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This handbook presents the most recent technological advances and applications in the areas of biomedical photonics. This second edition contains introductory material and covers the state-of-the-art methods and instrumentation for biomedical photonic technologies. It integrates interdisciplinary research and development critically needed for scientists, engineers, manufacturers, teachers, students, and clinical providers to learn about the most recent advances and predicted trends in instrumentation and methods as well as clinical applications in important areas of biomedical photonics. Extensive references are provided to enhance further study.
This text begins by describing the basic principles and diagnostic applications of optical techniques based on detecting and processing the scattering, fluorescence, FT IR, and Raman spectroscopic signals from various tissues, with an emphasis on blood, epithelial tissues, and human skin. The second half of the volume discusses specific imaging technologies, such as Doppler, laser speckle, optical coherence tomography (OCT), and fluorescence and photoacoustic imaging.
Biomedical optics holds tremendous promise to deliver effective, safe, non- or minimally invasive diagnostics and targeted, customizable therapeutics. Handbook of Biomedical Optics provides an in-depth treatment of the field, including coverage of applications for biomedical research, diagnosis, and therapy. It introduces the theory and fundamental
This third edition of the biomedical optics classic Tissue Optics covers the continued intensive growth in tissue optics—in particular, the field of tissue diagnostics and imaging—that has occurred since 2007. As in the first two editions, Part I describes fundamentals and basic research, and Part II presents instrumentation and medical applications. However, for the reader’s convenience, this third edition has been reorganized into 14 chapters instead of 9. The chapters covering optical coherence tomography, digital holography and interferometry, controlling optical properties of tissues, nonlinear spectroscopy, and imaging have all been substantially updated. The book is intended for researchers, teachers, and graduate and undergraduate students specializing in the physics of living systems, biomedical optics and biophotonics, laser biophysics, and applications of lasers in biomedicine. It can also be used as a textbook for courses in medical physics, medical engineering, and medical biology.
Fundamentals of Photonics A complete, thoroughly updated, full-color third edition Fundamentals of Photonics, Third Edition is a self-contained and up-to-date introductory-level textbook that thoroughly surveys this rapidly expanding area of engineering and applied physics. Featuring a blend of theory and applications, coverage includes detailed accounts of the primary theories of light, including ray optics, wave optics, electromagnetic optics, and photon optics, as well as the interaction of light and matter. Presented at increasing levels of complexity, preliminary sections build toward more advanced topics, such as Fourier optics and holography, photonic-crystal optics, guided-wave and fiber optics, LEDs and lasers, acousto-optic and electro-optic devices, nonlinear optical devices, ultrafast optics, optical interconnects and switches, and optical fiber communications. The third edition features an entirely new chapter on the optics of metals and plasmonic devices. Each chapter contains highlighted equations, exercises, problems, summaries, and selected reading lists. Examples of real systems are included to emphasize the concepts governing applications of current interest. Each of the twenty-four chapters of the second edition has been thoroughly updated.
This volume describes concurrent engineering developments that affect or are expected to influence future development of digital diagnostic imaging. It also covers current developments in Picture Archiving and Communications System (PACS) technology, with particular emphasis on integration of emerging imaging technologies into the hospital environment.
Handbook of Optoelectronics offers a self-contained reference from the basic science and light sources to devices and modern applications across the entire spectrum of disciplines utilizing optoelectronic technologies. This second edition gives a complete update of the original work with a focus on systems and applications. Volume I covers the details of optoelectronic devices and techniques including semiconductor lasers, optical detectors and receivers, optical fiber devices, modulators, amplifiers, integrated optics, LEDs, and engineered optical materials with brand new chapters on silicon photonics, nanophotonics, and graphene optoelectronics. Volume II addresses the underlying system technologies enabling state-of-the-art communications, imaging, displays, sensing, data processing, energy conversion, and actuation. Volume III is brand new to this edition, focusing on applications in infrastructure, transport, security, surveillance, environmental monitoring, military, industrial, oil and gas, energy generation and distribution, medicine, and free space. No other resource in the field comes close to its breadth and depth, with contributions from leading industrial and academic institutions around the world. Whether used as a reference, research tool, or broad-based introduction to the field, the Handbook offers everything you need to get started. John P. Dakin, PhD, is professor (emeritus) at the Optoelectronics Research Centre, University of Southampton, UK. Robert G. W. Brown, PhD, is chief executive officer of the American Institute of Physics and an adjunct full professor in the Beckman Laser Institute and Medical Clinic at the University of California, Irvine.
This book highlights the analysis of new azimuth-independent methods of Stokes polarimetry and Mueller-matrix reconstruction of distributions of optical anisotropy parameters using spatial-frequency filtering of manifestations of phase (linear and circular birefringence) and amplitude (linear and circular dichroism) anisotropy for diagnosing changes in the orientational-phase structure of fibrillar networks of histological sections of biological tissues and polycrystalline films of biological fluids.
This book presents numerical computer-aided smart-methods as part of a comprehensive statistical, correlation and fractal analysis of laser polarimetry data. It highlights relationships between polarization (azimuth distributions, polarization ellipticities, Stokes vector parameters, Mueller matrix elements) parameters of laser images of biological tissues of a human corpse in different spectral ranges and temporal dynamics of their postmortem morphological changes. The book discusses the effectiveness of correlation analysis of two-dimensional distributions of polarization inhomogeneous images of histological sections of the main types of biological tissues in determining the time of death. It also discusses the development of basic principles of phase measurements (phasometry) of microscopic images of biological tissues to determine the age of death and the time of hematoma formation. Also presented in the book are possibilities of complex laser spectral photopolarimetry images of histological sections of biological tissues of human corpse in different spectral regions, with the simultaneous development and substantiation of a set of statistical and correlational criteria for objective determination of the time of death.
This book provides an essential overview of the basic principles of imaging modalities, accompanied by examples of their applications in modern clinical and associated pre-clinical studies. The monograph is based on the original results of investigation of the efficiency use of laser light and Mueller-matrix polarimetry approach for assessment of myocardial tissues towards confirmation the cause of death. A morphological analysis of necrotic changes in the myocardial tissue of patients that died due to heart attack, coronary heart disease and acute coronary insufficiency was carried out and the data and histological sections of the myocardium inspected utilizing Mueller-matrix mapping of tissue samples with polarized light. A unified optical model of polycrystalline structure of the myocardium is proposed, and the principles and regulations of Mueller-matrix description of its polarization manifestations are explored and developed. The book also provides a statistical and scale-selective wavelet analysis of polarization and Mueller-matrix maps. Finally, the key forensic medical criteria for the differential diagnosis of the cause of death due to necrotic and pathological changes in the morphological structure of the myocardium have been established