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Biological psychiatry has dominated psychiatric thinking for the past 40 years, but the knowledge base of the discipline has increased substantially more recently, particularly with advances in genetics and neuroimaging. The third edition of Biological Psychiatry has been thoroughly updated taking into account these developments. As in the earlier editions of the book, there are comprehensive reviews and explanations of the latest advances in neurochemistry, neuroanatomy, genetics and brain imaging— descriptions not only of methodologies but also of the application of these in clinical settings. It is within this context that there is a considerable emphasis in the book on brain–behaviour relationships both within and without the clinical setting. This edition has been enhanced by the inclusion of new chapters, one on anxiety and another on motivation and the addictions. The chapter that relates to treatments has been extended to include the latest information on brain stimulation techniques. The overall book is well illustrated in order to help with an understanding of the text. For the third edition, Professor Michael Trimble has been joined by Professor Mark George as co-author. These are two of the world's leading biological psychiatrists who both have considerable clinical as well as research experience which they have brought to the book. Unlike multiauthored texts, it has a continuity running through it which aids understanding and prevents repetition. This book is strongly recommended for all practising psychiatrists and trainees wishing for an up-to-date, authoritative, easy to digest and acessible review of the latest advances and conceptualizations in the field. It will also appeal to neurologists interested in neuropsychiatry and biological psychiatry or the psychiatric aspects of neurological disorders, as well as other practising clinicians (psychologists, social workers, nurses) in the mental health field.
Beginning with a tour of the brain, Dr. Hedaya explains how the brain works and how brain function relates to physical symptoms and cognitive and emotional well-being. He explains how biological psychiatrists consider the biology of the individual as an integral part of the whole picture and demonstrates a new way of conceptualizing clinical problems. Understanding Biological Psychiatry provides information in three basic areas: Chapters 1 and 2 outline basic scientific foundations and core concepts in biological psychiatry; chapters 3 and 4 review biological theories and medical mimics of the major psychiatric disorders; chapters 5 and 6 discuss medication and practical issues, including the basics of psychotropic medications and their role in the biopsychosocial approach. At the heart of this book is the author's proposal for a working alliance between therapists and psychiatrists - an important goal in today's growing managed care environment. The book has a practical bent, discussing, for example, when and how to refer to a psychiatrist, even describing how to explain this new perspective to a patient. The author's conversational style, as well as many figures, tables, and case illustrations, makes Understanding Biological Psychiatry a guide that is sure to be well-read and often referred to by therapists and physicians, as well as psychiatrists wanting to brush up on the biology of the mind.
A Textbook of Biological Psychiatry integrates the basic science concerning brain mechanisms of psychiatric disorders alongside surveys of present standard clinical treatment. Organized in a coherent and easy to follow structure, chapters expand across different levels of analysis, from basic mechanisms to clinical practice. This comprehensive reference provides an integrative treatment of the biochemistry of neurotransmission, behavioral pharmacology, and clinical aspects of psychiatric problems including depression, manic-depression, and mood disorders. Other chapters address the biological mechanisms and treatment of depression, anxiety, panic, obsessive-compulsive disorder, and addictions. The editor concludes with a perspective on the future of the field and prospects for understanding and effectively treating mood and anxiety disorders.
Lately, it seems that not a day passes without the media proclaiming yet another sensational breakthrough in the search for the physical origins of mental illness. But beyond all the fanfare and media hype, is there a single shred of hard, empirical evidence to substantiate the existence of "a gene for alcoholism," or "the brain chemistry behind schizophrenia"? More to the point, in fact, is it scientifically sound to limit the search for the roots of mental illness to processes occurring within the body, while dismissing socioeconomic, familial, and experiential influences as, at best, mere "triggering mechanisms"? And, if not, what harm is being done by psychiatry's current obsession with these somatic chimeras? This groundbreaking book offers answers to those questions and more. While Dr. Ross and Professor Pam clearly assert from the outset that biological psychiatry "is dominated by a reductionist ideology which distorts and misrepresents much of its research," this is by no means a raw polemic voiced by an overzealous opposition. Instead, it is a reasoned discourse based on a clear-sighted and methodical examination of the professional literature. Contributors to this volume include distinguished researchers and clinicians from the fields of psychiatry, psychology, sociology, and psychopharmacology. Their common purpose in coming together was to alert the mental health community to the ideological blind spots and conceptual errors in the basic logic and methodology of biological psychiatry, to demonstrate the need for a more scientifically based psychiatric practice, and to suggest alternative approaches to understanding and treating mental illness. Readers will find their arguments stimulating, provocative, and highly persuasive. Among the cutting-edge issues they explore are: the historical origins of biological psychiatry; genetics and mental illness; the current state of psychiatric training; psychopharmacology and drug therapy; the public health, legal, and ethical implications of biological psychiatry; and the funding, power, and politics of research. This book is essential reading for all mental health professionals. It also has many important things to say to health care administrators, political analysts, and public policy-makers. Of related interest . . . INSANITY The Idea and Its Consequences Thomas Szasz In this provocative book, Dr. Thomas Szasz, one of the most celebrated and controversial psychiatric thinkers of our time, presents a carefully crafted, systematic analysis of the precise character and practical consequences of the idea of mental illness. His findings and opinions have captured the attention of organized psychiatry and given everyone concerned with the human condition a better understanding of this almost universally misunderstood "disease." 1990 (0-471-52534-0) 432 pp. CRUEL COMPASSION Psychiatric Control of Society's Unwanted Thomas Szasz Cruel Compassion is the capstone of Thomas Szasz's critique of psychiatric practices. Reexamining psychiatric interventions from a cultural-historical and political-economic perspective, Szasz demonstrates that the main problem that faces mental health policymakers today is adult dependency. He gives us a sobering look at some of our most cherished notions about our humane treatment of society's unwanted and about ourselves as a compassionate and democratic people. 1994 (0-471-01012-X) 260 pp.
Biological psychiatry has dominated psychiatric thinking for the past 40 years, but the knowledge base of the discipline has increased substantially more recently, particularly with advances in genetics and neuroimaging. The third edition of Biological Psychiatry has been thoroughly updated taking into account these developments. As in the earlier editions of the book, there are comprehensive reviews and explanations of the latest advances in neurochemistry, neuroanatomy, genetics and brain imaging— descriptions not only of methodologies but also of the application of these in clinical settings. It is within this context that there is a considerable emphasis in the book on brain–behaviour relationships both within and without the clinical setting. This edition has been enhanced by the inclusion of new chapters, one on anxiety and another on motivation and the addictions. The chapter that relates to treatments has been extended to include the latest information on brain stimulation techniques. The overall book is well illustrated in order to help with an understanding of the text. For the third edition, Professor Michael Trimble has been joined by Professor Mark George as co-author. These are two of the world's leading biological psychiatrists who both have considerable clinical as well as research experience which they have brought to the book. Unlike multiauthored texts, it has a continuity running through it which aids understanding and prevents repetition. This book is strongly recommended for all practising psychiatrists and trainees wishing for an up-to-date, authoritative, easy to digest and acessible review of the latest advances and conceptualizations in the field. It will also appeal to neurologists interested in neuropsychiatry and biological psychiatry or the psychiatric aspects of neurological disorders, as well as other practising clinicians (psychologists, social workers, nurses) in the mental health field.
Biological Psychiatry: A Review of Recent Advances describes the developments in biological psychiatry. This book discusses the theories in the complex field of human disease, particularly psychiatric disease. Organized into six chapters, this book begins with an overview of the etiology and genetic basis of schizophrenia. This text then examines the various physiological and biochemical variables in schizophrenics. Other chapters consider the two types of depression, namely, reactive and endogenous. This book discusses as well the criteria of what symptom complexes constitute a particular psychiatric disease. The role of the brain in the control of learning, memory, behavior, and emotion is also reviewed. The final chapter deals with the psychoanalytic theory, which consists of a complex of theories of three various types. This book is a valuable resource for psychiatrists and physicians. Research workers in the various disciplines of neurobiology that encroach upon psychiatry will also find this book useful.
Due to their prevalence, pervasiveness and burden inflicted on men and women of today, psychiatric disorders are considered as one of the most important, sever and painful illnesses. This impairment of cognitive, emotional, or behavioural functioning is in some cases tragic. Aside from knowing the physical organic factors, such as infections, endocrinal illnesses or head injuries, the aetiology of psychiatric disorders has remained a mystery. However, recent advances in psychiatry and neuroscience have been successful in discovering subsequent pathophysiology and reaching associated bio-psycho-social factors. This book consists of recent trends and developments in psychiatry from all over the world, presented in the form of multifarious and comprehensive articles. The first two sections of the book are reserved for articles on schizophrenia and depression, two major illnesses present in this field. The third section of the book is reserved for addiction psychiatry, related not only to socio-cultural but also biological alterations. The last section of the book, titled Biological Neuropsychiatry, consists of three topics - updated molecular biology, fundamental neuroscience and clinical neuropsychiatric conditions. Doubtlessly, this book will be fruitful for future developments and collaboration in world psychiatry.
It is now widely recognised that biological psychiatry is rapidly coming into its own. For over the last three decades dramatic advances in this young discipline have been made, all of which attest to the staying power of the experimental method. Those who made this revolution in knowledge happen are a breed of investigators availing themselves of the tools of molecular biology, pharmacology, genetics, and perhaps, above all, the technology of neuroimaging. The introduction of the interdisciplinary method of approach to the study of psychopathology had made it very clear that neuroimaging, as a set of techniques, is unique in that it is gradually providing us with evidence supporting Kraepelin's original view that mental illness is closely associated with abnormal changes in the brain.Broadly speaking, there are presently two structural techniques in neuroimaging - computed tomography and magnetic resonance imaging (MRI) - and three functional techniques - single photon emission tomography (SPECT), positron emission tomography and magnetic resonance imaging (fMRI). Through PET technology, for example, we have learned that, in early brain development, the primitive areas, mostly the brain stem and thalamus, are the first to show high activity in an infant. This is followed by the development of cortical areas by year one. Between the ages of four to 10, the cortex is almost twice as active in the child as in the adult. This information alerts us to what might happen in the way of trauma in abused children, especially those under the age of three. Child abuse increases the risk of physical changes, not only in the stress systems, but also in brain development (Glaser and Weissman). In addition to the difficult problem of post-traumatic stress disorder (PTSD), we have to take into account the possibility of other types of mental illness as the consequences of child abuse. These include depression, eating disorders, and drug and alcohol problems.The combination of PET and fMRI represents a more remarkable example of the power of neuroimaging since the two have made it feasible to map accurately in vitro identifiable cortical fields, or networks. In a landmark NIH investigation of human cortical reorganization (plasticity), persuasive evidence was brought forward showing that the process of learning as a motor task involves a specific network of neurons. These neurons occur in the cortical field that is responsible for that particular task. Such findings are important partly because they provide evidence supporting the current notion that labor in the cortex is divided among ensembles of specialized neurons that cooperate in the performance of complex tasks. Cooperation, then, in this, sense implies crosstalk among ensembles and that signals are both processed and retransmitted to neighbouring ensembles. To understand the workings of these ensembles, much better spatial and temporal resolution in functional brain mapping is required. This can be achieved with an NMR instrument whose magnet is 4.1 Tesla or more.