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Biochemical Actions of Hormones, Volume V explores the nature of interaction of multiple hormones in regulating specific phenotypes. This volume is organized into 11 chapters that include discussions on the developments in the understanding of the biochemistry and molecular biology of hormones. The opening chapters deal with the modifications of chromatin structure by hormones, the regulation of exocytosis, ontogeny of estrogen receptors, and the hormonal regulation of cells of the seminiferous tubule. The discussions then shift to the advances on the progesterone receptor, the role of glucocorticoids in the integration of mammary tumor virus genes, and a model system for estrogen action. Other chapters examine the physiology, molecular action, and biological effects of somatomedins, epidermal growth factors and 1,25-dihydroxyvitamin. The remaining chapters focus on multihormone control of mRNA for a specific hepatic protein. This book is of great value to endocrinologists.
The Structure and Function of Nervous Tissue, Volume V: Structure III and Physiology III covers topics relating to nerve growth factor (NGF), neuroglia, central myelinated axon, adrenal medulla, and saccus vasculosus of the nervous system. The book begins with the physicochemical properties of the NGF molecule, followed by the neuroglial participation in the removal of debris from damaged central nervous system (CNS). It discusses the regional distribution and biochemical characteristics of two steroid-binding systems, one for estradiol and the other for corticosterone. It also presents studies on "split-brain, an expression coined by Sperry (1961) to characterize an organism whose brain has been partially divided into two by surgical transection of the commissural fibers crossing the midline, in lower vertebrates, mammals, and primates. The book ends with electrophysiological studies of learning in simplified nervous system preparations. This book serves as a reference work for graduate students in a variety of disciplines and for those specializing in particular aspects of nervous tissue study.
The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume V explores the contribution of molecular biology and gene cloning approaches to the advancement of plasma protein structure, function, and genomic organization studies. This volume is composed of five chapters and begins with a discussion on the DNA sequences and chromosomal location of plasma protein genes, specifically the cloning and sequencing of immunoglobulin genes. These topics are followed by a discussion on the advances in relation to discovered genetic variants present either as normal phenotypes or in dyslipoproteinemic states associated with cardiovascular disease. A chapter highlights the application of molecular biology techniques to the study of gene structure and the translational and maturation steps of every major plasma apolipoprotein. Another chapter emphasizes the unique features of protein structure and the conformational changes that characterize the assembly of macromolecular complexes in plasma and on cell surfaces. The concluding chapter provides a comprehensive review of the integration of molecular biology, physiology, and pathology of plasma proteins and their response in inflammation. This book will be of great value to molecular biologists, physiologists, pathologists, and clinicians.
The Hormones: Physiology, Chemistry and Applications, Volume V covers the advances in understanding the nature and function of hormones. This seven-chapter volume is a continuation of Volume IV on the endocrinology of plant and non-mammalian animal hormones. The introductory chapters examine the structure, metabolite actions, and some other chemical aspects of pituitary hormones. The following chapter explores the physiological, biochemical, and phylogenetic aspects of thyroid hormones, as well as brief description of thyroid cytology and process kinetics related to the thyroid. This chapter also presents mathematical models describing the processes of accumulation and binding of iodide in the thyroid, along with the release and metabolism of thyroid hormone. These topics are followed by discussions on the methods and concepts used for in vivo studies with labeled steroids in man. A chapter focuses on the role of hormones on tumorigenesis and tumor growth. Another chapter considers the concepts of mode of action of other hormones, such as insulin, epinephrine, and estradiol. The concluding chapter treats some examples of endocrine disease from the standpoint of the biological problems. Endocrinologists, physiologists, biochemists, phylogeneticists, and researchers who are interested in expanding knowledge on hormones will find this book invaluable.
Comparative Biochemistry: A Comprehensive Treatise, Volume V: Constituents of Life—Part C focuses on the structure and distribution of amino acids, distribution and metabolism of inorganic nitrogen compounds, acid metabolism, and comparative biochemistry of halides. The selection first offers information on the structure and distribution of amino acids and the distribution and metabolism of inorganic nitrogen compounds. Discussions focus on proteinogenous amino acids, nonproteinogenous amino acids, general aspects of inorganic nitrogen metabolism, and distribution and metabolism of nitrate, nitrite, and molecular nitrogen, ammonia, and hydrazine. The text then tackles citric acid cycle and other cycles and comparative biochemistry of collagen. The publication examines photosynthesis and halides. Topics include transfer of energy along the photosynthetic chain, carbon dioxide reduction, photosynthesis and phosphorylation, quantum yields and the efficiency of light energy conversion, chlorine, bromine, and iodine. The selection is a dependable source of data for readers interested in the constituents of life.
* Written by leading clinicians with greater emphasis on clinical practice, rather than basic science
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