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Fluorodeoxyglucose (FDG) has proven benefits as a positron emission tomography (PET) radiopharmaceutical in oncology. However, it has limitations in the assessment of certain tumours, above all (but not only) prostate cancer. Therefore, several non-FDG PET radiopharmaceuticals have been introduced into the clinical arena over the last few years, and this trend will continue to spread. The use of PET/CT with different PET radiopharmaceuticals that tailor to the type of tumour and biologic process that needs to be assessed is part of personalized precision medicine. The objective of this publication is to provide a case-based way of understanding normal biodistribution, variants, and pitfalls, including several examples of typical patterns for the main indications for each of the new non-FDG PET radiopharmaceuticals. This should facilitate the interpretation of images to support accurate diagnosis. This Atlas will allow professionals interested in non-FDG PET/CT imaging to embrace the variety of oncological imaging by providing clinically relevant teaching files on the effectiveness and diagnostic quality of non-FDG-PET/CT imaging in routine applications.
Fluorodeoxyglucose (FDG) has proven benefits as a positron emission tomography (PET) radiopharmaceutical in oncology.
The Atlas of PET/CT Imaging in Oncology serves an educational purpose and is designed to teach radiologists and nuclear medicine specialists about important aspects of molecular imaging and nuclear medicine specialists about the benefits of anatomic imaging. It consists of a brief didactic portion and an extensive selection of interesting and challenging case examples. A special feature of the atlas is an interactive CD-ROM that provides the original PET and CT images of each case in selected planes enabling the users to manually adjust the blending intensity of each modality in a fused image. In addition, users can display the clinical history, imaging techniques and diagnostic findings of each case as well as the corresponding specific teaching point.
Positron emission tomography/computed tomography (PET/CT), as any other imaging modality, is acceptable for routine clinical and research applications only if technical pitfalls can be avoided. Artefacts from incorrect or sub-optimal acquisition procedures should be recognized and, if possible, corrected retrospectively and the resulting image information interpreted correctly, which entails an appreciation of variants of the represented image information. This publication provides guidance on the physics and technical aspects behind PET and PET/CT image distortions. Cases are presented to provide nuclear medicine and radiology professionals with an assortment of examples of possible image distortions and errors in order to support a correct image interpretation. Nearly 70 typical PET and PET/CT cases, comprising image sets and cases, have been collected in this volume, all catalogued and augmented with explanations as to the causes of, and solutions to, each individual image problem. The atlas will prove useful to physicists, physicians, technologists, and service engineers in the clinical field.
Atlas of Diagnostic Oncology, 4th Edition, by Arthur T. Skarin, MD, FACP, FCCP, provides the guidance you need to diagnose a full range of neoplastic conditions with greater accuracy for better patient outcomes. An unrivaled collection of more than 2,500 images and drawings—combined with succinct, clinically focused text—equips you with essential information on pathology, diagnostic studies, staging, and clinical manifestations. New discussions on modern diagnostic PET imaging of cancer, and expanded coverage on the side effects of chemotherapy, bring you up to date on the issues impacting research and treatment. Expert Consult functionality—new to this edition—further enhances your reference power with convenient online access to the complete contents of the text, along with case studies that demonstrate effective approaches to diagnosis. A superb collection of more than 2,500 images encompasses the full spectrum of pathologic and radiologic studies, staging, and clinical manifestations, highlighting the pathologic anatomy of common clinical entities. A consistent chapter organization covers each disease’s incidence, epidemiology, etiology, and histopathology — as well as molecular biology, clinical features, diagnostic studies, and current clinical and pathologic staging — providing all the assistance you need to evaluate and monitor your patients effectively. This unique pictorial resource is a superb complement to treatment handbooks and major oncological texts. Expert Consult functionality provides online access to the complete text, fully searchable, with illustrations downloadable for your personal presentations, and case studies keyed to the book, at expertconsult.com. Completely updated chapters covering the newest genetic markers, imaging modalities, and pathologic techniques enable you to get the best results from today’s diagnostic tools. An expanded chapter on evaluating the side effects of chemotherapy, with additional images of reactions to the newest regimens, alerts you to potential common and uncommon side effects. Two new chapters address the complications of cancer and modern use of diagnostic PET scans, keeping you up to date on these hotly debated topics in the oncology community. A third new chapter covers malignant mesothelioma of the lung, plus other sites. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.
Completely updated to reflect the latest developments in science and technology, the second edition of this reference presents the diagnostic imaging tools essential to the detection, diagnosis, staging, treatment planning, and post-treatment management of cancer in both adults and children. Organized by major organs and body systems, the text offers comprehensive, abundantly illustrated guidance to enable both the radiologist and clinical oncologist to better appreciate and overcome the challenges of tumor imaging. Features 12 brand-new chapters that examine new imaging techniques, molecular imaging, minimally invasive approaches, 3D and conformal treatment planning, interventional techniques in radiation oncology, interventional breast techniques, and more. Emphasizes practical interactions between oncologists and radiologists. Includes expanded coverage of paediatric tumours as well as thorax, gastrointestinal tract, genitourinary, and musculoskeletal cancers. Offers reorganized and increased content on the brain and spinal cord. Nearly 1,400 illustrations enable both the radiologist and clinical oncologist to better appreciate and overcome the challenges of tumour imaging. - Outstanding Features! Presents internationally renowned authors' insights on recent technological breakthroughs in imaging for each anatomical region, and offers their views on future advances in the field. Discusses the latest advances in treatment planning. Devotes four chapters to the critical role of imaging in radiation treatment planning and delivery. Makes reference easy with a body-system organisation.
This atlas showcases cross-sectional anatomy for the proper interpretation of images generated from PET/MRI, PET/CT, and SPECT/CT applications. Hybrid imaging is at the forefront of nuclear and molecular imaging and enhances data acquisition for the purposes of diagnosis and treatment. Simultaneous evaluation of anatomic and metabolic information about normal and abnormal processes addresses complex clinical questions and raises the level of confidence of the scan interpretation. Extensively illustrated with high-resolution PET/MRI, PET/CT and SPECT/CT images, this atlas provides precise morphologic information for the whole body as well as for specific regions such as the head and neck, abdomen, and musculoskeletal system. Atlas and Anatomy of PET/MRI, PET/CT, AND SPECT/CT, Second Edition is a unique resource for physicians and residents in nuclear medicine, radiology, oncology, neurology, and cardiology.
This user-friendly atlas, featuring about 500 images, should be a quick guide to interpreting PET/CT images with FDG in oncology. It also illustrates how to recognize normal, para-physiological, and benign pathological uptakes in a case-based practical manner. The text, which includes most relevant technical and pathophysiological premises, covers the main clinical applications and clearly articulates learning points and pitfalls. This atlas aims to become a standard text for nuclear medicine physicians and radiologists, residents and technicians whose work involves PET/CT imaging. This book is also suitable for both undergraduate and postgraduate courses.
The field of nuclear medicine has evolved rapidly in recent years, and one very important aspect of this progress has been the introduction of hybrid imaging systems. PET-CT has already gained widespread acceptance in many clinical settings, especially within oncology, and now SPECT-CT promises to emulate its success. Useful applications of this new approach have been identified not only in oncology but also in endocrinology, cardiology, internal medicine, and other specialties. This atlas, which includes hundreds of high-quality images, is a user-friendly guide to the optimal use and interpretation of SPECT-CT. The full range of potential SPECT-CT applications in clinical routine is considered and assessed by acknowledged experts. The book is designed to serve as a reference text for both nuclear physicians and radiologists; it will also provide fundamental support for radiographers, technologists, and nuclear medicine and radiology residents.