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This book illustrates the computational framework based on knowledge of flow and mass transfer together with optimization techniques to solve problems relevant to micromixing technology. The authors provide a detailed analysis of the different numerical techniques applied to the design of micromixers. Flow and mixing analysis is based on both the Eulerian and Lagrangian approaches; relative advantages and disadvantages of the two methods and suitability to different types of mixing problems are analysed. The book also discusses the various facets of numerical schemes subjected to discretization errors and computational grid requirements. Since a large number of studies are based on commercial computational fluid dynamics (CFD) packages, relevant details of these packages to the mixing problem using them are presented. Numerical optimization techniques coupled with CFD analysis of flow and mixing have proved to be an important tool for micromixers design, and therefore, are an important part of the book. These techniques are presented briefly, and focus is on surrogate modeling and optimization applied to design of micromixers.
This book includes an editorial and 12 research papers on micromixers collected from the Special Issue published in Micromachines. The topics of the papers are focused on the design of micromixers, their fabrication, and their analysis. Some of them proposed novel micromixer designs. Most of them deal with passive micromixers, but two papers report studies on electrokinetic micromixers. Fully three-dimensional (3D) micromixers were investigated in some cases. One of the papers applied optimization techniques to the design of a 3D micromixer. A review paper is also included and reports a review of recently developed passive micromixers and a comparative analysis of 10 typical micromixers.
The ability to mix minute quantities of fluids is critical in a range of recent and emerging techniques in engineering, chemistry and life sciences, with applications as diverse as inkjet printing, pharmaceutical manufacturing, specialty and hazardous chemical manufacturing, DNA analysis and disease diagnosis.The multidisciplinary nature of this field – intersecting engineering, physics, chemistry, biology, microtechnology and biotechnology – means that the community of engineers and scientists now engaged in developing microfluidic devices has entered the field from a variety of different backgrounds.Micromixers is uniquely comprehensive, in that it deals not only with the problems that are directly related to fluidics as a discipline (aspects such as mass transport, molecular diffusion, electrokinetic phenomena, flow instabilities, etc.) but also with the practical issues of fabricating micomixers and building them into microsystems and lab-on-chip assemblies.With practical applications to the design of systems vital in modern communications, medicine and industry this book has already established itself as a key reference in an emerging and important field.The 2e includes coverage of a broader range of fabrication techniques, additional examples of fully realized devices for each type of micromixer and a substantially extended section on industrial applications, including recent and emerging applications. - Introduces the design and applications of micromixers for a broad audience across chemical engineering, electronics and the life sciences, and applications as diverse as lab-on-a-chip, ink jet printing, pharmaceutical manufacturing and DNA analysis - Helps engineers and scientists to unlock the potential of micromixers by explaining both the scientific (microfluidics) aspects and the engineering involved in building and using successful microscale systems and devices with micromixers - The author's applied approach combines experience-based discussion of the challenges and pitfalls of using micromixers, with proposals for how to overcome them
The Sixth International Conference on Miniaturized Chemical and Biochemical Analysis Systems, known as /JTAS2002, will be fully dedicated to the latest scientific and technological developments in the field of miniaturized devices and systems for realizing not only chemical and biochemical analysis but also synthesis. The first /JTAS meeting was held in Enschede in 1994 with approximately 160 participants, bringing together the scientists with background in analytical and biochemistry with those with Micro Electro Mechanical Systems (MEMS) in one workshop. We are grateful to Piet Bergveld and Albert van den Berg of MESA Research Institute of the University of Twente for their great efforts to arrange this exciting first meeting. The policy of the meeting was succeeded by late Prof. Dr. Michael Widmer in the second meeting, /JTAS'96 held in Basel with 275 participants. The first two meetings were held as informal workshops. From the third workshop, /JTAS'98 (420 participants) held in Banff, the workshop had become a worldwide conference. Participants continued to increase in /JTAS2000 (about 500 participants) held in Enschede and /JTAS2001 (about 700 participants) held in Monterey. The number of submitted papers also dramatically increased in this period from 130 in 1998, 230 in 2000 to nearly 400 in 2001. From 2001, /JTAS became an annual symposium. The steering committee meeting held in Monterey, confrrmed the policy of former /JTAS that quality rather than quantity would be the key-point and that the parallel-session format throughout the 3.
This book presents the topology optimization theory for laminar flows with low and moderate Reynolds numbers, based on the density method and level-set method, respectively. The density-method-based theory offers efficient convergence, while the level-set-method-based theory can provide anaccurate mathematical expression of the structural boundary. Unsteady, body-force-driven and two-phase properties are basic characteristics of the laminar flows. The book discusses these properties, which are typical of microfluidics and one of the research hotspots in the area of Micro-Electro-Mechanical Systems (MEMS), providing an efficient inverse design approach for microfluidic structures. To demonstrate the applications of this topology optimization theory in the context of microfluidics, it also investigates inverse design for the micromixer, microvalve and micropump, which are key elements in lab-on-chip devices.
Microfluidics represent great potential for chemical processes design, development, optimization, and chemical engineering bolsters the project design of industrial processes often found in large chemical plants. Together, microfluidics and chemical engineering can lead to a more complete and comprehensive process. Process Analysis, Design, and Intensification in Microfluidics and Chemical Engineering provides emerging research exploring the theoretical and practical aspects of microfluidics and its application in chemical engineering with the intention of building pathways for new processes and product developments in industrial areas. Featuring coverage on a broad range of topics such as design techniques, hydrodynamics, and numerical modelling, this book is ideally designed for engineers, chemists, microfluidics and chemical engineering companies, academicians, researchers, and students.
Innovative Development in Micromanufacturing Processes details cutting edge technologies in micromanufacturing processes, an industry which has undergone a technological transformation in the past decade. Enabling engineers to create high performance, low cost, and long-lasting products, this book is an essential companion to all those working in micro and nano engineering. As products continue to get smaller and smaller, the field of micromanufacturing has gained an international audience. This book looks at both approaches of micromanufacturing: top-down and bottom-up. The top-down approach includes subtractive micromanufacturing processes such as microturning, micromilling, microdrilling, laser beam micromachining, and magnetic abrasive finishing. The bottom-up approach involves additive manufacturing processes such as micro-forming, micro deep drawing, microforging, microextrusion, and microwelding. Additionally, microjoining and microhybrid manufacturing processes are discussed in detail. The book also aids engineers and students in solving common manufacturing issues such as choice of materials and testing. The book will be of interest to those working in micro and nano engineering and machining, as well as students in manufacturing engineering, materials science, and more.
This book constitutes the refereed proceedings of the First International Conference on Biomedical Informatics and Technology, ACBIT 2013, held in Aizu-Wakamatsu, Japan, in September 2013. The ??? revised full papers presented together with 14 keynotes and invited talks were carefully reviewed and selected from 48 submissions. The papers address important problems in medicine, biology and health using image analysis, computer vision, pattern analysis and classification, information visualization, signal processing, control theory, information theory, statistical analysis, information fusion, numerical analysis, fractals and chaos, optimization, simulation and modeling, parallel computing, computational intelligence methods, machine learning, data mining, decision support systems, database integration and management, cognitive modeling, and applied linguistics.
This book, divided in two volumes, originates from Techno-Societal 2018: the 2nd International Conference on Advanced Technologies for Societal Applications, Maharashtra, India, that brings together faculty members of various engineering colleges to solve Indian regional relevant problems under the guidance of eminent researchers from various reputed organizations. The focus is on technologies that help develop and improve society, in particular on issues such as the betterment of differently abled people, environment impact, livelihood, rural employment, agriculture, healthcare, energy, transport, sanitation, water, education. This conference aims to help innovators to share their best practices or products developed to solve specific local problems which in turn may help the other researchers to take inspiration to solve problems in their region. On the other hand, technologies proposed by expert researchers may find applications in different regions. This offers a multidisciplinary platform for researchers from a broad range of disciplines of Science, Engineering and Technology for reporting innovations at different levels.