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By presenting background information on the selection and application of biochemical tests in safety assessment studies, this text seeks to provide a basis for improving the knowledge required to interpret data from toxicological studies. In addition to chapters which discuss the assessment of specific organ toxicity (such as the liver, kidney and thyroid), the book also covers pre-analytical variables, regulatory requirements and statistical approaches, and highlights some of the major differences between man and different laboratory animals. The editor and contributor are all members of the Animal Clinical Chemistry Association, a group formed to advance the science of animal clinical chemistry in safety evaluation, toxicology and veterinary science.
This title provides veterinary students and non-specialist with a case study base workbook which serves as a guide to effective use and interpretation of clinical chemistry laboratory methods in domestic animals. There are over 100 case studies involving real patients and findings in dogs, cats, horses, lamas, alpacas, pot belled pigs and ferrets. Case studies consist of patient history, physical examination findings, and clinicopthologic data such as CBC, urinalysis, cytology or fluid analysis. A summary is given for each patient that includes a description of follow up tests and response to treatment. Multiple cases of common diseases are included to illustrate the variety of clinciopathologic findings with the same diagnosis depending on individual patient factors. Diagnostic dilemmas in which different diseases may present with similar clinical signs and laboratory data are also included. Published by Teton New Media in the USA and distributed by Manson Publishing outside of North America.
This guide provides an easy-to-use desk reference for diagnostic information on commonly used hematology, clinical chemistry and urinalysis parameters. Additional reference materials are provided as an aid in evaluating clinical pathology data. For many toxicologists, the evaluation of hematology, clinical chemistry and urinalysis data can be the most challenging aspect of animal toxicity studies. In a typical toxicity study, dozens of parameters are measured several times over the course of the study. There may be hundreds of data points, each of which needs to be considered. A Toxicologist’s Guide to Clinical Pathology in Animals will serve as an essential primer for toxicologists in training and in industry as well as for researchers and professionals in a veterinary practice or a laboratory.
This book, edited in partnership with the American College of Laboratory Medicine (ACLAM), is the most comprehensive reference available on in vivo animal studies as a critical part of biomedical research. It covers relevant laboratory animal species, specific organ systems and important classes of analytes.
This reference on veterinary haematology and clinical chemistry is designed to be both comprehensive and practical. From basic principles and laboratory techniques to diagnostic evaluation, readers will find equally concise and clear coverage of both haematology and clinical chemistry for many domestic and exotic species. It also features numerous four-colour and black-and-white illustrations, coverage of avian and exotic haematology and an extensive use of case studies.
Clinical Biochemistry of Domestic Animals, Second Edition, Volume I, is a major revision of the first edition prompted by the marked expansion of knowledge in the clinical biochemistry of animals. In keeping with this expansion of knowledge, this edition is comprised of two volumes. Chapters on the pancreas, thyroid, and pituitary-adrenal systems have been separated and entirely rewritten. Completely new chapters on muscle metabolism, iron metabolism, blood clotting, and gastrointestinal function have been added. All the chapters of the first edition have been revised with pertinent new information, and many have been completely rewritten. This volume contains 10 chapters and opens with a discussion of carbohydrate metabolism and associated disorders. Separate chapters follow on lipid metabolism, plasma proteins, and porphyrins. Subsequent chapters deal with liver, pancreatic, and thyroid functions; the role of the pituitary and adrenal glands in health and disease; the function of calcium, inorganic phosphorus, and magnesium metabolism in health and disease; and iron metabolism.
A quick guide to appropriately selecting and interpreting laboratory tests, Small Animal Clinical Diagnosis by Laboratory Methods, 5th Edition helps you utilize your in-house lab or your specialty reference lab to efficiently make accurate diagnoses without running a plethora of unnecessary and low-yield tests. It provides answers to commonly asked questions relating to laboratory tests, and solutions to frequently encountered problems in small animal diagnosis. For easy reference, information is provided by clinical presentation and abnormalities, and includes hundreds of tables, boxes, key points, and algorithms. This edition, now in full color, is updated with the latest advances in laboratory testing methods and diagnostic problem solving. Written by noted educators Dr. Michael Willard and Dr. Harold Tvedten, this book may be used as an on-the-spot guide to specific problems or conditions as well as a reference for more detailed research on difficult cases. - Concise discussions address laboratory approaches to various disorders, possible conclusions from various test results, artifacts and errors in diagnoses, and interpretations leading to various diagnoses. - Hundreds of tables, boxes, algorithms, and key points offer at-a-glance information including cautions, common pitfalls, and helpful "pearls," and lead to proper differential and clinical diagnostic decision making. - Note boxes identify key considerations in correlating clinical signs with test data for accurate diagnoses, highlight safety precautions, and offer helpful tips for sample preparation and interpretation. - Chapters on laboratory diagnostic toxicology and therapeutic drug monitoring help in handling potentially fatal poisonings and other special situations. - Expert editors and contributors provide clinical knowledge and successful diagnostic problem-solving solutions. - A practical appendix lists referral laboratories that may be contacted for certain diseases, and reference values with the normal or expected range for coagulation, hematology, and more. - Updated coverage integrates the newest advances in testing methods and diagnostic problem solving. - Full-color photos and schematic drawings are placed adjacent to related text, and accurately depict diagnostic features on microscopic slide preparations as well as test procedures and techniques.
Clinical Pathology for the Veterinary Team is a concise, reliable resource for technical team members performing clinical diagnostic evaluation. Focusing on sample handling, machinery calibration, normal physiology and anatomy, clinical diagnostics, and disease processes, this essential bench-side reference for in-house laboratories helps technical team members to consistently achieve high-quality results in small animal lab work. With chapters on blood counts, chemistry, urinalysis and electrolytes, advanced diagnostics, and cytology, Clinical Pathology for the Veterinary Team offers key technical information for consistently obtaining and evaluating samples. The book is a practical resource for anyone performing lab work, including veterinary technicians, technician and veterinary students, and veterinarians.
Provides the information needed to interpret clinical laboratory assays of domestic mammals Fundamentals of Veterinary Clinical Pathology, Third Edition presents thoroughly updated and detailed information to promote appropriate clinical laboratory testing and interpretation of test results for common domestic mammals. Presented in an easy-to-use outline format complemented by many relevant tables and illustrations, the book is now in full color. This evidence-based guide synthesizes the laboratory principles, physiology, assays, analytical concepts, pathophysiologic states, and pathophysiologic processes relevant to detecting, evaluating, and understanding disorders in dogs, cats, horses, cattle, and camelids. Content additions include two entirely new chapters on synovial and cerebrospinal fluid analysis, as well as expanded sections on blood typing and crossmatching, viscoelastic testing, protein electrophoresis, positive acute-phase proteins, mixed acid-base disorders, vitamin D analysis, analytical and biological variation, blood smear evaluation, and more. New clinical tests and methods, useful data patterns, and additional disorders and pathologic processes are integrated throughout. Providing a conceptual understanding applicable to many species and serving as a valuable clinical reference, Fundamentals of Veterinary Clinical Pathology: Uses consistent terminology and chapter organization featuring separate sections for physiologic concepts, analytical methods, and interpretation of results Provides pathophysiologic explanations of laboratory abnormalities Allows easy access to information on disorders and conditions, grouping them by common mechanisms or processes and ordering them in parallel across interpretive tables and text Features a wealth of high-quality illustrations and photomicrographs throughout the text Includes extensive referencing on the companion website to support statements and provide direction for further reading Fundamentals of Veterinary Clinical Pathology, Third Edition is an excellent textbook for veterinary students taking clinical pathology courses, as well as a valuable resource for clinical and anatomic pathology residents, medicine and surgery residents, and practicing veterinarians.
Clinical Pathology and Laboratory Techniques for Veterinary Technicians provides a comprehensive reference of laboratory procedures featuring ‘how-to’ information as it pertains to small animals, horses, and cattle. An inclusive reference on laboratory procedures pertaining to small animals, horses and cattle Provides information on hematology, hemostasis, clinical chemistry, urinalysis, parasitology, and fecal testing Features high-quality photographs labelled with magnification and stain information, which clearly depict cellular morphology, inclusions and infectious organisms Offers key objectives, technician tip boxes, case examples and a glossary of key terms A companion website provides images from the book for download, instructor questions and answer key to multiple choice questions in the book