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Magnetic Resonance Imaging (MRI) scans play a vital role in diagnosis and monitoring of diseases across the body. However, MRI is a relatively slow imaging technology, resulting in long scan times. This is particularly challenging when imaging dynamic processes. Accelerated Dynamic Magnetic Resonance Imaging: Methods and Applications explains the technologies which can speed up MRI imaging and shows how they have been applied to a broad range of application areas, presenting the challenges and giving practical advice on implementation. With this book the reader will be able to: Modify the MRI sequences to speed up acquisition of data (non-Cartesian trajectories and data under sampling); Use the techniques (parallel imaging, compressed sensing and machine learning) which are commonly used to reconstruct under sampled MRI data; Implement fast MRI imaging techniques for their application areas. Accelerated Dynamic Magnetic Resonance Imaging: Methods and Applications is an ideal resource for the technologist, clinical researcher and clinician who want to understand rapid MRI methods and gain practical advice on their implementation.
Magnetic Resonance Image Reconstruction: Theory, Methods and Applications presents the fundamental concepts of MR image reconstruction, including its formulation as an inverse problem, as well as the most common models and optimization methods for reconstructing MR images. The book discusses approaches for specific applications such as non-Cartesian imaging, under sampled reconstruction, motion correction, dynamic imaging and quantitative MRI. This unique resource is suitable for physicists, engineers, technologists and clinicians with an interest in medical image reconstruction and MRI. - Explains the underlying principles of MRI reconstruction, along with the latest research - Gives example codes for some of the methods presented - Includes updates on the latest developments, including compressed sensing, tensor-based reconstruction and machine learning based reconstruction
Magnetic resonance imaging (MRI) is a powerful diagnostic tool for visualizing soft tissue anatomy, but physical limits on data acquisition speed result in uncomfortably long MRI exams. This is problematic for many patient populations, but especially for pediatric patients, who often require general anesthesia (GA) to reduce anxiety and body motion. Many attempts at accelerating data acquisition have been made to reduce or eliminate use of GA for pediatric MRI. For example, compressed sensing (CS) methods have been used to iteratively reconstruct rapidly acquired measurements into high-quality images by leveraging sparse priors. More recently, deep learning (DL) methods have been used to train deep neural network models to map the rapidly acquired measurements into even higher-quality images. While DL reconstruction approaches may potentially accelerate data acquisition beyond CS, these approaches have several issues which impede their clinical adoption. First, DL reconstructions require large quantities of high-quality ground truth data for supervised training, which can be costly and time-consuming to acquire. Second, memory requirements during network training limit the applicability of DL reconstruction to low-dimensional MRI data, such as static or dynamic 2-D imaging with limited spatiotemporal resolution. In this thesis, a series of projects demonstrating robust DL reconstruction techniques for acceleration of high-dimensional pediatric MRI will be presented. First, physics-based models are incorporated into deep CNN architectures to enforce consistency between intermediate network outputs and the rapidly acquired measurements in a novel method called DL-ESPIRiT. Physics-based modeling allows DL-ESPIRiT to be trained end-to-end in a supervised fashion with relatively little training data compared to non-physics-driven DL reconstruction. DL-ESPIRiT is applied and validated on 12X prospectively accelerated dynamic 2-D MRI scans acquired at Lucile Packard Children's Hospital. Finally, DL-ESPIRiT is extended to leverage subspace methods within the network to address GPU memory limitations during training. This method, known as deep learning-based subspace reconstruction (DL-Subspace), reconstructs a compressed representation of the MRI data instead of the data directly, thereby reducing the memory footprint during training and accelerating DL inference times. DL-Subspace is demonstrated to reconstruct 2-D dynamic MRI data with 4X higher memory efficiency and inference speed.
HANDBOOK OF INTELLIGENT COMPUTING AND OPTIMIZATION FOR SUSTAINABLE DEVELOPMENT This book provides a comprehensive overview of the latest breakthroughs and recent progress in sustainable intelligent computing technologies, applications, and optimization techniques across various industries. Optimization has received enormous attention along with the rapidly increasing use of communication technology and the development of user-friendly software and artificial intelligence. In almost all human activities, there is a desire to deliver the highest possible results with the least amount of effort. Moreover, optimization is a very well-known area with a vast number of applications, from route finding problems to medical treatment, construction, finance, accounting, engineering, and maintenance schedules in plants. As far as optimization of real-world problems is concerned, understanding the nature of the problem and grouping it in a proper class may help the designer employ proper techniques which can solve the problem efficiently. Many intelligent optimization techniques can find optimal solutions without the use of objective function and are less prone to local conditions. The 41 chapters comprising the Handbook of Intelligent Computing and Optimization for Sustainable Development by subject specialists, represent diverse disciplines such as mathematics and computer science, electrical and electronics engineering, neuroscience and cognitive sciences, medicine, and social sciences, and provide the reader with an integrated understanding of the importance that intelligent computing has in the sustainable development of current societies. It discusses the emerging research exploring the theoretical and practical aspects of successfully implementing new and innovative intelligent techniques in a variety of sectors, including IoT, manufacturing, optimization, and healthcare. Audience It is a pivotal reference source for IT specialists, industry professionals, managers, executives, researchers, scientists, and engineers seeking current research in emerging perspectives in the field of artificial intelligence in the areas of Internet of Things, renewable energy, optimization, and smart cities.
The field of magnetic resonance imaging (MRI) has developed rapidly over the past decade, benefiting greatly from the newly developed framework of compressed sensing and its ability to drastically reduce MRI scan times. MRI: Physics, Image Reconstruction, and Analysis presents the latest research in MRI technology, emphasizing compressed sensing-based image reconstruction techniques. The book begins with a succinct introduction to the principles of MRI and then: Discusses the technology and applications of T1rho MRI Details the recovery of highly sampled functional MRIs Explains sparsity-based techniques for quantitative MRIs Describes multi-coil parallel MRI reconstruction techniques Examines off-line techniques in dynamic MRI reconstruction Explores advances in brain connectivity analysis using diffusion and functional MRIs Featuring chapters authored by field experts, MRI: Physics, Image Reconstruction, and Analysis delivers an authoritative and cutting-edge treatment of MRI reconstruction techniques. The book provides engineers, physicists, and graduate students with a comprehensive look at the state of the art of MRI.
Quantitative Magnetic Resonance Imaging is a 'go-to' reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: - The basic physics behind tissue property mapping - How to implement basic pulse sequences for the quantitative measurement of tissue properties - The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* - The pros and cons for different approaches to mapping perfusion - The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor - maps and more complex representations of diffusion - How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed - How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance - Fingerprinting can be used to accelerate or improve tissue property mapping schemes - How tissue property mapping is used clinically in different organs - Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds - Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements - Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges - Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches
Dynamic contrast-enhanced MRI is now established as the methodology of choice for the assessment of tumor microcirculation in vivo. The method assists clinical practitioners in the management of patients with solid tumors and is finding prominence in the assessment of tumor treatments, including anti-angiogenics, chemotherapy, and radiotherapy. Here, leading authorities discuss the principles of the methods, their practical implementation, and their application to specific tumor types. The text is an invaluable single-volume reference that covers all the latest developments in contrast-enhanced oncological MRI.
Expecting the reader to have some basic training in liner algebra and optimization, the book begins with a general discussion on CS techniques and algorithms. It moves on to discussing single channel static MRI, the most common modality in clinical studies. It then takes up multi-channel MRI and the interesting challenges consequently thrown up in signal reconstruction. Off-line and on-line techniques in dynamic MRI reconstruction are visited. Towards the end the book broadens the subject by discussing how CS is being applied to other areas of biomedical signal processing like X-ray, CT and EEG acquisition. The emphasis throughout is on qualitative understanding of the subject rather than on quantitative aspects of mathematical forms. The book is intended for MRI engineers interested in the brass tacks of image formation; medical physicists interested in advanced techniques in image reconstruction; and mathematicians or signal processing engineers.