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The present book is covers the recent advances in the development on the regulation of such theragnosis system and their biomedical perspectives to act as a future nanomedicine. Advanced Theranostics Materialsis written by a distinguished group of contributors and provides comprehensive coverage of the current literature, up-to-date overview of all aspects of advanced theranostics materials ranging from system biology, diagnostics, imaging, image-guided therapy, therapeutics, biosensors, and translational medicine and personalized medicine, as well as the much broader task of covering most topics of biomedical research. The books focusses on the following topics: Part 1: System biology and translational medicine Aberrant Signaling Pathways: Hallmark of Cancer Cells and Target for Nanotherapeutics Application of Nanoparticles in Cancer Treatment Biomacromolecule-Gated Mesoporous Silica Drug Delivery Systems Construction of Functional DNA Nanostructures for Theranostic Applications Smart Polypeptide Nanocarriers for Malignancy Therapeutics Part 2: Imaging and therapeutics Dimercaptosuccinic acid-coated magnetic nanoparticles as a localized delivery system in cancer immunotherapy Cardiovascular nanomedicine Chitosan-based systems for sustained drug release Nanocapsules in biomedicine: promises and challenges Chitosan-based polyelectrolyte complexes: characteristics and application in formulation of particulate drug carriers Part 3: Diagnostics and featured prognostics Non-invasive Glucose Biosensors based on Nanomaterials Self/directed Assembly of Nanoparticles: A review on various approaches Ion exchangers – an open window for the development of advanced materials with pharmaceutical and medical applications New Titanium Alloys for Biomedical Applications
Advanced Nanoformulations: Theranostic Nanosystems, Volume Three examines the applications of nanotherapeutic systems and nanodiagnostics in relation to polymeric nanosystems. In the last decade, numerous biopolymers have been utilized to prepare polymeric nanosystems for therapeutic applications. These biopolymers include polylactic acid, polylactide-co-glycolide, polycaprolactone, acrylic polymers, cellulose and cellulose derivatives, alginates, chitosan, gellan gum, gelatin, albumin, chontroitin sulfate, hyaluronic acid, guar gum, gum Arabic, gum tragacanth, xanthan gum, and starches. Besides these biopolymers, grafted polymers are also being used as advanced polymeric materials to prepare many theranostic nanocarriers and nanoformulations. This book explores the array of polymeric nanosystems to understand therapeutic potentials. It will be useful to pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals, and regulatory scientists actively involved in the pharmaceutical product and process development of tailor-made polysaccharides in drug delivery applications. - Contains in-depth discussions of the advanced formulations using nanosystems including high-quality graphics, flowcharts, and graphs for enhanced understanding - Reviews the literature on advanced formulations while also suggesting new avenues - Includes contributions in all areas of advanced formulations, providing a thorough and interdisciplinary work
Handbook of Nanomaterials for Cancer Theranostics focuses on recent developments in advanced theranostic nanomedicines from a chemical and biological perspective where the advantages of theranostics are achieved by combining multiple components. The authors explore the pros and cons of theranostic nanomaterials developed in cancer research in the last 15 years, with the different strategies compared and scrutinized. In addition, the book explores how nanomaterials may overcome the regulatory hurdles facing theranostic nanomedicines. This is an important research reference for postgraduates and researchers in nanomedicine and cancer research who want to learn more on how nanomaterials can help create more effective cancer treatments. - Highlights the development of smart theranostic nanomaterials to tackle biomedical problems in cancer therapy and diagnostics - Explores the regulatory hurdles facing theranostic nanomedicine - Discusses how the use of nanomaterials can help create more effective cancer treatments
A comprehensive discussion of various types of nanoengineered biomaterials and their applications In Nanoengineering of Biomaterials: Drug Delivery & Biomedical Applications, an expert team of chemists delivers a succinct exploration of the synthesis, characterization, in-vitro and in-vivo drug molecule release, pharmacokinetic activity, pharmacodynamic activity, and the biomedical applications of several types of nanoengineered biomaterials. The editors have also included resources to highlight the most current developments in the field. The book is a collection of valuable and accessible reference sources for researchers in materials chemistry and related disciplines. It uses a functions-directed approach to using organic and inorganic source compounds that translate into biological systems as scaffolds, micelles, dendrimers, and other delivery systems. Nanoengineering of Biomaterials offers readers up-to-date chemistry and material science insights that are readily transferrable to biomedical systems. The book also includes: Thorough introductions to alginate nanoparticle delivery of therapeutics and chitosan-based nanomaterials in biological applications Comprehensive explorations of nanostructured carrageenan as a drug carrier, gellan gum nanoparticles in drug delivery, and guar-gum nanoparticles in the delivery of bioactive molecules Practical discussions of protein-based nanoparticles for drug delivery, solid lipid nanoparticles as drug carriers, and pH-responsive nanoparticles in therapy In-depth examinations of stimuli-responsive nano carriers in drug targeting Perfect for pharmaceutical chemists, materials scientists, polymer chemists, life scientists, and medicinal chemists, Nanoengineering of Biomaterials: Drug Delivery and Biomedical Applications is also an indispensable resource for biologists and bioengineers seeking a one-stop reference on the transferability of materials chemistry and nanotechnology to biomedicine.
Multifunctional Theranostic Nanomedicines in Cancer focuses on new trends, applications, and the significance of novel multifunctional nanotheranostics in cancer imaging for diagnosis and treatment. Cancer nanotechnology offers new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions—including targeting, imaging, and therapy—have been intensively studied with the goal of overcoming the limitations of conventional cancer diagnosis and therapy. Thus theranostic nanomedicines have emerged in recent years to provide an efficient and safer alternative in cancer management. This book covers polymer-based therapies, lipid-based therapies, inorganic particle-based therapies, photo-related therapies, radiotherapies, chemotherapies, and surgeries. Multifunctional Theranostic Nanomedicines in Cancer offers an indispensable guide for researchers in academia, industry, and clinical settings; it is also ideal for postgraduate students; and formulation scientists working on cancer. - Provides a comprehensive resource of recent scientific progress and novel applications of theranostic nanomedicines - Discusses treatment options from a pharmaceutical sciences perspective - Includes translational science and targeted CNS cancer treatment
This book provides up-to-date information on the prototypes used to develop medical devices and explains the principles of biosensing and theranostics. It also discusses the development of biosensor and application-orientated design of medical devices. In addition to summarizing the clinical validation of the developed techniques and devices and the regulatory steps involved in their commercialization, the book highlights the latest research and translational technologies toward the development of point-of-care devices in the health care. Lastly, it explores the current opportunities, challenges and provides troubleshooting on the use of biosensors in precision medicine. The book is helpful for researchers and medical professionals working in the field of clinical theranostics, and medical-device development wanting to gain a better understanding into the principles and processes involved in the development of biosensors.
Aiding researchers seeking to eliminate multi-step procedures, reduce delays in treatment and ease patient care, Cancer Theranostics reviews, assesses, and makes pertinent clinical recommendations on the integration of comprehensive in vitro diagnostics, in vivo molecular imaging, and individualized treatments towards the personalization of cancer treatment. Cancer Theranostics describes the identification of novel biomarkers to advance molecular diagnostics of cancer. The book encompasses new molecular imaging probes and techniques for early detection of cancer, and describes molecular imaging-guided cancer therapy. Discussion also includes nanoplatforms incorporating both cancer imaging and therapeutic components, as well as clinical translation and future perspectives. - Supports elimination of multi-step approaches and reduces delays in treatments through combinatorial diagnosis and therapy - Fully assesses cancer theranostics across the emergent field, with discussion of biomarkers, molecular imaging, imaging guided therapy, nanotechnology, and personalized medicine - Content bridges laboratory, clinic, and biotechnology industries to advance biomedical science and improve patient management
Functionalized Carbon Nanomaterials for Theranostic Applications offers insights into the developments and trends that are progressing fast in the field of functionalized carbon nanomaterials-based devices as diagnostic tools for early stage detection of human diseases. The book provides information on how functionalized carbon nanomaterials are being used as the basis for products, such as early disease diagnostic kits, quantum dots for medical imaging and a growing list of other applications. Sections cover different mechanical, absorption, optical and electrical properties than those found in original nanomaterials. This is an important reference source that will be valuable to materials scientists, biomedical engineers and pharmaceutical scientists who are looking to increase their understanding on how functionalized carbon nanomaterials are being used for a variety of theranostic applications. - Provides readers with information on how to develop functionalized carbon nanomaterials based diagnostic devices and tools - Identifies fabrication and characterization methods for integrated devices for use in theranostic applications - Assesses major challenges for manufacturing functionalized carbon nanomaterial materials for theranostic devices on an industrial scale
This volume presents papers on the topics covered at the National Academy of Engineering's 2018 US Frontiers of Engineering Symposium. Every year the symposium brings together 100 outstanding young leaders in engineering to share their cutting-edge research and innovations in selected areas. The 2018 symposium was held September 5-7 and hosted by MIT Lincoln Laboratory in Lexington, Massachusetts. The intent of this book is to convey the excitement of this unique meeting and to highlight innovative developments in engineering research and technical work.