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Humans and flies look nothing alike, yet their genetic circuits are remarkably similar. Here, Lewis I. Held, Jr compares the genetics and development of the two to review the evidence for deep homology, the biggest discovery from the emerging field of evolutionary developmental biology. Remnants of the operating system of our hypothetical common ancestor 600 million years ago are compared in chapters arranged by region of the body, from the nervous system, limbs and heart, to vision, hearing and smell. Concept maps provide a clear understanding of the complex subjects addressed, while encyclopaedic tables offer comprehensive inventories of genetic information. Written in an engaging style with a reference section listing thousands of relevant publications, this is a vital resource for scientific researchers, and graduate and undergraduate students.
“An immersive fever dream of a novel, beautifully written and boldly imagined.” —Leslie Jamison, New York Times bestselling author of The Empathy Exams From prizewinning writer Joe Fassler comes a brilliant modern reimagining of the myth of Daedalus and Icarus as a story of obsession, longing, and the radical pursuit of utopia It’s 2005, and 24-year-old Jane is miserable. Overworked, buried in debt, she senses the life she wanted slipping away—while the world around her veers badly off course, hurtling toward economic and ecological collapse. She wants to find something better. But she has no idea where to start. In a sudden and unprecedented burst of rebellion, Jane decides to abandon everything she knows, leaving behind her relationships and responsibilities to go on the road. That’s how she meets Barry, a brilliant and charismatic recluse living on an isolated homestead near New York’s Canadian border. For years, in secret, Barry’s chased an unlikely obsession: to build a pair of wings humans can fly in, with designs inspired by an obscure precursor to the Wright Brothers. It’s no mere hobby. He’s convinced his dream of flight will spark a revolution, delivering us from the degradation of modern capitalism and the climate chaos that awaits us. Jane is captivated by Barry’s radical vision, even as his experiments become more dangerous. But she’s equally drawn to the enigmatic Ike, Barry’s gentle, thoughtful son, who’s known no other reality—and who only wants to keep his father alive, tethered to ground and to reason. So begins an inventive, dazzlingly beautiful story about the human desire for transcendence—our longing to escape the mundane and glide into a euphoric future. Inspired by the myth of Daedalus and Icarus, The Sky Was Ours is a powerful and imaginative debut that explores the question: If you had access to technology that allowed you to escape the confines of your life, would you use it? And if Barry’s wings really could change the world, would that be freedom?
How did flying birds evolve from running dinosaurs, terrestrial trotting tetrapods from swimming fish, and whales return to swim in the sea? These are some of the great transformations in the history of life; events that have captured the imagination of scientists and the general public alike. At first glance, these major evolutionary events seem utterly impossible. The before and after look so fundamentally different that the great transformations of the history of life not only seem impossible, but unknowable. The 500 million year history of vertebrates is filled with change and, as a consequence, every living species contains within its structure, DNA, and fossil record, a narrative of them. A battery of new techniques and approaches, from diverse fields of inquiry, are now being marshaled to explore classic questions of evolution. These approaches span multiple levels of biological organization, from DNA sequences, to organs, to the physiology and ecology of whole organisms. Analysis of developmental systems reveals deep homologies of the mechanisms that pattern organs as different as bird wings and fish fins. Whales with legs are one of a number of creatures that tell us of the great transformations in the history of life. Expeditions have discovered worms with a kind of head, fishes with elbows, wrists, and necks; feathered dinosaurs, and human precursors to name only a few. Indeed, in the last 20 years, paleontologists have discovered more creatures informative of evolutionary transitions than in the previous millennium. "The Great Transformations "captures the excitement of these new discoveries by bringing diverse teams of renowned scientists together to attack particular transformations, and to do so in a contents organized by body part--head, neck, fins, limbs, and then the entire bauplan. It is a work that will transform evolutionary biology and paleontology."
Vasopressin and its homologues are evolutionarily ancient neuropeptides that are important to the neural modulation of behavior in many species. Over the last several decades there has been an emergence of cross-species consensus with regards to the broad behavioral domains that the vasopressin system influences. However, there are nuanced species- and sex-differences in the functions of this system, as well as evidence for cross-talk between this system and the oxytocin system. For this Research Topic, reviews and research articles from investigators across the field were solicited, with the goal to highlight some of the complexity and diversity within this system. This collection challenges researchers to broaden their understanding of this system as well as identifies areas in which additional research is needed. Topic areas featured include: - System complexity - Sex and species differences - Developmental effects - Human and non-human primates
Everything you were taught about evolution is wrong.
This new 3-volume set provides informative reviews on the physiology of sponges, cnidarians, round and flat worms, annelids, echinoderms, and crustaceans, advancing our knowledge of the physiology of these major invertebrate groups (Phyla). Invertebrates exhibit the largest number of species and occupy virtually every conceivable ecological niche. They are economically important in food chains, they recycle organic waste, and they are crucial pollinators of plants and sources of food. They are also medically relevant as parasites that cause major diseases in both humans and livestock. Volume 1 looks at non-Bilaterians (sponges, cnidarians, placozoans). The focus on sponge biology has recently been on symbiosis, nutrient uptake, and sensory biology. The section on cnidarians covers biomineralization, the nervous system, and development. The biology of placozoans is described in depth, including the role of neuropeptides in feeding. Volume 2 and covers crustacean physiology and diverse physiological topics, ranging from molting, respiration, water balance, biomineralization, bioreceptors, and temperature regulation to the land adaptation of terrestrial crustaceans. Echinoderms and annelids are covered in Volume 3.
The Encyclopedia of the Neuroscience explores all areas of the discipline in its focused entries on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. Each article is written by an expert in that specific domain and peer reviewed by the advisory board before acceptance into the encyclopedia. Each article contains a glossary, introduction, a reference section, and cross-references to other related encyclopedia articles. Written at a level suitable for university undergraduates, the breadth and depth of coverage will appeal beyond undergraduates to professionals and academics in related fields.
Elegant, suggestive, and clarifying, Lewis Thomas's profoundly humane vision explores the world around us and examines the complex interdependence of all things. Extending beyond the usual limitations of biological science and into a vast and wondrous world of hidden relationships, this provocative book explores in personal, poetic essays to topics such as computers, germs, language, music, death, insects, and medicine. Lewis Thomas writes, "Once you have become permanently startled, as I am, by the realization that we are a social species, you tend to keep an eye out for the pieces of evidence that this is, by and large, good for us."
Gregory Bateson was a philosopher, anthropologist, photographer, naturalist, and poet, as well as the husband and collaborator of Margaret Mead. This classic anthology of his major work includes a new Foreword by his daughter, Mary Katherine Bateson. 5 line drawings.