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This book describes the latest advances concerning the molecular mechanisms of and therapeutic strategies for alcohol- and non-alcohol-related digestive diseases. Alcohol abuse causes not only liver injury but can harm various organs, resulting in esophageal and colorectal cancers, GERD, pancreatitis, etc. Similar to alcoholic abuse, metabolic syndrome based on obesity and diabetes is also strongly associated with the development of various digestive diseases. Although these diseases may be differentiated by the presence or absence of alcohol intake, the pathologic findings and pathogenesis reveal a number of similarities. This volume covers clinical and basic approaches for esophageal, gastric, hepatic, colorectal and pancreatic diseases associated with alcohol abuse and metabolic syndrome; further, it discusses the roles of microbiota, oxidative stress, and apoptosis, the critical factors causing alcoholic and metabolic digestive diseases. Also, it showcases new pathological and therapeutic perspectives in gastric and pancreatic cancers. Alcoholic/Non-Alcoholic Digestive Diseases will provide invaluable information for doctors specializing in gastroenterology and hepatology and researchers seeking new research on digestive diseases based on alcohol consumption and obesity. ​
Alcohol-related disorders account for an enormous part of the global mortality and morbidity, with most patients being treated in gastroenterology. For this book, a team of internationally renowned experts has contributed state-of-the-art reviews on alcohol-related epidemiology, diseases of the gastrointestinal tract, liver and pancreas as well as the question of how to guide alcoholics psychologically. The first paper evaluates epidemiological data on the impact of alcohol consumption on total morbidity and mortality. This is followed by a critical appraisal of the effect of moderate drinking on the risk and pathophysiological mechanisms of gastrointestinal diseases and of certain health benefits of moderate alcohol consumption. An assessment of available animal models to explain the latest findings in basic alcohol research is followed by a discussion of the effects of alcohol on the various parts of the gastrointestinal system, with special emphasis on the pancreas and liver. Reviews of the well-known association between alcohol consumption and increased risk of cancer and a discussion on how best to care for alcoholics in view of the presented research advances conclude this volume. For those interested in alcohol-related epidemiology, molecular mechanisms, pathophysiology, clinical aspects and the treatment of alcohol-induced diseases of the gastrointestinal tract, liver and pancreas, this publication contains a wealth of information.
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Non-Alcoholic Steatohepatitis: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Non-Alcoholic Steatohepatitis in a compact format. The editors have built Non-Alcoholic Steatohepatitis: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Non-Alcoholic Steatohepatitis in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Non-Alcoholic Steatohepatitis: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Variceal Hemorrhage provides an update of the evidence concerning several aspects of variceal hemorrhage. The book features new information on natural history, diagnosis of esophageal varices, assessment of the risk of bleeding and identification of high risk groups and patients who may benefit or be harmed from different treatments. The volume also presents a critical analysis of the different steps in the management of acute variceal bleeding. Authored by the most prominent world experts in their areas of expertise, Variceal Hemorrhage serves as a very useful reference for gastroenterologists, GI surgeons, residents in internal medicine and physicians dealing with and interested in the different aspects of this severe medical emergency.
Alcoholic Liver Diseases: Advances in Research and Treatment: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Alcoholic Liver Diseases in a compact format. The editors have built Alcoholic Liver Diseases: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Alcoholic Liver Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Alcoholic Liver Diseases: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
The sharp rise in cases of Non-alcoholic fatty liver disease is fast becoming one of the major concerns for hepatologists worldwide. This comprehensive clinical guide explains how to diagnose NAFLD and manage patients according to the best standards of care. Contributors from the world's leading institutions concentrate on patient care, drawing on their extensive experience.
Non-Alcoholic Steatohepatitis: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Non-Alcoholic Steatohepatitis in a compact format. The editors have built Non-Alcoholic Steatohepatitis: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Non-Alcoholic Steatohepatitis in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Non-Alcoholic Steatohepatitis: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Digestive Diseases in Sub-Saharan Africa: Changes and Challenges provides an in-depth examination into the rise of western digestive diseases in Sub-Saharan Africa (SSA). For those interested in the causes of the major diseases of the ‘West’, the patterns in Africa have always reflected on the emergence of western diseases and elucidated the pattern of these conditions and their clinical course. Coverage includes the present epidemiology of GI diseases in SSA, the trends that are occurring, and the context of other emerging diseases. Appropriate for researchers, gastroenterologists and internists, this book brings together the latest research in a single, complete volume. Provides evidence of the changes occurring in digestive disease in Sub-Saharan Africa due to Westernization Covers urbanization, upward mobility, demographics, environmental changes, and the availability of natural resources that have a decisive influence on digestive diseases Offers models for the amelioration of digestive diseases due to Westernization
Cover -- Title -- Copyright -- Contents -- Chapter 1 The Extent of the Problems and the Epidemiological Aspects of Alcohol Drinking -- Chapter 2 The Metabolism of Alcohol and Its Implications for the Pathogenesis of Disease -- Chapter 3 Alcohol and Aldehyde Dehydrogenases in the Gastrointestinal Tract -- Chapter 4 Free Radicals and Ethanol Toxicity -- Chapter 5 Endocrine Changes in Alcoholism with Special Reference to Gastrointestinal Hormones -- Chapter 6 The Physiology of Digestion, Absorption, and Metabolism in the Human Intestine -- Chapter 7 The Effects of Ethanol on Salivary Glands -- Chapter 8 Gastric Cytoprotection and Adaptation to Ethanol -- Chapter 9 Alcoholic Pancreatitis -- Chapter 10 Small Bowel Injury by Ethanol -- Chapter 11 Alcohol-Induced Malabsorption in the Gastrointestinal Tract -- Chapter 12 Alcohol and Small Intestinal Permeability -- Chapter 13 Gastrointestinal Motility Disorders Induced by Ethanol -- Chapter 14 Protein Synthesis in the Gastrointestinal Tract and Its Modification -- Chapter 15 Cell Turnover in the Gastrointestinal Tract and the Effect of Ethanol -- Chapter 16 Lipid Metabolism in the Intestinal Tract and Its Modification by Ethanol -- Chapter 17 Alcohol's Promotion of Gastrointestinal Carcinogenesis -- Chapter 18 Ethanol and the Gastrointestinal Tract: Mechanisms in Disease. Nutritional Implications of Hepatointestinal Disorders -- Chapter 19 Objectives for Future Research in Understanding the Effects of Ethanol on the Gastrointestinal Tract -- Index