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Rapidly increasing aging population and environmental stressors are the two main global concerns of increasing incidence of a variety of pathologies in the modern society. The complex etiologies and pathologies cause major challenges to disease treatment. On the other hand, several herbs are known for their health-caring and disease-curing activities. Ashwagandha, a popular herb in Indian traditional home medicine, Ayurveda, has gathered increasing recognition in recent years when the chemically synthesized drugs for single target therapies showed limited success and adverse toxic effects. Ashwagandha is known as a powerful adaptogen and trusted to enhance function of the brain, reproductive system, cell-mediated immunity and increase the body's defense against disease, and possess anti-inflammatory, anticancer and anti-arthritic activities. In this book, for the first time, we provide a complete portrait on scientific understanding of the effects of Ashwagandha and its active principles for a variety of preventive and therapeutic activities.
Access to accurate, evidence-based, and clinically relevant information is essential to anyone who uses or recommends herbal products. With input from some of the most respected experts in herbal and integrative medicine, this completely revised edition of the American Herbal Products Association’s Botanical Safety Handbook reviews both traditional knowledge and contemporary research on herbs to provide an authoritative resource on botanical safety. The book covers more than 500 species of herbs and provides a holistic understanding of safety through data compiled from clinical trials, pharmacological and toxicological studies, medical case reports, and historical texts. For each species, a brief safety summary is provided for quick reference, along with a detailed review of the literature. Easily understood classification systems are used to indicate the safety of each listed species and the potential for the species to interact with drugs. Enhancements to the Second Edition include: Classification of each herb with both a safety rating and a drug interaction rating More references listed for each individual herb, vetted for accuracy Specific information on adverse events reported in clinical trials or case reports Safety-related pharmacology and pharmacokinetics of each herb, including drug interactions Additional information on the use of herbs by pregnant or lactating women Toxicological studies and data on toxic compounds Representing the core of the botanical trade and comprising the finest growers, processors, manufacturers, and marketers of herbal products, the mission of the AHPA is to promote the responsible commerce of herbal products. The American Herbal Products Association Botanical Safety Handbook, Second Edition ensures that this vision is attained. The book will be a valuable reference for product manufacturers, healthcare practitioners, regulatory agencies, researchers, and consumers of herbal products.
Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Adaptogens help the body to "adapt" to the many health challenges it encounters--particularly stress. They increase stamina and counter the effects of aging and thus are becoming important tools in sports medicine and in the prevention and treatment of chronic fatigue and related disorders. The authors explain how they work and why they are so effective at combating stress-induced illness.
A practical and delicious field guide to cooking and healing with adaptogens from wellness expert and former chef Amanda Chantal Bacon, founder of Moon Juice and author of The Moon Juice Cookbook In The Moon Juice Manual, Amanda Chantal Bacon lays out the blueprint for the next level of mind-body health. This is the quintessential guide to adaptogens, the stress-busting super-herbs and -mushrooms that Bacon introduced to the wellness world with her cult-followed Moon Dust collection. As the name suggests, adaptogens are plants that can help us adapt to and protect ourselves from the daily stress of modern life. From cordyceps (a mushroom to elevate energy and libido) to ashwagandha (a shrub to tame anxiety and reduce inflammation), adaptogens are a powerful, edible antidote to today's stressed-out, high-speed world. A plant-fueled survival guide to modern life, The Moon Juice Manual explains the way chronic stress impacts the mind and body and provides simple and delicious ways to incorporate adaptogens into daily life. The book offers prescriptive recommendations and functional recipes for optimizing beauty, brain, spirit, sex, sleep, or mood. Readers will understand how to make grain-free and practical recipes with adaptogens along with easy, decadent treats like Horny Goat Weed Brownies and Schisandra Sleeping Beauty Balls. The Moon Juice Manual makes cooking and healing with adaptogens fun, approachable, and truly transformative.
In the tradition of the bestselling Alchemy of Herbs, The Complete Guide to Adaptogens details the benefits of twenty-four adaptogenic herbs, and includes more than seventy-five recipes that target specific wellness categories such as sleep, mental focus, beauty—and more! Adaptogens are a unique class of herbs that greatly improve your body's reaction to emotional and physical stress, while also increasing your energy, stamina, endurance, and mental clarity. Recent studies support what practitioners of Indian Ayurveda and traditional Chinese medicine have known for centuries—these herbs such as Rhodiola, ginseng, licorice, and more, have many heath and wellness benefits and are safe for long-term use. Whether you're interested in honing your mental abilities to a razor-sharp level, want to boost your athleticism, or are looking for ways to elevate your healthy lifestyle, adaptogens have so much to offer for everyday well-being. In The Complete Guide to Adaptagens, you'll learn about the numerous benefits of twenty-four popular adaptogenic herbs, including Rhodiola, Ashwagandha, Maca, He Shou Wu, and Holy Basil. You'll also find more than seventy-five easy recipes for potions and remedies to improve sleep, mood, mental focus, immune function, stamina, as well as general wellness and beauty. These all-natural, safe remedies fight the effects of chronic stress, while restoring your body’s balance, health, and vitality.