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Researchers often do not analyze nonreplicated experiments statistically because they are unfamiliar with existing statistical methods that may be applicable. Analysis of Messy Data, Volume II details the statistical methods appropriate for nonreplicated experiments and explores ways to use statistical software to make the required computations feasible.
Analysis of covariance is a very useful but often misunderstood methodology for analyzing data where important characteristics of the experimental units are measured but not included as factors in the design. Analysis of Messy Data, Volume 3: Analysis of Covariance takes the unique approach of treating the analysis of covariance problem by looking
A bestseller for nearly 25 years, Analysis of Messy Data, Volume 1: Designed Experiments helps applied statisticians and researchers analyze the kinds of data sets encountered in the real world. Written by two long-time researchers and professors, this second edition has been fully updated to reflect the many developments that have occurred since t
Researchers often do not analyze nonreplicated experiments statistically because they are unfamiliar with existing statistical methods that may be applicable. Analysis of Messy Data, Volume II details the statistical methods appropriate for nonreplicated experiments and explores ways to use statistical software to make the required computations feasible.
Researchers often do not analyze nonreplicated experiments statistically because they are unfamiliar with existing statistical methods that may be applicable. Analysis of Messy Data, Volume II details the statistical methods appropriate for nonreplicated experiments and explores ways to use statistical software to make the required computations feasible.
Systematic treatment of the commonly employed crossed and nested classification models used in analysis of variance designs with a detailed and thorough discussion of certain random effects models not commonly found in texts at the introductory or intermediate level. It also includes numerical examples to analyze data from a wide variety of disciplines as well as any worked examples containing computer outputs from standard software packages such as SAS, SPSS, and BMDP for each numerical example.
Failure modes and effects analysis (FMEA); Reliability; Product Development; Design Process; Test Procedures "Explore Product Design and Testing for Automotive Engineering: Volume II, an essential guide reshaping vehicle manufacturing with unprecedented reliability. As part of SAE International’s DOE for Product Reliability Growth series, this practical resource introduces cutting-edge methodologies crucial for predicting and improving product reliability in an era of automotive electrification. The book navigates statistical tolerance design, showcasing how variability in part fabrication and assembly can enhance reliability and sustainability. Key topics include: - Statistical tolerance design's impact on manufacturing and material selection, focusing on non-normal distributions' effects on product assembly and cost. Methods like maximum likelihood estimators and Monte Carlo simulations are used for assembly strategy synthesis. - Reliability DOEs using log-location-scale distributions to estimate lifetimes of non-normally distributed components, especially in accelerated life testing. It covers transformations optimizing parts and system designs under the lognormal distribution. - Weibull distribution (DOE-W) for characterizing lifetimes affected by various failure modes, detailing parameter assessment methods and real-world applications. The book also introduces reliability design of experiments based on the exponential distribution (DOE-E). - Importance of predicting lifecycles and enhancing reliability through qualitative and stepwise accelerated life tests. Integration of physics of failure with statistical methods like Weibull statistics and lognormal approximation enhances analysis credibility. - Inferential mechanisms such as the Arrhenius and Eyring models in predicting automotive component lifecycles, refining product life prediction based on reliability DOEs. Whether you're an engineer, researcher, or automotive professional, this book equips you to navigate reliability engineering confidently. Revolutionize your approach to product design and testing with Product Design and Testing for Automotive Engineering, your definitive companion in shaping the future of automotive reliability." (ISBN 9781468607703 ISBN 9781468607697 ISBN 9781468607727 DOI 10.4271/9781468607697)
Developing Solid Oral Dosage Forms is intended for pharmaceutical professionals engaged in research and development of oral dosage forms. It covers essential principles of physical pharmacy, biopharmaceutics and industrial pharmacy as well as various aspects of state-of-the-art techniques and approaches in pharmaceutical sciences and technologies along with examples and/or case studies in product development. The objective of this book is to offer updated (or current) knowledge and skills required for rational oral product design and development. The specific goals are to provide readers with: - Basics of modern theories of physical pharmacy, biopharmaceutics and industrial pharmacy and their applications throughout the entire process of research and development of oral dosage forms - Tools and approaches of preformulation investigation, formulation/process design, characterization and scale-up in pharmaceutical sciences and technologies - New developments, challenges, trends, opportunities, intellectual property issues and regulations in solid product development - The first book (ever) that provides comprehensive and in-depth coverage of what's required for developing high quality pharmaceutical products to meet international standards - It covers a broad scope of topics that encompass the entire spectrum of solid dosage form development for the global market, including the most updated science and technologies, practice, applications, regulation, intellectual property protection and new development trends with case studies in every chapter - A strong team of more than 50 well-established authors/co-authors of diverse background, knowledge, skills and experience from industry, academia and regulatory agencies
Two critical questions arise when one is confronted with a new problem that involves the collection and analysis of data. How will the use of statistics help solve this problem? Which techniques should be used? Statistics for Environmental Engineers, Second Edition helps environmental science and engineering students answer these questions when the goal is to understand and design systems for environmental protection. The second edition of this bestseller is a solutions-oriented text that encourages students to view statistics as a problem-solving tool. Written in an easy-to-understand style, Statistics for Environmental Engineers, Second Edition consists of 54 short, "stand-alone" chapters. All chapters address a particular environmental problem or statistical technique and are written in a manner that permits each chapter to be studied independently and in any order. Chapters are organized around specific case studies, beginning with brief discussions of the appropriate methodologies, followed by analysis of the case study examples, and ending with comments on the strengths and weaknesses of the approaches. New to this edition: Thirteen new chapters dealing with topics such as experimental design, sizing experiments, tolerance and prediction intervals, time-series modeling and forecasting, transfer function models, weighted least squares, laboratory quality assurance, and specialized control charts Exercises for classroom use or self-study in each chapter Improved graphics Revisions to all chapters Whether the topic is displaying data, t-tests, mechanistic model building, nonlinear least squares, confidence intervals, regression, or experimental design, the context is always familiar to environmental scientists and engineers. Case studies are drawn from censored data, detection limits, regulatory standards, treatment plant performance, sampling and measurement errors, hazardous waste, and much more. This revision of a classic text serves as an ideal textbook for students and a valuable reference for any environmental professional working with numbers.
This text is divided into three parts. The first part describes basic toxicological concepts and methodologies used in aquatic toxicity testing, including the philosophies underlying testing strategies now required to meet and support regulatory standards. The second part of the book discusses various factors that affect transport, transformation, ultimate distribution, and accumulation of chemicals in the aquatic environment, along with the use of modelling to predict fate.; The final section of the book reviews types of effects or endpoints evaluated in field studies and the use of structure-activity relationships in aquatic toxicology to predict biological activity and physio-chemical properties of a chemical. This section also contains an extensive background of environmental legislation in the USA and within the European Community, and an introduction to hazard/risk assessment with case studies.