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This book describes medical applications of photochemistry. In the first part, a general introduction to photochemistry and related phototechnologies is provided. In the second part, photochemistry-based medical applications for diagnostics (biochips and bioimaging) and therapeutics (biomaterials for artificial organs, medical adhesives, dental materials, drug-delivery systems, tissue engineering, and photodynamic therapy) are described, with examples of recent research. The year 2015 is the International Year of Light and Light-Based Technologies. Light plays a vital role in our daily lives and is important in many interdisciplinary scientific fields in the twenty-first century. Light-based concepts have revolutionized medicine, including areas such as oncology, molecular biology, and surgery. Although photochemistry has contributed significantly to medicine directly and through photochemical fabrication of biomaterials, a book giving a comprehensive overview of recent progress has not been published until now. The aim of this book is to highlight the contributions of photochemistry in interdisciplinary fields of chemistry and medical engineering. This book will be useful for chemists who are interested in medical applications of photochemistry and engineers who are eager to learn the principles of photochemistry to enable its use in practical applications.
Photoacoustic and Photothermal Spectroscopy: Principles and Applications introduces the basic principles, instrumentation and major developments in the many applications of Photoacoustic and Photothermal Spectroscopy over the last three decades. The book explains the processes of sound generation by periodic optical excitation and ultrasonic generation by pulsed laser excitation and describes the workings of photoacoustic cells equipped with microphones and piezoelectric transducers. Photoacoustic imaging (PAI) is one of the fastest-growing imaging modalities of recent times. It combines the advantages of ultrasound and optical imaging techniques. These non-invasive and non-destructive techniques offer many benefits to users by enabling spectroscopy of opaque and inhomogeneous materials, (solid, liquid, powder, gel, gases) without any sample preparation, and more. - Written in a non-mathematical, simple-to-read manner - Presents recent developments in the field, along with the scope of future progress, including up-to-date references - Includes detailed illustrations, such as equipment layout, spectra, experimental setups, tables, photographs, and more
Nanotechnology for Biomedical Imaging and Diagnostics: From Nanoparticle Design to Clinical Applications reflects upon the increasing role of nanomaterials in biological and medical imaging, presenting a thorough description of current research as well as future directions. With contributions from experts in nanotechnology and imaging from academia, industry, and healthcare, this book provides a comprehensive coverage of the field, ranging from the architectural design of nanomaterials to their broad imaging applications in medicine. Grouped into three sections, the book: Elucidates all major aspects of nanotechnology and bioimaging Provides comprehensive coverage of the field, ranging from the architectural design of nanomaterials to their broad imaging applications in medicine Written by well-recognized experts in academia, industry, and healthcare, will be an excellence source of reference With a multidisciplinary approach and a balance of research and diagnostic topics, this book will appeal to students, scientiests, and healthcare professionals alike
Advances in Molecular Nanotechnology Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Molecular Nanotechnology. The editors have built Advances in Molecular Nanotechnology Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Molecular Nanotechnology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Molecular Nanotechnology Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Updated release includes the latest information on the Photoacoustic Probes for In Vivo Imaging
As a fast-growing imaging technology, photoacoustic (PA) imaging synergistically combines electromagnetic and ultrasonic waves providing higher contrast and resolution than conventional ultrasound imaging. This book presents the latest developments in this field, especially the advances in the detection of diseases using newly developed PA techniques.
This thesis covers a broad range of interdisciplinary topics concerning electromagnetic-acoustic (EM-Acoustic) sensing and imaging, mainly addressing three aspects: fundamental physics, critical biomedical applications, and sensing/imaging system design. From the fundamental physics perspective, it introduces several highly interesting EM-Acoustic sensing and imaging methods, which can potentially provide higher sensitivity, multi-contrast capability, and better imaging performance with less distortion. From the biomedical applications perspective, the thesis introduces useful techniques specifically designed to address selected challenging biomedical applications, delivering rich contrast, higher sensitivity and finer spatial resolution. Both phantom and ex vivo experiments are presented, and in vivo validations are progressing towards real clinical application scenarios. From the sensing and imaging system design perspective, the book proposes several promising sensing/imaging prototypes. Further, it offers concrete suggestions that could bring these systems closer to becoming “real” products and commercialization, such as replacing costly lasers with portable laser diodes, or integrating transmitting and data recording on a single board.
The detection and measurement of the dynamic regulation and interactions of cells and proteins within the living cell are critical to the understanding of cellular biology and pathophysiology. The multidisciplinary field of molecular imaging of living subjects continues to expand with dramatic advances in chemistry, molecular biology, therapeutics, engineering, medical physics and biomedical applications. Molecular Imaging: Principles and Practice, Volumes 1 and 2, Second Edition provides the first point of entry for physicians, scientists, and practitioners. This authoritative reference book provides a comprehensible overview along with in-depth presentation of molecular imaging concepts, technologies and applications making it the foremost source for both established and new investigators, collaborators, students and anyone interested in this exciting and important field. - The most authoritative and comprehensive resource available in the molecular-imaging field, written by over 170 of the leading scientists from around the world who have evaluated and summarized the most important methods, principles, technologies and data - Concepts illustrated with over 600 color figures and molecular-imaging examples - Chapters/topics include, artificial intelligence and machine learning, use of online social media, virtual and augmented reality, optogenetics, FDA regulatory process of imaging agents and devices, emerging instrumentation, MR elastography, MR fingerprinting, operational radiation safety, multiscale imaging and uses in drug development - This edition is packed with innovative science, including theranostics, light sheet fluorescence microscopy, (LSFM), mass spectrometry imaging, combining in vitro and in vivo diagnostics, Raman imaging, along with molecular and functional imaging applications - Valuable applications of molecular imaging in pediatrics, oncology, autoimmune, cardiovascular and CNS diseases are also presented - This resource helps integrate diverse multidisciplinary concepts associated with molecular imaging to provide readers with an improved understanding of current and future applications
This comprehensive book focuses on multimodality imaging technology, including overviews of the instruments and methods followed by practical case studies that highlight use in the detection and treatment of cardiovascular diseases. Chapters cover PET-CT, SPECT-CT, SPECT-MRI, PET-MRI, PET-optical imaging, SPECT-optical imaging, photoacoustic Imaging, and hybrid intravascular imaging. It also addresses the important issues of multimodality imaging probes and image quantification. Readers from radiology and cardiology as well as medical imaging and biomedical engineering will learn essentials of the field. They will be shown how the field has advanced quantitative analysis of molecularly targeted imaging through improvements in the reliability and reproducibility of imaging data. Moreover, they will be presented with quantification algorithms and case illustrations, including coverage of such topics such as multimodality image fusion and kinetic modeling. Yi-Hwa Liu, PhD is Senior Research Scientist in Cardiovascular Medicine at Yale University School of Medicine and Technical Director of Nuclear Cardiology at Yale New Haven Hospital. He is also an Associate Professor (Adjunct) of Biomedical Imaging and Radiological Sciences at National Yang-Ming University, Taipei, Taiwan, and Professor (Adjunct) of Biomedical Engineering at Chung Yuan Christian University, Taoyuan, Taiwan. He is an elected senior member of Institute of Electrical and Electronic Engineers (IEEE) and a full member of Sigma Xi of The Scientific Research Society of North America. Albert J. Sinusas, M.D., FACC, FAHA is Professor of Medicine (Section of Cardiovascular Medicine) and Radiology and Biomedical Imaging, at Yale University School of Medicine, and Director of the Yale Translational Research Imaging Center (Y-TRIC), and Director of Advanced Cardiovascular Imaging at Yale New Haven Hospital. He is a recipient of the Society of Nuclear Medicine’s Hermann Blumgart Award.