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This book is the second of two volumes that together offer a comprehensive account of cutting-edge advances in the development of biomaterials for use within tissue engineering and regenerative medicine. In this volume, which is devoted to biomimetic biomaterials, the opening section discusses bone regeneration by means of duck’s feet-derived collagen scaffold and the use of decellularized extracellular matrices. The role of various novel biomimetic hydrogels in regenerative medicine is then considered in detail. The third section focuses on the control of stem cell fate by biomimetic biomaterials, covering exosome-integrated biomaterials for bone regeneration, cellular responses to materials for biomedical engineering, and the regulation of stem cell functions by micropatterned structures. Finally, the use of nano-intelligent biocomposites in regenerative medicine is addressed, with discussion of, for example, recent advances in biphasic calcium phosphate bioceramics and blood-contacting polymeric biomaterials. The authors are recognized experts in the interdisciplinary field of regenerative medicine and the book will be of value for all with an interest in regenerative medicine based on biomaterials.
This journal's volume contains articles describing the latest research results on biomaterials' properties used in implantology, tissue regeneration, and bone reconstruction. The analysis of the biomimetic approach to the design and calculation of thin shells, biomechanical research of features of human gait, investigation of organic nanoparticles synthesis for use in biosensors and biomedical applications and development of an accelerated variant of the electrocardiogram processing are also presented in this edition.
Principles of Biomaterials Encapsulation: Volume Two provides an expansive and in-depth resource covering the key principles, biomaterials, techniques and applications of encapsulation in translational medicine. The book details the various biomaterials available for encapsulation, including polymers, natural and synthetic biomaterials, porous materials, and more. The advantages and disadvantages of conventional and contemporary biomaterials for encapsulations are reviewed, along with advice on the most effective materials for both shell and core. The final part of the book describes a broad range of applications in regenerative medicine, uniquely bringing encapsulation into the worlds of translational medicine and tissue engineering. This book enables readers to learn about the pros and cons of different biomaterials for encapsulation, as well as how they can be utilized in many bodily systems and tissues, such as the respiratory, digestive, endocrine and cardiovascular systems. Written and edited by well-versed materials scientists with extensive clinical, biomedical and regenerative medicine experience, this book offers a deeply interdisciplinary look at encapsulation in translational medicine. - Details the various biomaterials available for encapsulation, as well as the advantages and disadvantages of conventional and contemporary biomaterials for encapsulations - Describes a broad range of applications in regenerative medicine, uniquely bringing encapsulation into the worlds of translational medicine and tissue engineering - Written and edited by well-versed materials scientists with extensive clinical, biomedical and regenerative medicine experience, offering an interdisciplinary approach
Takes a materials science approach, correlating structure-property relationships with function across a broad range of biological materials.
The accessible introduction to biomaterials and their applications in tissue replacement, medical devices, and more Molecular and cell biology is being increasingly integrated into the search for high-performance biomaterials and biomedical devices, transforming a formerly engineering- and materials science–based field into a truly interdisciplinary area of investigation. Biomimetic, Bioresponsive, and Bioactive Materials presents a comprehensive introduction to biomaterials, discussing how they are selected, designed, and modified for integration with living tissue and how they can be utilized in the development of medical devices, orthopedics, and other related areas. Examining the physico chemical properties of widely used biomaterials and their uses in different clinical fields, the book explores applications including soft and hard tissue replacement; biointeractive metals, polymers, and ceramics; and in vitro, in vivo, and ex vivo biocompatibility tests and clinical trials. The book critically assesses the clinical level of research in the field, not only presenting proven research, but also positing new avenues of exploration. Biomimetic, Bioresponsive, and Bioactive Materials contains everything needed to get a firm grasp on materials science, fast. Written in an accessible style and including practice questions that test comprehension of the material covered in each chapter, the book is an invaluable tool for students as well as professionals new to the field.
Bioinspired systems, technologies and techniques known as “biomimetics” or the “mimicry of nature,” represent a ground-breaking method of scientific research based on innovation and a creative design approach of the ‘nature’ laboratory to be applied to any scientific discipline. This approach and the associated way of thinking facilitates the cross-fertilization of scientific fields, integrating biology and the interdisciplinary knowledge featuring the evolution of models that have refined in nature within any scientific discipline.
This book summarizes naturally occurring and designed bio-inspired molecular building blocks assembled into nanoscale structures. It covers a fascinating array of biomimetic and bioinspired materials, including inorganic nanozymes, structures formed by DNA origami, a wide range of peptide and protein-based nanomaterials, as well as their applications in diagnostics and therapeutics. The book elucidates the mechanism of assembly of these materials and characterisation of their mechanical and physico-chemical properties which inspires readers not only to exploit the potential applications of nanomaterials, but also to understand their potential risks and benefits. It will be of interest to a broad audience of students and researchers spanning the disciplines of biology, chemistry, engineering, materials science, and physics.
This book reports on advanced biomaterials such as bioceramics, hydrogels, biopolymers, nanomaterials, membranes, and other compatible materials for medical applications. It introduces materials as bioactive coatings that utilize or mimic natural mechanisms and structures important for tissue and organ healing and repair. One section of the book is devoted to bone substitutes and osteogenic biomaterials. It also describes biomaterial-cell-tissue interactions, which are of critical importance for various applications in regenerative medicine, orthopedics, and implant functions. The chapters present fabrication methods and testing of various materials for medical applications. Special emphasis is given to natural patterns, theoretical models, and new insights into material characterization, particularly on fractal natural boundaries and mimicry designs taken from nature and implemented in photonics science and engineering. This multidisciplinary book is written by leading researchers and experts in their fields, and serves researchers, students, physicians, and engineers.
Fundamental Biomaterials: Metals provides current information on the development of metals and their conversion from base materials to medical devices. Chapters analyze the properties of metals and discuss a range of biomedical applications, with a focus on orthopedics. While the book will be of great use to researchers and professionals in the development stages of design for more appropriate target materials, it will also help medical researchers understand, and more effectively communicate, the requirements for a specific application. With the recent introduction of a number of interdisciplinary bio-related undergraduate and graduate programs, this book will be an appropriate reference volume for students. It represents the second volume in a three volume set, each of which reviews the most important and commonly used classes of biomaterials, providing comprehensive information on materials properties, behavior, biocompatibility and applications. - Provides current information on metals and their conversion from base materials to medical devices - Includes analyses of types of metals, discussion of a range of biomedical applications, and essential information on corrosion, degradation and wear and lifetime prediction of metal biomaterials - Explores both theoretical and practical aspects of metals in biomaterials
Biofabrication for Orthopedics A comprehensive overview of biofabrication techniques for orthopedics and their novel applications With an ever-increasing global population and the rise in the occurrence of orthopedic diseases amongst an aging population, it is essential for technological advances to meet this growing medical need. Orthopedic biofabrication is a cutting-edge field that seeks to produce novel clinical solutions to this mounting problem, through the incorporation of revolutionary technologies that have the potential to not only transform healthcare, but also provide highly automated and personalized patient solutions. With the advances in the discipline, there is a significant growing interest in biofabrication for orthopedics in research activity geared towards routine clinical use. Ideal for a broad readership amongst medical practitioners and scientists, Biofabrication for Orthopedics summarizes all aspects of the topic: detailed information on the technology, along with advanced developments, research progress, and future perspectives on biofabrication for orthopaedics—particularly on the potential applications for tissue engineering technologies. In doing so, the book describes the various biomaterials—natural and synthetic—use for orthopedics and discusses the many ways in which these materials can be used in all parts of the body. As such, it offers detailed information on a wide range of applications in the fields of biology and clinical and industrial manufacturing. Biofabrication for Orthopedics readers will also find: Insights into the applications of biofabrication technologies in various bodily functions Thorough discussion of different biofabrication techniques used in creating orthopedic products, like stereolithography, cell sheet and organ bioprinting, electrospinning, and microfluidics Discussion of a wide range of diverse functions, such as bone implants, skin regeneration, vascularization, meniscus remodeling, and more Biofabrication for Orthopedics is a useful reference for those in a variety of research fields like medical-related practitioners and scientists, materials science, medicine, and manufacturing, as well as the libraries who support them.