experiments are described in detail. Special focus is put on the organic set of NMR spectra (1H, 13C-APT, COSY, NOESY, HSQC and HMBC). Different chapters deal with advanced organic NMR, selective methods, heteronuclear NMR, relaxation and diffusion measurements, organic applications and maintenance. Every experiment has a section providing the reader with the purpose and scope of the specific experiment. Every experiment is concluded with the spectrum as it is obtained under the conditions described. Questions and comments enable the reader to check their understanding. The authors are very experienced and the whole book is in full color, which enhances the reading experience and makes the spectra and other figures easier to understand. This book is strongly recommended for all students and researchers who are involved in the structural elucidation of chemical compounds both in practical education and in pursuing research, in particular if they handle an NMR spectrometer.
How can a plant as beautiful as the foxglove be so deadly and yet for more than a century be used to treat heart disease? The same is true of other naturally occurring molecules as will be revealed in this current book by award-winning author and chemist, John Emsley. More Molecules of Murder follows on from his highly-acclaimed earlier book Molecules of Murder, and again it deals with 14 potential poisons; seven of which are man-made and seven of which are natural. It investigates the crimes committed with them, not from the point of view of the murderers, their victims, or the detectives, but from the poison used. In so doing it throws new light on how these crimes were carried out and ultimately how the perpetrators were uncovered and brought to justice. Each chapter starts by looking at the target molecule itself, its discovery, its chemistry, its often-surprising use in medicine, its effects on the human body, and its toxicology. The rest of the chapter is devoted to murders and attempted murders in which it has been used. But, be reassured that murder by poison is not the threat it once was, thanks to laws which restrict access to such materials and to the skills of analytical chemists in detecting their presence in incredibly tiny amounts.
Called the “Fighting Cock of the Sioux” by U.S. soldiers, Hunkpapa warrior Gall was a great Lakota chief who, along with Sitting Bull and Crazy Horse, resisted efforts by the U.S. government to annex the Black Hills. It was Gall, enraged by the slaughter of his family, who led the charge across Medicine Tail Ford to attack Custer’s main forces on the other side of the Little Bighorn. Robert W. Larson now sorts through contrasting views of Gall, to determine the real character of this legendary Sioux. This first-ever scholarly biography also focuses on the actions Gall took during his final years on the reservation, unraveling his last fourteen years to better understand his previous forty. Gall, Sitting Bull’s most able lieutenant, accompanied him into exile in Canada. Once back on the reservation, though, he broke with his chief over Ghost Dance traditionalism and instead supported Indian agent James McLaughlin’s more realistic agenda. Tracing Gall’s evolution from a fearless warrior to a representative of his people, Larson shows that Gall contended with shifting political and military conditions while remaining loyal to the interests of his tribe. Filling many gaps in our understanding of this warrior and his relationship with Sitting Bull, this engaging biography also offers new interpretations of the Little Bighorn that lay to rest the contention that Gall was “Custer’s Conqueror.” Gall: Lakota War Chief broadens our understanding of both the man and his people.