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The advent of new neutron facilities and the improvement of existing sources and instruments world wide supply the biological community with many new opportunities in the areas of structural biology and biological physics. The present volume offers a clear description of the various neutron-scattering techniques currently being used to answer biologically relevant questions. Their utility is illustrated through examples by some of the leading researchers in the field of neutron scattering. This volume will be a reference for researchers and a step-by-step guide for young scientists entering the field and the advanced graduate student.
This book provides a comprehensive and up-to-date introduction to the fundamental theory and applications of slow-neutron scattering.
1 Introduction.- 2 Neutron Scattering and Neutron Spin Echo.- 3 Large Scale Dynamics of Homopolymers.-
This 2-volume set includes extensive discussions of scattering techniques (light, neutron and X-ray) and related fluctuation and grating techniques that are at the forefront of this field. Most of the scattering techniques are Fourier space techniques. Recent advances have seen the development of powerful direct imaging methods such as atomic force microscopy and scanning probe microscopy. In addition, techniques that can be used to manipulate soft matter on the nanometer scale are also in rapid development. These include the scanning probe microscopy technique mentioned above as well as optical and magnetic tweezers.
This practical guidebook is written for graduate and post-doctoral students, as well as for experienced researchers new to neutron scattering. Introductory chapters summarize useful scattering formulas and describe the components of a spectrometer. The authors then discuss the resolution function and focusing effects. Simple examples of phonon and magnon measurements are presented. Important chapters cover spurious effects in inelastic and elastic measurements, and how to avoid them. The last chapter covers techniques for, and applications of, polarization analysis.
Neutron Scattering from Magnetic Materials is a comprehensive account of the present state of the art in the use of the neutron scattering for the study of magnetic materials. The chapters have been written by well-known researchers who are at the forefront of this field and have contributed directly to the development of the techniques described. Neutron scattering probes magnetic phenomena directly. The generalized magnetic susceptibility, which can be expressed as a function of wave vector and energy, contains all the information there is to know about the statics and dynamics of a magnetic system and this quantity is directly related to the neutron scattering cross section. Polarized neutron scattering techniques raise the sophistication of measurements to even greater levels and gives additional information in many cases. The present book is largely devoted to the application of polarized neutron scattering to the study of magnetic materials. It will be of particular interest to graduate students and researchers who plan to investigate magnetic materials using neutron scattering.· Written by a group of scientist who have contributed directly in developing the techniques described.· A complete treatment of the polarized neutron scattering not available in literature.· Gives practical hits to solve magnetic structure and determine exchange interactions in magnetic solids.· Application of neutron scattering to the study of the novel electronic materials.
Inelastic neutron scattering (INS) is a spectroscopic technique in which neutrons are used to probe the dynamics of atoms and molecules in solids and liquids. This book is the first, since the late 1960s, to cover the principles and applications of INS as a vibrational-spectroscopic technique. It provides a hands-on account of the use of INS, concentrating on how neutron vibrational spectroscopy can be employed to obtain chemical information on a range of materials that are of interest to chemists, biologists, materials scientists, surface scientists and catalyst researchers. This is an accessible and comprehensive single-volume primary text and reference source.
Neutron optics studies the interactions of a beam of slow neutrons with matter. This book updates various advances on neutron optics. There will be a focus on the very active topics of neutron imaging (NI) and neutron spin optics (NSO). The book will also present applications of neutron beams in biomedicine, such as Boron Neutron Capture Therapy (BNCT) and related techniques. Features: Discusses diffraction and interference of slow neutrons, including computational approaches Reviews neutron imaging (NI) and neutron spin optics (NSO) Treats two major sources of slow neutron beams: (1) fission reactions at nuclear reactors and (2) collisions in particle accelerators (small ones, spallation sources) of charged particle beams with targets of heavy atoms Selects subjects on fundamental quantum aspects of slow neutrons and on confined propagation and waveguiding thereof Updates slow neutron beams and BNCT
Neutron Imaging and Applications offers an introduction to the basics of neutron beam production in addition to the wide scope of techniques that enhance imaging application capabilities. An instructional overview of neutron sources, detectors, optics and spin-filters allows readers to delve more deeply into the discussions of radiography, tomography and prospective applications available in neutron holography techniques. A section devoted to current applications describes imaging single grains in polycrystalline materials, neutron imaging of geological materials and other materials science and engineering areas. Coverage of thermal neutron imaging of biological tissues, plant physiology, Homeland Security and contraband detection explore the future prospects of this cutting-edge research. Written by key experts in the field, researchers and engineers involved with imaging technologies will find Neutron Imaging and Applications a valuable reference.
Biological membranes are the essential structuring elements of all living cells. Many enzymatic reactions take place at the membrane-water interface. To gain detailed insight into membrane properties, it is therefore of great importance to understand the complex nature of the interactions of membrane proteins with lipids. Lipid-Protein Interactions: Methods and Protocols provides a selection of protocols to examine protein-lipid interactions, membrane and membrane protein structure, how membrane proteins affect lipids and how they are in turn affected by the lipid bilayer and lipid properties. The methods described here are all actively used, complementary, and necessary to obtain comprehensive information about membrane structure and function. They include label-free approaches, imaging techniques and spectroscopic methodologies. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Lipid-Protein Interactions: Methods and Protocols seeks to serve both professional and novices with its wide range of the methods frequently used in this area of research.