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My little one, lay down your head.It's time to doze, it's time for bed.You tell me, "I'm not sleepy now.""Just try," I say. You ask me, "How?" In this lyrical animal ABC book, a mother tries to tuck her child in for the night by telling him about all the awake animals that are getting sleepy. From antlered Antelope to zzz-ing Zebra, this alphabet of animals becomes an exquisite celebration of language and nature, just right for lulling even the most wide-awake little ones into a cozy, soothing slumber.
Little ones find nocturnal animals under peep-through flaps, and explore the night-time world in different habitats and seasons. Who's wide awake while you're fast asleep? Go on an exciting night-time journey and find delightful nocturnal animals hiding under peek-through flaps. Toddlers will love exploring different habitats and seasons at night, and finding out about nature and wildlife in this beautifully illustrated, read-aloud board book. The intriguing cover has cutaway stars to feel, and inside, there are adorable sleeping animals and hidden nocturnal animals - under large flaps with peek-through holes. As the moon shines brightly, many animals and people sleep - from children dreaming in their beds to squirrels curled up in their nests and butterflies resting amongst the leaves. But who is not asleep? Take a peep! Take a peep! Lift the flaps and discover the sharp-eyed cat outside the window, fluffy owlets in a tree, cuddly koalas in the outback, twinkling fireflies in the park, foxes in the snowy woods, and more! Flip Flap Find! Night-time Animals is a captivating picture book to share. A perfect gift for little nature lovers, it will spark a toddler's curiosity, stimulate their imagination, language, and literacy, and build their knowledge of the natural world.
An explanation of why animals behave in unusual ways prior to the onset of an earthquake.
An updated edition of Moorcroft’s 2003 volume, this new work reflects recent scientific advances in the area of sleep and disorders. As in the previous book, Understanding Sleep and Dreaming, this new edition serves as a compact overview for now sleep experts, covering physiological sleep mechanisms, brain function, psychological ramifications of sleep, dimensions of dreaming, and clinical disorders associated with sleep. It is accessibly written with specially boxed material that enhances the text. It also offers a good foundation for those who will continue sleep studies, while at the same time offering enough information for those who will apply this knowledge in other ways such as clinicians private practices or researchers. It is an excellent text for courses on sleep at the undergraduate and graduate levels. The section on sleep labs will show how computers have replaced former models of data collection and storage; includes the new area of the genetics of sleep; add a new box on teen sleep; insert a new box on the emerging information about how technology use affects sleep; emphasize the controversy over rampart, wide-spread sleep deprivation; and include a new box covering the connection between sleep loss and weight gain. Additional inclusions might incorporate current “hot topics,” such as the effect of shift work on sleep, sleep problems in adolescents, and nightmare treatment for people suffering from PTSD.
A bedtime picture book favorite now available as an adorable board book! Something’s out there in the dark! First Possum hears it. Then Skunk. Then Wolf comes running. “What could it possibly be?” asks Bat. “Night Animals!” the animals declare. “But you are night animals,” Bat informs this not-so-smart crew. Children will love the oh-so-funny animals in this twist on a cozy bedtime book.
The new edition of Gray's acclaimed text, featuring dramatic new coverage of sensation and perception and new media tools that actively involve students in psychological research.
This volume traces the modern critical and performance history of this play, one of Shakespeare's most-loved and most-performed comedies. The essay focus on such modern concerns as feminism, deconstruction, textual theory, and queer theory.
Animal and Translational Models for CNS Drug Discovery combines the experience of academic, clinical and pharmaceutical neuroscientists in a unique collaborative approach to provide a greater understanding of the relevance of animal models of neuropsychiatric disorders and their role as translational tools for the discovery of CNS drugs being developed for the treatment of these disorders. The focus of this three-volume series of essays is to present a consensual picture of the translational value of animal models from leading experts actively involved in the use of animal models for understanding fundamental neurobiology of CNS disorders and the application of this knowledge to CNS drug discovery, and clinical investigators involved in clinical trials, drug development and eventual registration of novel pharmaceuticals. Each volume of the Animal and Translational Models for CNS Drug Discovery series is dedicated to the development and use of animal models in key therapeutic areas in psychiatric, neurologic and reward deficit disorders. Each volume has introductory chapters expressing the view of the role and relevance of animal models for CNS drug discovery and development from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in relevant therapeutic areas and discusses the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. - Provides clinical, academic, government and industry perspectives fostering integrated communication between principle participants at all stages of the drug discovery process - Critical evaluation of animal and translational models improving transition from drug discovery and clinical development - Emphasizes what results mean to the overall drug discovery process - Explores issues in clinical trial design and conductance in each therapeutic area - Each volume is available for purchase individually.
Aristotle’s Parva naturalia continues the investigation begun in the De anima. The De anima defines the soul and treats its main powers, nutrition, sense perception, intellection, and locomotion. The Parva naturalia — On sense and sensible objects, On memory and recollection, On sleep, On dreams, On divination in sleep, On motion of animals (De motu animalium ), On length and shortness of life, and On youth and old age and respiration — attends more to bodily involvement with soul. While each work offers fascinating and challenging insights, there has never been as extensive a commentary covering them together. A reason is that the works have often been viewed as incidental and even inconsistent. The De motu animalium has not typically been included, when viewed as an isolated work on animal locomotion. This commentary argues that the treatises, considered together and with the De motu among them, display a tight sequence manifesting an artful, yet easily overlooked, design. We reveal many techniques of Aristotle’s writing that have received little consideration previously. Our commentary contributes to a unified and comprehensive account of Aristotle’s overall project regarding the soul and its connections with the body.
Psychiatric Disorders is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for psychiatric disorders such as anxiety, obsessive-compulsive disorder, depression, schizophrenia, bipolar disorder, ADHD, and autistic spectrum disorder. Psychiatric Disorders has introductory chapters expressing the view of the role and relevance of animal models for drug discovery and development for the treatment of psychiatric disorders from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in each therapeutic area covered and discuss the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This is the first volume in the three volume-set, Animal and Translational Models for CNS Drug Discovery 978-0-12-373861-5, and is also available for purchase individually. - Provides clinical, academic, government and industry perspectives fostering integrated communication between principle participants at all stages of the drug discovery process - Critical evaluation of animal and translational models improving transition from drug discovery and clinical development - Emphasizes what results mean to the overall drug discovery process - Explores issues in clinical trial design and conductance in each therapeutic area - Psychiatric Disorders is available for purchase individually.