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This timely book provides an overview of natural products/botanicals used for the management of insect-pest and diseases. It will help readers to update and widen their knowledge about natural products and their bio-activities against plant pathogens. The volume explores activity, chemistry, toxicity and geographic distribution of plants. Discussions concerning the methodology used for the detection of active principles, their mode of action and commercial prospects are of utmost importance and worthy of note. - Focuses on recent achievements in natural bio-actives - Global coverage of natural products / plants - Targets the most important issues of natural botanicals/ biocides - Includes innovative ideas with lucid explanations - Contains specialized chapters, such as, natural control of multi-drug resistant organisms, anti-salmonella agents, natural house-dust-mite control agents, and naturally occurring anti-insect proteins, etc. - Covers research on bioactives: From Lab to Field and Field to Market - Includes eco-friendly and economically viable herbal technology
Phytomedicine: A Treasure of Pharmacologically Active Products from Plants aims to present updated knowledge of plant-based medicines in terms of their research and development, production, and utilization, from the viewpoint of sustainability and by using the latest technologies. The book explores different phytometabolites on a mass scale, coupled with the efficacy, performance and applicability on target organisms to treat curable and fatal diseases. Readers will find a coherent package of phytotherapeutic information regarding inclusive assortment of research based, scientific amplitude of metabolites from the plant world encompassing various action plans. Information is presented sequentially regarding phytochemistry, biological activity and the serviceable aspects of bioactive compounds. The book also addresses various advancements and achievements of novel drugs from plants using molecular and enzymatic activities, and various technological tools in an ecofriendly fashion. Discusses phytotherapeutic properties for a wide range of medical conditions, including anti-pyretic, anti-infective, anti-malarial, Anti-AIDS, anti-diabetic, anti-cancerous, immune-modulatory applications Includes a discussion of synergistic effects of formulations and antagonistic drug interactions Addresses advancements and achievements of novel plant-based drugs using molecular, enzymatic activities and various technological tools in an eco-friendly fashion
This timely and original handbook paves the way to success in plant-based drug development, systematically addressing the issues facing a pharmaceutical scientist who wants to turn a plant compound into a safe and effective drug. Plant pharmacologists from around the world demonstrate the potentials and pitfalls involved, with many of the studies and experiments reported here published for the first time. The result is a valuable source of information unavailable elsewhere.
Herbal Biomolecules in Healthcare Applications presents extensive detailed information on all the vital principles, basics and fundamental aspects of multiple herbal biomolecules in the healthcare industry. This book examines important herbal biomolecules including alkaloids, glycosides, flavonoids, anthraquinones, steroids, polysaccharides, tannins and polyphenolic compounds, terpenes, fats and waxes, proteins and peptides, and vitamins. These herbal biomacromolecules are responsible for different bioactivities as well as pharmacological potentials. A systematic understanding of the extraction, purification, characterization, applications of these herbal biomolecules and their derivatives in healthcare fields is developed in this comprehensive book. Chapters explore the key topics along with an emphasis on recent research and developments in healthcare fields by leading experts. They include updated literature review of the relevant key topics, good quality illustrations, chemical structures, flow charts, well-organized tables and case studies. Herbal Biomolecules in Healthcare Applications will be useful for researchers working on natural products and biomolecules with bioactivity and nutraceutical properties. Professionals specializing in scientific areas such as biochemistry, pharmacology, analytical chemistry, organic chemistry, clinics, or engineering focused on bioactive natural products will find this book useful. - Provides a study of different type of biomolecules from herbal extracts and their bioactivities as well as their application in the healthcare industry - Contributions by global leaders and experts from academia, industry and regulatory agencies, who have been considered as pioneers in the application of herbal biomolecules in the diverse healthcare fields - Includes updated literature review along with practical examples and research case studies
The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef
Drug repurposing or drug repositioning is a new approach to presenting new indications for common commercial and clinically approved existing drugs. For example, chloroquine, an old antimalarial drug, showed promising results for treating COVID-19, interfering with MDR in several types of cancer, and chemosensitizing human leukemic cells.This book focuses on the hypothesis, risk/benefits, and economic impacts of drug repurposing on drug discovery in dermatology, infectious diseases, neurological disorders, cancer, and orphan diseases. It brings together up-to-date research to provide readers with an informative, illustrative, and easy-to-read book useful for students, clinicians, and the pharmaceutical industry.
Phytomedicine has become more important and gained constant improvement today for the betterment of health. Herbal medicine plays a significant role in the development of new drugs, contrary to the modern medicinal systems. For more than a decade, there has been a drastic improvement in phytomedicine across the world. This growth has reached a higher level in development by pharmaceutical industries everywhere. People have drifted toward herbal medication and practices for their food and health care. Therefore, in order to create abundant interest in the research of phytosciences, this book is one of the better reference tools. The bioactive compounds in plants need to be explored to know the scientific value and therapeutic properties of the medicinal plants against many diseases. This book contains chapters that are relevant to the advanced research in herbal medicines and will enlighten readers to the importance of medicinal plants as daily sources of nutrition and cures for diseases. This book highlights the unique features of the plants that have not been studied so far for their therapeutic potential. To prove the efficacy of medicinal plants, they have to be studied, examined, and scientifically verified. Hence, this book will better serve the researchers working under different aspects of phytomedicine. Features • The information provided through scientific validation is useful to study the pharmacological activity of herbals and their administration in the modern era. • The readers can find clear understanding in the research and development of phytopharmaceutical drugs. • The ideas incorporated in each chapter reveal the knowledge gained in studying the biological activities of the compounds present in the plant, which are indeed most worthy for the development of drugs. • The harvesting of new ideology toward modern scientific technologies that are employed in the field of pharmacological research.
There are significant concerns regarding the potential side effects from the chronic use of conventional drugs such as corticosteroids, especially in children. Herbal therapy is less expensive, more readily available, and increasingly becoming common practice all over the world. Such practices have both their benefits and risks. However, herbal self-therapy might have serious health consequences due to incorrect self-diagnosis, inappropriate choice of herbal remedy or adulterated herbal product. In addition, absence of clinical trials and other traditional safety mechanisms before medicines are introduced to the wider market results in questionable safe dosage ranges which may produce adverse and unexpected outcomes. Therefore, the use of herbal remedies requires sufficient knowledge about the efficacy, safety and proper use of such products. Hence, it is necessary to have baseline data regarding the use of herbal remedies and to educate future health professionals about various aspects of herbal remedies.
Phytochemicals are naturally occurring bioactive compounds found in edible fruits, plants, vegetables, and herbs. Unlike vitamins and minerals, phytochemicals are not needed for the maintenance of cell viability, but they play a vital role in protecting neural cells from inflammation and oxidative stress associated with normal aging and acute and chronic age-related brain diseases. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the advances in our understanding of the potential neuroprotective benefits that these naturally occurring chemicals contain. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the role that a number of plant-based chemical compounds play in a wide variety of neurological disorders. Chapters explore the impact of phytochemicals on neurotraumatic disorders, such as stroke and spinal cord injury, alongside neurodegenerative diseases such as Alzheimer's and Parkinson's Disease, as well as neuropsychiatric disorders such as depression and schizophrenia. The chapters and sections of this book provide the reader with a big picture view of this field of research. Neuroprotective Effects of Phytochemicals in Neurological Disorders aims to present readers with a comprehensive and cutting edge look at the effects of phytochemicals on the brain and neurological disorders in a manner useful to researchers, neuroscientists, clinical nutritionists, and physicians.
Water Extraction of Bioactive Compounds: From Plants to Drug Development draws together the expert knowledge of researchers from around the world to outline the essential knowledge and techniques required to successfully extract bioactive compounds for further study. The book is a practical tool for medicinal chemists, biochemists, pharmaceutical scientists and academics working in the discovery and development of drugs from natural sources. The discovery and extraction of bioactive plant compounds from natural sources is of growing interest to drug developers, adding greater fuel to a simultaneous search for efficient, green technologies to support this. Particularly promising are aqueous based methods, as water is a cheap, safe and abundant solvent. Water Extraction of Bioactive Compounds: From Plants to Drug Development is a detailed guide to the fundamental concepts and considerations needed to successfully undertake such processes, supported by application examples and highlighting the most influential variables. Beginning with an introduction to plants as sources of drugs, the book highlights the need for a move towards both more rational and greener techniques in the field, and presents multiple innovative water-based strategies for the discovery and extraction of bioactive constituents of botanicals. A broad range of available techniques are reviewed, including conventional and pressurized hot water extraction techniques, intensified processes such as microwave-assisted, ultrasound-assisted processes, and enzyme assisted extraction, and processes using combined techniques. - Covers the theoretical background and range of techniques available to researchers, helping them to select the most appropriate extraction method for their needs - Presents up-to-date and cutting edge applications by international experts - Highlights current use and future potential for industrial scale applications - Offers a thorough introduction to plants as sources of drugs, highlighting strategies for the discovery of novel bioactive constituents of botanicals