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The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers.*Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research*Delves into data management and addresses how to collect data and use it for discovery*Contains valuable, up-to-date information on how to obtain funding from the federal government
Written to help trainee ophthalmologists, this textbook is now the recognised text on optics for the examinations of the Royal College of Ophthalmologists and the Royal Surgical Colleges. It approaches the subject from first principles and assumes no previous knowledge of optics. The book has been kept as simple as possible and is liberally complemented with diagrams designed to be easily understood and memorised. Only the most fundamental and clinically useful mathematical formulae are quoted, and the optical principles are applied to clinical situations. Ophthalmology examinations have changed substantially since the last edition was written and a total rewrite of this essential guide has become necessary. The third edition has been made more comprehensive and detailed to keep up with these changes and incorporates three new chapters: refractive surgery, contact lenses and lasers. Other new material includes photometry, visual acuity, contrast sensitivity, colour vision, absorptive lenses, fluorescence, ultrasound, and the specular microscope.
A comprehensive, evidence-based introduction to the principles and practices of patient communication in a clinical setting Endorsed by the American Academy on Communication for Healthcare Updated and expanded by a multidisciplinary team of medical experts, Smith’s Patient-Centered Interviewing, Third Edition presents a step-by-step methodology for mastering every aspect of the medical interview. You will learn how to confidently obtain from patients accurate biomedical facts, as well as critical personal, social, and emotional information, allowing you to make precise diagnoses, develop effective treatment plans, and forge strong clinician-patient relationships. The most evidence-based guide available on this topic, Smith’s Patient-Centered Interviewing applies the proven 5-Step approach, which integrates patient- and clinician-centered skills to improve effectiveness without adding extra time to the interview’s duration. Smith’s Patient-Centered Interviewing covers everything from patient-centered and clinician-centered interviewing skills, such as: Patient education Motivating for behavior change Breaking bad news Managing different personality styles Increasing personal awareness in mindful practice Nonverbal communication Using computers in the exam room Reporting and presenting evaluations Companion video and teaching supplement are available online. Read details inside the book.
The classic reference covering the diagnosis and treatment of all major ophthalmic diseases, as well as neurological and systemic diseases causing visual disturbance-extensively revised and updated Features State-of-the-art coverage of diagnostic techniques and therapeutic interventions for the full range of ophthalmic disorders Chapters dedicated to ophthalmic therapeutics, neuro-ophthalmology, ocular disorders associated with systemic diseases, immunologic diseases of the eye, pediatrics, genetics, preventive ophthalmology and lasers The latest clinical perspectives on such topics as: Treatments for age-related macular degeneration, including anti-VEGF therapies Intraocular steroid injections for retinal diseases Immunomodulatory drugs Treatment of corneal infections Medical and surgical treatments for glaucoma Detailed appendices on visual standards, practical factors in illumination, rehabilitation of the visually handicapped, and special services available to the blind Latest references
A full-color guide to the entire field of clinical endocrinology and its scientific underpinnings – updated with the latest breakthroughs and developments A Doody’s Core Title for 2021! Greenspan’s Basic & Clinical Endocrinology delivers a succinct, leading-edge overview of the underlying molecular biology of the endocrine system and the latest perspectives on the diagnosis and treatment of specific diseases and disorders. Featuring an enhanced design that includes hundreds of full-color illustrations and clinical photographs, Greenspan’s is a true must-have during traditional or integrated courses in endocrinology, endocrinology rotation, or exam prep in internal medicine and endocrinology and as reference for disease management. Greenspan’s provides clinically relevant coverage of metabolic bone disease, pancreatic hormones and diabetes mellitus, hypoglycemia, obesity, geriatric endocrinology, and many other diseases and disorders. Supporting this essential material is a handy appendix of normal hormone reference ranges across the lifespan. Here’s why Greenspan’s is an essential tool for learning how to manage endocrine patients: • The Tenth Edition is enhanced by updated content throughout each chapter • NEW CHAPTERS on Transgender Endocrinology and Disorders of Sexual Determination and Differentiation • Important chapter on Evidence-Based Endocrinology and Clinical Epidemiology • Concise, balanced coverage of both scientific and clinical principles that guide patient management • The best source for current concepts in endocrine pathophysiology to aid clinical decision making • The most practical, current insights into diagnostic testing • More than 270 full-color illustrations and clinical photographs If you are in need of a well-illustrated, completely up-to-date guide to the entire field of clinical endocrinology, this trusted classic belongs on your desk or computer.
50 Studies Every Ophthalmologist Should Know presents key studies that have shaped the practice of ophthalmology. Selected using a rigorous methodology, emphasis has been placed on landmark studies which have influenced current ophthalmology practice guidelines. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. An illustrative clinical case concludes each review, followed by brief information on other relevant studies. This book is a must-read for ophthalmologists, especially those in training or preparing for board review, as well as anyone who wants to learn more about the data behind clinical practice.
Eye cancers vary in presentation depending upon geographic location and access to healthcare. Global Perspectives in Ocular Oncology offers an international platform for leading ocular oncologists and multidisciplinary specialists to highlight worldwide strengths and solutions to the challenges in treating eye cancer. The goal of the book is to provide a universal view on the management of adult and pediatric tumors affecting the eye and ocular adnexa. A range of topics pertinent to the global community have been included. Organized into seven distinct sections, this book covers international collaborations and initiatives, technology and innovations, and novel treatment strategies. In addition, it provides a glimpse into the future of the specialty. The emphasis on sharing perspectives as well as the global and multidisciplinary framework of the book are unique to the market. This work will appeal to a variety of audiences including ocular oncologists and ophthalmic subspecialists, oncologists and other specialists, optometrists, geneticists, allied medical professionals, and trainees entering these disciplines.