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The filamentous fungi are perhaps unique in the diversity of their metabolic activities. This includes biosynthetic as well as degradative activities, many is to provide an of which are of industrial interest. The objective of this text up-to-date and broad review which emphasizes the genetic and molecular biological contribution in the field of fungal biotechnology. This text begins with an overview of the tools and methodologies involved which, to a large extent, have been developed in the model filamentous fungus Aspergillus nidulans and subsequently have been extended to commercially important fungi. This is followed by a chapter which provides a compilation of genes isolated from commercial fungi and their present status with respect to structure, function and regulation. Chapters 3 and 4 highlight the degradative powers of filamentous fungi. First, a discussion of what is known regarding the molecular genetics of fungi and the genes and enzymes involved in the beverage and food industries. This has an oriental flavour, reflecting the tremendous importance of fungi in traditional Chinese and Japanese food production. An account of lignocellulose degradation by filamentous fungi follows, illustrating the potential of fungi to utilize this substance as a renewable energy source. The ability of fungi to produce high-value foreign proteins is reviewed in chapters 5 and 6. Chymosin production, in particular, represents a good example of high-level yields being obtained, such as to warrant commercial production.
The interactions of fungi with mankind are both beneficial and harmful and are deeply rooted in the history of human society and agriculture. This book highlights the ways in which fungal recombinant DNA technology is being used in species of economic importance.
This is a concise guide to the combined use of classical and molecular methods for the genetic analysis and breeding of fungi. It presents basic concepts and experimental designs, and demonstrates the power of fungal genetics for applied research in biotechnology and phytopathology. Case studies of Saccharomyces cerevisiae, Candida albicans, Aspergillus niger, Neurospora crassa, Podospora anserina, Phytophthora infestans and others are included.
An ideal starting point for any research study of filamentous fungi. • Incorporates the latest findings from such disciplines as physiology, taxonomy, genomics, molecular biology and cell biology. • Begins with an historical perspective, cell morphology and taxonomy, and moves on to such topics as cell growth, development, metabolism, and pathogenesis. • Presents the full range of the fungal kingdom and covers important topics as saprophytes, pathogens and endophytes. • Serves as a recommended text for graduate and undergraduate students.
Keywords: Fungi, biotechnology, fungal molecular biology, molecular genetics, mycology, yeast.
This volume brings together detailed practical guidance from experienced researchers using genetic, genomic, cellular and biochemical methods, to attempt to determine the functions of genes and how they contribute to the biology of fungi.
The book gives an overview of the state-of-the-art in major fields of research in modern fungal genetics. Focus has been placed on the two most fascinating aspects of this rapidly expanding field: * Molecular Biology of Pathogenetic Fungi: Molecular techniques available for these fungi have yielded new and intriguing approaches to studying host/pathogen interactions. An example of worldwide relevance: the potential implementation of fungi as insecticides. * Gene Expression in Fungal Systems: This includes the fundamental aspects of regulation and differentiation as well as the applied aspects of using these fungi in biotechnological processes. An example of industrial relevance: the production of antibiotics using fungi. Scientists and advanced students in the areas of fungal genetics, phytopathology and biotechnology will find this book to be an indispensable summary of recent advances and an invaluable stimulus for their research.
Ten articles provide an overview of the recently flowering research into the genetics and molecular biology of fungus species that are economically significant in industry. The contributors, from a variety of disciplines, report on work in such areas as industrial enzymes, antibiotics, toxins, heter
This volume focuses on filamentous fungi and highlights the advances of the past decade, both in methodology and in the understanding of genomic organization and regulation of gene and pathway expression. The approaches and techniques of molecular biology enable us to ask and answer fundamental questions about many aspects of fungal biology, and open the way to the directed manipulation of fungal genetics. Moreover, this book describes the development and advancement of fungal genes and the ways in which these are being exploited in species of economic importance either in biotechnology or in biochemistry.