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​​This is the first major textbook to address both computed tomography (CT) and magnetic resonance (MR) cardiac imaging of adults for the diagnosis and treatment of congenital heart disease (CHD). Since the introduction of faster CT scanners, there has been tremendous advancement in the diagnosis of CHD in adults. This is mostly due to the higher spatial resolution of CT compared to MR, which enables radiologists to create more detailed visualizations of cardiac anatomic structures, leading to the discovery of anomalous pathologies often missed by conventional MR imaging. This book is unique in highlighting the advantages of both CT and MR for the diagnosis of CHD in adults, focusing on the complementary collaboration between the two modalities that is possible. Chapters include discussions of case examples, clinical data, MR and CT image findings, and correlative cadaveric pictures. The chapters focus not only on the diagnosis of the primary problem, but also give readers information on visual clues to look for that often reveal associated pathologies. This book appeals primarily to diagnostic and interventional radiologists, as well as cardiologists and interventional cardiologists.
A Wall Street Journal Business Book Bestseller "Primitive provides a path forward to unleash your inner entrepreneur."―Barbara Corcoran, Shark Tank Most people are disengaged with their work and feel uninspired, underappreciated and underpaid. The situation could hardly be clearer: in the wake of a catastrophic global health crisis and amid societal upheaval and economic uncertainty, we can longer afford to play by the conventional rulebook to get ahead in our professional lives. What’s the secret to this kind of success in today’s world? Ironically, it’s honoring our ancient instincts and intuition. It’s about sensing danger and pouncing on opportunity -- as our ancestors did tens of thousands of years ago, or in the manner of playful kids full of curiosity and can-do spirit. Primitive is very different from the familiar, cookie-cutter business book. Marco Greenberg, a close advisor to visionary founders of tech unicorns and the heads of some of the nation’s largest organizations, demonstrates how a range of successful people--those he calls "primitives"--ignore what they "should" do and instead tap a primal drive to power ahead. The good news is that anyone looking to inspire others has a way to apply the primitive mindset, from new college grads to mid-career professionals, from HR directors to CEOs. The key is to go ROAMING ™: be Relentless in pursuing our biggest goals; have the courage to reject group-think and be Oppositional; choose an Agnostic approach rather than overly specialize; adopt a Messianic spirit, so your work becomes not just a job but a true calling; embrace the advantages of being Insecure rather than feign bravado; reap the benefits of sometimes acting a little Nuts; and finally, to realize that being Gallant in following one's passions delivers the ultimate rewards. Primitive captures the keys to breakout success and professional satisfaction.
This classic work in the anthropology of law offers ambitiously conceived analyses of the fundamental rights and duties treated as law among nonliterate peoples. The heart of the book is an analysis of the law of five societies: the Eskimo; the Ifugao; the Comanche, Kiowa, and Cheyenne tribes; the Trobriand Islanders; and the Ashanti.
The overall scope of this new series will be to evolve an understanding of the genetic basis of (1) how early mesoderm commits to cells of a heart lineage that progres sively and irreversibly assemble into a segmented, primary heart tube that can be remodeled into a four-chambered organ, and (2) how blood vessels are derived and assembled both in the heart and in the body. Our central aim is to establish a four-dimensional, spatiotemporal foundation for the heart and blood vessels that can be genetically dissected for function and mechanism. Since Robert DeHaan's seminal chapter "Morphogenesis of the Vertebrate Heart" published in Organogenesis (Holt Rinehart & Winston, NY) in 1965, there have been surprisingly few books devoted to the subject of cardiovascular morpho genesis, despite the enormous growth of interest that occurred nationally and internationally. Most writings on the subject have been scholarly compilations of the proceedings of major national or international symposia or muItiauthored volumes, often without a specific theme. What is missing are the unifying concepts that can make sense out of a burgeoning database of facts. The Editorial Board of this new series believes the time has come for a book series dedicated to cardiovas cular morphogenesis that will serve not only as an important archival and didactic reference source for those who have recently come into the field but also as a guide to the evolution of a field that is clearly coming of age.
The pacemaking and conduction system (PCS) is vital for generating and synchronizing the heart beat. Dysfunction of this system can be a direct cause of cardiac conduction disturbance, arrhythmias and sudden cardiac death. A wealth of information has been collected over many years on the unique histological, morphological and phenotypic characteristics of specialized cardiac tissues. The cellular and molecular mechanisms that govern development of the PCS are now starting to be understood. This book draws together contributions from an international and interdisciplinary group of experts working on both basic and clinical aspects of cardiac development. It features reviews of the structure and function of the developing PCS, discussion of the molecular and cellular mechanisms regulating embryological development of this system and studies on the fundamental basis of PCS pathology. The book also considers how novel therapeutic interventions based on understanding of the developmental biology of cardiac pacemaking and conduction tissues might ultimately impact on clinical medicine.
The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook – inspired by the postgraduate degree program at the University of Oxford – guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.