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Understanding the many complex cellular and molecular mechanisms underlying human vascular diseases is essential in improving the treatment of this important and wide-ranging group of diseases that affect a large proportion of the world po- lation. This book is based on lectures presented at an International Vascular Biology Workshop held in London and chaired by Professor Dame Carol Black. The c- tents are complemented by some invited chapters, all written by world experts in areas of basic science and clinical medicine highly relevant to vascular biology and disease. We are particularly grateful to Professor Arshed Quyyumi, Professor of Medicine and Cardiology at Emory University, who with his research group and clinical colleagues, has provided a substantial contribution to this book. In common with our previous book – Vascular Complications in Human Disease: Mechanisms and Consequences published by Springer in 2008, our aim with this book is to highlight some of the established relationships between basic science and clinical medicine, and to outline new and exciting fields of research and practice in vascular biology and pathobiology. There are two sections: Basic Science of Vascular Biology and Clinical Aspects of Vascular Biology. In the first section, dealing with basic science, we have included three important growth areas: “Genetics and Gene Therapy” cover approaches to gene therapy and delivery systems, “Animal Models to Study Vascular Disease” with chapters on animal models of scleroderma, animal models of atherosclerosis, and finally on the endothelin system.
With authoritative coverage of everything from recent discoveries in the field of vascular biology to recent clinical trials and evidence-based treatment strategies, Vascular Medicine, 3rd Edition, is your go-to resource for improving your patients’ cardiovascular health. Part of the Braunwald family of renowned cardiology references, this updated volume integrates a contemporary understanding of vascular biology with a thorough review of clinical vascular diseases, making it an ideal reference for vascular medicine specialists, general cardiologists, interventional cardiologists, vascular surgeons, and interventional radiologists. Incorporates technologic advances in vascular imaging – including ultrasound, MRI, CTA, and catheter-based angiography – along with more than 230 new figures, providing an up-to-date and complete view of the vascular system and vascular diseases. Covers novel antithrombotic therapies for peripheral artery disease and venous thromboemboism, advances in endovascular interventions for aortic aneurysms, and today’s best surgical treatments for vascular diseases. Includes seven new chapters: Pathobiology of Aortic Aneurysms; Pathobiology and Assessment of Cardiovascular Fibrosis; Large Vessel Vasculitis; Medium and Small Vessel Vasculitis; Epidemiology and Prognosis of Venous Thromboembolic Disease; Fibromuscular Dysplasia; and Dermatologic Manifestations of Vascular Disease. Discusses methods for aggressive patient management and disease prevention to ensure minimal risk of further cardiovascular problems. Keeps you current with ACC/AHA and ECC guidelines and the best ways to implement them in clinical practice.
Comprehensive Review in Vascular and Endovascular Medicine provides a primer for clinicians care for patients with vascular disease and incorporates the latest information on medical, endovascular, and surgical therapies.
This textbook focuses on the vascular biology and physiology that underlie vascular disorders in clinical medicine. Vascular biomedicine is a rapidly growing field as new molecular mechanisms of vascular health and disease are unraveled. Many of the major cardiovascular diseases including coronary artery disease, heart failure, stroke and vascular dementia are diseases of the vasculature. In addition vascular injury underpins conditions like kidney failure and cardiovascular complications of diabetes. This field is truly multidisciplinary involving scientists in many domains such as molecular and vascular biology, cardiovascular physiology and pharmacology and immunology and inflammation. Clinically, specialists across multiple disciplines are involved in the management of patients with vascular disorders, including cardiologists, nephrologists, endocrinologists, neurologists and vascular surgeons. This book covers a wide range of topics and provides an overview of the discipline of vascular biomedicine without aiming at in-depth reviews, but rather offering up-to-date knowledge organized in concise and structured chapters, with key points and pertinent references. The structure of the content provides an integrative and translational approach from basic science (e.g. stem cells) to clinical medicine (e.g. cardiovascular disease). The content of this book is targeted to those who are new in the field of vascular biology and vascular medicine and is ideal for medical students, graduate and postgraduate students, clinical fellows and academic clinicians with an interest in the vascular biology and physiology of cardiovascular disease and related pathologies.
Translational medicine underpins vascular medicine. It is fundamental to understanding how we treat patients with vascular disease and more importantly, how to prevent it. It is the rationale for drug design and production. Vascular medicine and translational medicine will take over and become the main reason for referring patients to hospital. Therefore, hospital-based clinicians working with basic scientists need to know about translational medicine, which educates and informs them about vascular medicine and how management should be based. This book is a primer for translational vascular medicine and discusses the evolving and exciting areas of basic science applied to vascular medicine. The book is based on the third vascular biology conference held at The Royal College of Physicians in 2008. It provides a large amount of new basic and clinical information and the contributors are world leaders.
Current Therapy in Vascular and Endovascular Surgery is an ideal medical reference book to consult for information in this ever-changing field! Thoroughly revised to reflect the most recent innovations in vascular and endovascular surgery, it features more than 150 chapters on topics new to this edition, and equips residents and practitioners alike with the latest procedures and techniques in this rapidly growing area. Internationally recognized experts present expanded coverage of a wide array of topics, keeping you abreast of all of today's developments! Consult this title on your favorite device, conduct rapid searches, and adjust font sizes for optimal readability. Quickly locate key information with concise, to-the-point chapters. Prepare for boards or certification exams through coverage that spans the entire spectrum of vascular surgery. Explore brand-new coverage of endovascular procedures and techniques. Learn from leaders in the field, including internationally recognized editors and numerous global experts in specialized disciplines. Access in-depth, detailed coverage of various vascular diseases, each sub-divided into discrete topics for a more focused approach. View procedures more clearly than ever before with the help of more than 800 full-color illustrations throughout. Access the full text and videos online at Expert Consult.
This new book on vascular malformations brings together international experts to present advances and discuss controversies in the multidisciplinary management of patients with congenital vascular malformations. Major advances in recent years in medical genetics, and tremendous progress in the fields of imaging and minimally invasive percutaneous interventions have revolutionized both evaluation and management of vascular malformations. The six major parts of this state of the art book ensure that the reader has the most up to date valuable clinical information to ensure the delivery of world class clinical practice. Beautifully illustrated with color line drawings, numerous photographs and informative tables, the advances and controversies of the full spectrum of vascular malformations are presented in 90 definitive chapters. Vascular Malformations brings new information and unparalleled insights to vascular specialists and physicians, trainees and allied health professionals who participate in the care of patients with vascular malformations, either in a private practice setting or at a major institution in an interdisciplinary vascular center.
Machine Learning in Cardiovascular Medicine addresses the ever-expanding applications of artificial intelligence (AI), specifically machine learning (ML), in healthcare and within cardiovascular medicine. The book focuses on emphasizing ML for biomedical applications and provides a comprehensive summary of the past and present of AI, basics of ML, and clinical applications of ML within cardiovascular medicine for predictive analytics and precision medicine. It helps readers understand how ML works along with its limitations and strengths, such that they can could harness its computational power to streamline workflow and improve patient care. It is suitable for both clinicians and engineers; providing a template for clinicians to understand areas of application of machine learning within cardiovascular research; and assist computer scientists and engineers in evaluating current and future impact of machine learning on cardiovascular medicine. Provides an overview of machine learning, both for a clinical and engineering audience Summarize recent advances in both cardiovascular medicine and artificial intelligence Discusses the advantages of using machine learning for outcomes research and image processing Addresses the ever-expanding application of this novel technology and discusses some of the unique challenges associated with such an approach
Now greatly expanded to include all common open surgical and endovascular interventions for both arterial and venous diseases, Clinical Scenarios in Vascular Surgery, 2nd Edition, is ideal both for general surgery residents and surgeons in practice. You’ll explore 124 case scenarios, each presented in an easy-to-digest format, designed to be read in one sitting. After each case, there are two multiple choice questions that allow for a self-assessment of the case material. With nearly twice the number of chapters as the first edition, this updated text reflects the tremendous advancements that have been made in the diagnosis and treatment of vascular disease, including the new terminology, tests, and procedures that every contemporary surgeon needs to know.