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Clear guidelines on the proper care and use of laboratory animals are being sought by researchers and members of the many committees formed to oversee animal care at universities as well as the general public. This book provides a comprehensive overview of what we know about behavior, pain, and distress in laboratory animals. The volume explores: Stressors in the laboratory and the animal behaviors they cause, including in-depth discussions of the physiology of pain and distress and the animal's ecological relationship to the laboratory as an environment. A review of euthanasia of lab animals-exploring the decision, the methods, and the emotional effects on technicians. Also included is a highly practical, extensive listing, by species, of dosages and side effects of anesthetics, analgesics, and tranquilizers.
Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic, and postoperative care requirements associated with experimental surgery. Fully revised and updated this new edition provides the reader with agents, methods, and techniques for anesthesia and analgesia that ensure humane and successful procedural outcomes. - Provides researchers with the most comprehensive and up-to-date review of the use of anesthesia and analgesia in laboratory animals - Thoroughly updated with new material on ferrets, birds, reptiles, amphibians, fish, and invertebrates - Includes hot topic areas such as pain research, ethical issues, legal issues, and imaging studies
Essentials of Small Animal Anesthesia and Analgesia, Second Edition presents the fundamentals of managing small animal anesthesia patients in a clinically relevant, accessible manual. The bulk of the book is distilled from Lumb and Jones' Veterinary Anesthesia and Analgesia to provide authoritative information in a quick-reference format, with references to Lumb and Jones' throughout for easy access to further detail. Logically reorganized with an easy-to-use structure and an increased focus on pain management, this new edition features new chapters on equipment and managing specific conditions. The Second Edition has been updated to reflect current practices in anesthesia and analgesia, and a new companion website offers review questions and answers, video clips, and an image bank with additional figures not found in the printed book. Essentials of Small Animal Anesthesia and Analgesia, Second Edition provides veterinary care providers and students with key information on anesthetic and analgesic pharmacology, physiology, patient assessment, and clinical case management.
Veterinary Anesthesia and Analgesia: the Fifth Edition of Lumb and Jones is a reorganized and updated edition of the gold-standard reference for anesthesia and pain management in veterinary patients. Provides a thoroughly updated edition of this comprehensive reference on veterinary anesthesia and analgesia, combining state-of-the-art scientific knowledge and clinically relevant information Covers immobilization, sedation, anesthesia, and analgesia of companion, wild, zoo, and laboratory animals Takes a body systems approach for easier reference to information about anesthetizing patients with existing conditions Adds 10 completely new chapters with in-depth discussions of perioperative heat balance, coagulation disorders, pacemaker implantation, cardiac output measurement, cardiopulmonary bypass, shelter anesthesia and pain management, anesthetic risk assessment, principles of anesthetic pharmacology, and more Now printed in color, with more than 400 images
In this first in a proposed series of workshops on regulatory issues in animal care and use, the Institute for Laboratory Animal Research (ILAR) has addressed the existing and proposed requirements for reporting pain and distress in laboratory animals. The Animal Welfare Act, administered by the Animal and Plant Health Inspection Service of the United States Department of Agriculture (USDA), mandates that pain and distress in laboratory animals be minimized. USDA is considering two policy changes with regard to this specific mandate. Firstly, since there has been no functional definition of "distress," USDA has prepared such a definition and requested feedback from the scientific community on its usefulness for regulatory and reporting requirements. The second issue concerns the pain and distress categorization scheme for reporting to USDA. Various groups and individuals have questioned the efficacy of the current categories, and specific changes have been proposed by the Humane Society of the United States. USDA is considering these and other potential changes to the existing scheme. Thus, given these potential changes to animal welfare policy, the aim of the ILAR/NIH joint workshop was to provide feedback to the USDA. The speakers were asked to address these two issues as well as to comment upon whether the information contained in the 1992 ILAR report Recognition and Alleviation of Pain and Distress in Laboratory Animals is still useful to investigators in assisting them to comply with regulations. The speakers provided perspectives based on their individual expertise in the areas of science of pain and distress, animal welfare policy, protocol review, and/or as representatives of relevant organizations or institutions. The following proceedings are an edited transcript of their presentations.
Small Animal Regional Anesthesia and Analgesia is an up-to-date, complete resource for performing local anesthetic techniques in small animals. This practical, clinically oriented reference presents step-by-step procedures for performing common locoregional blocks and is organized logically by body system. The first book to draw information on this topic into one resource, Small Animal Regional Anesthesia and Analgesia is equally useful as a comprehensive reference and as a quick source of information with checklists and pictures to assist with performing various blocks in practice. Beginning with introductory sections offering an overview of general considerations for patient preparation and pharmacology, the heart of the book is devoted to detailed instructions for performing regional anesthetic techniques, including reviews of the literature, useful illustrations, diagrams, and clinical tips. Small Animal Regional Anesthesia and Analgesia provides an invaluable tool for veterinary anesthesiologists and practitioners who incorporate local and regional anesthetic techniques into their small animal practices.
The use of animals in research adheres to scientific and ethical principles that promote humane care and practice. Scientific advances in our understanding of animal physiology and behavior often require theories to be revised and standards of practice to be updated to improve laboratory animal welfare. Recognition and Alleviation of Pain in Laboratory Animals, the second of two reports revising the 1992 publication Recognition and Alleviation of Pain and Distress in Laboratory Animals from the Institute for Laboratory Animal Research (ILAR), focuses on pain experienced by animals used in research. This book aims to educate laboratory animal veterinarians; students, researchers and investigators; Institutional Animal Care and Use Committee members; and animal care staff and animal welfare officers on the current scientific and ethical issues associated with pain in laboratory animals. It evaluates pertinent scientific literature to generate practical and pragmatic guidelines for recognizing and alleviating pain in laboratory animals, focusing specifically on the following areas: physiology of pain in commonly used laboratory species; pharmacologic and non-pharmacologic principles to control pain; identification of humane endpoints; and principles for minimizing pain associated with experimental procedures. Finally, the report identifies areas in which further scientific investigation is needed to improve laboratory animal welfare.
Pain Management in Veterinary Practice provides veterinary practitioners with the information needed to recognize and manage pain in a wide range of large, small, and exotic animal species. Encompassing acute, adaptive, and chronic, maladaptive pain, the book provides an up-to-date review of the physiology and pathophysiology of pain. Pain Management in Veterinary Practice offers specific strategies for addressing pain in animals, including local and regional analgesia, continuous rate infusions, and novel methods of analgesic drug delivery. With comprehensive information on the pharmacokinetic and pharmacodynamic characteristics of analgesic drugs, the book goes beyond pharmaceutical options to incorporate scientific information on techniques for complementary treatment, including physical therapy, acupuncture, chiropractic techniques, and nutritional strategies. Pain Management in Veterinary Practice is a valuable resource for developing pain management protocols in the veterinary clinic.
A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.