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Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow's clinician scientists and future leaders in discovery science. - Serves as a helpful guide for clinical researchers who lack a conventional science background - Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms - Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data - Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)
The Eye: Basic Sciences in Practice provides highly accessible, concise coverage of all the essential basic science required by today's ophthalmologists and optometrists in training. It is also essential reading for those embarking on a career in visual and ophthalmic science, as well as an invaluable, current refresher for the range of practitioners working in this area. This new fourth edition has now been fully revised and updated in line with current curricula, key research developments and clinical best practice. It succinctly incorporates the massive strides being made by genetics and functional genomics based on the Human Genome Project, the new understanding of how the microbiome affects all aspects of immunology, the remarkable progress in imaging technology now applied to anatomy and neurophysiology, as well as exciting new molecular and other diagnostic methodologies now being used in microbiology and pathology. All this and more collectively brings a wealth of new knowledge to students and practitioners in the fields of ophthalmology and visual science. For the first time, this (print) edition also now comes with bonus access to the complete, fully searchable electronic text - including carefully selected additional information and new video content to further explain and expand on key concepts - making The Eye a more flexible, comprehensive and engaging learning package than ever before. The only all-embracing textbook of basic science suitable for trainee ophthalmologists, optometrists and vision scientists - other books concentrate on the individual areas such as anatomy. Attractive page design with clear, colour diagrams and text boxes make this a much more accessible book to learn from than many postgraduate textbooks. Presents in a readable form an account of all the basic sciences necessary for an understanding of the eye - anatomy, embryology, genetics, biochemistry, physiology, pharmacology, immunology, microbiology and infection and pathology. More on molecular pathology. Thorough updating of the sections on pathology, immunology, pharmacology and immunology. Revision of all other chapters. More colour illustrations Comes with complete electronic version
“... Useful background information is displayed in blue boxes, and good use is made of numerous tables and diagrams... a useful book for the undergraduate medical or allied health professional...” –Oncology News, May/June 2010 This forward looking cancer biology book appeals to a wide ranging audience. Introductory chapters that provide the molecular, cellular, and genetic information needed to comprehend the material of the subsequent chapters bring unprepared students up to speed for the rest of the book and serve as a useful refresher for those with previous biology background. The second set of chapters focuses on the main cancers in terms of risk factors, diagnostic and treatment methods and relevant current research. The final section encompasses the immune system’s role in the prevention and development of cancer and the impact that the Human Genome Project will have on future approaches to cancer care. While best suited to non-majors cancer biology courses, the depth provided satisfies courses that combine both majors and non-majors. Also, and deliberately, the authors have incorporated relevant information on diagnosis and treatment options that lend appeal to the lay reader.
Providing a clear explanation of the relevant medical science behind the individual medical specialties, Basic Science for Core Medical Training and the MRCP, is an indispensable part of a candidate's MRCP preparation. Directly linked to the Royal College exam, the book follows the same systems-based approach as the syllabus for accurate and effective revision. With full coverage of basic science for the medical specialities, the book features material on genetics, cellular, molecular and membrane biology, and biochemistry. Content is presented in an illustrated and easy-to-read format, ensuring that the basic science for each medical specialty is more approachable and accessible. A focus on how the basic sciences aid understanding of clinical practice is reinforced through key tables of differential diagnoses and pharmacology. Ten multiple choice questions at the end of each chapter consolidate learning and enable candidates to test their knowledge. The book also covers common examination errors and areas of misunderstanding to aid learning and help candidates avoid common pitfalls.
Here is a complete resource for all the basic science and clinical knowledge related to otolaryngology, from relevant molecular biology to physiology to clinical practice. It offers excellent coverage of all key topics with one goal in mind — to provide a solid foundation for the understanding and practice of this diverse specialty. Both comprehensive and succinct, this book is an ideal review text and study tool for residents preparing for their board exams. Organized into six organ-specific sections, the book provides such key clinical information as: basic principles of allergic diseases, the oncology of head and neck tumors, the biology and testing of olfactory dysfunction, neurological disorders of the larynx, sleep apnea management, working with hearing aids and cochlear implants, and much more. Each chapter features a Chapter Outline, numerous tables, and Self-Test Questions with their answers to ensure thorough comprehension. You will also find more than 350 illustrations demonstrating important concepts. This book is an invaluable resource for residents taking their boards and a useful refresher for practicing otolaryngologists at all levels. It is the one reference you will turn to again and again.
This concise text examines cancer causation and biology as well as the biology underlying cancer treatment. Thoroughly updated and reorganized with five new chapters, the Fourth Edition emphasizes new development in molecular biology, hormone therapy, and the pharmacology of anti-cancer drugs. Features updated coverage of the basic science of radiotherapy and experimental radiation in addition to expansive coverage of new drugs developments.
The distinction between basic and applied research was central to twentieth-century science and policymaking, and if this framework has been contested in recent years, it nonetheless remains ubiquitous in both scientific and public discourse. Employing a transnational, diachronic perspective informed by historical semantics, this volume traces the conceptual history of the basic–applied distinction from the nineteenth century to today, taking stock of European developments alongside comparative case studies from the United States and China. It shows how an older dichotomy of pure and applied science was reconceived in response to rapid scientific progress and then further transformed by the geopolitical circumstances of the postwar era.
This textbook presents the most recent evidenced-based knowledge in basic sciences in anesthesia. It covers topics from the syllabus of the American Board of Anesthesiology (ABA) basic science exam, including anatomy, pharmacology, physiology, physics in anesthesia, and more. In each chapter, key points summarize the content, followed by a pertinent and concise discussion of the topic, ending with multiple choice questions with answers and suggested further reading. Basic Sciences in Anesthesia is aimed at residents taking the ABA basic science of anesthesia examination, and any other anesthesiologist or trainee with an interest in the topic.
Accompanying CD-ROM contains exactly the same information as the book.
The fifth edition of Orthopaedic Basic Science: Foundations of Clinical Practice is your concise and clinically relevant resource for the diagnosis and treatment of musculoskeletal diseases and conditions. This completely rewritten edition explains the functions and limitations of the science behind the decisions, treatments, and proc