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Offering up-to-date coverage of familiar flaviviruses that are spreading into new regions or are causing increasingly severe disease, as well as viruses that are almost unknown in most developed nations, Zika and Other Neglected and Emerging Flaviviruses brings together information that allows for easy comparison of similarities and differences of this viral group in a single, convenient volume. Each chapter includes a brief Introduction, history, the diseases, the virus, the immune response, prevention or treatment, an extensive list of references, and a summary overview. The book concludes with a chapter tying together information about flaviviruses and other potential new microbial threats. - Covers familiar flaviviruses that are spreading into new regions or are causing increasingly severe disease (such as Zika, dengue and West Nile viruses), as well as lesser-knowns viruses such as tick-borne encephalitis virus, Powassan virus, Omsk hemorrhagic fever, and Murray Valley encephalitis virus. - Allows health-related personnel to search for potential treatments and protective responses by examining what measure did or did not work with other, related flaviviruses. - Helps readers understand how to prevent or contain newly emerging viral threats—a particularly timely topic regarding the global spread of COVID-19 and the potential of tick-borne encephalitis to rapidly spread and cause severe illness, panic, and disruption of economies. - Consolidates today's available information on this timely topic into a single, convenient resource.
THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.
Zika virus (ZIKV) is a mosquito-borne member of the Flaviviridae family that historically has been associated with mild febrile illness. However, the recent outbreaks in Brazil in 2015 and its rapid spread throughout South and Central America and the Caribbean, together with its association with severe neurological disorders—including fetal microcephaly and Guillain-Barré syndrome in adults—have changed the historic perspective of ZIKV. Currently, ZIKV is considered an important public health concern that has the potential to affect millions of people worldwide. The significance of ZIKV in human health and the lack of approved vaccines and/or antiviral drugs to combat ZIKV infection have triggered a global effort to develop effective countermeasures to prevent and/or treat ZIKV infection. In this Special Issue of Viruses, we have assembled a collection of 32 research and review articles that cover the more recent advances on ZIKV molecular biology, replication and transmission, virus–host interactions, pathogenesis, epidemiology, vaccine development, antivirals, and viral diagnosis.
Discusses how to fight Ebola, SARS Corona, and other known or emerging human viruses by building on the successes in antiviral therapy of the past decades Written by leading medicinal chemists from academia and industry, this book discusses the entire field of antiviral drug discovery and development from a medicinal chemistry perspective, focusing on antiviral drugs, targets, and viral disease mechanisms. It provides an outlook on emerging pathogens such as Ebola, Zika, West Nile, Lassa, and includes a chapter on SARS Coronoavirus-2 causing the present pandemic. New Drug Development for Known and Emerging Viruses describes the discovery and development process for antiviral agents for different classes of viruses and targets based on the experiences from the nine human viruses for which approved drugs are on the market (HIV, HCV, Influenza, RSV, HBV, HPV, HCMV, HSV, and VZV). It covers the properties and potential of 20 classes of currently approved antivirals, including combination drugs, and looks at novel antiviral strategies against emerging viruses. Covers the entire field of antiviral drug discovery and development Addresses the need for antiviral drugs to combat major health threats such as Ebola, Zika, West Nile, and SARS Coronavirus-2 Summarizes the successes of the past 15 years in developing ground-breaking medicines against 9 major human viruses, both from the medicinal chemistry and the pharmacological angle Discusses practical and strategic challenges in the drug discovery and development process, including screening technologies, latency, and toxicity issues New Developments in Antiviral Drugs is an important book for medicinal chemists, pharmaceutical chemists, virologists, and epidemiologists, and will be of great interest to those in the ;pharmaceutical industry and public health agencies.
An important resource that reviews the various infectious diseases that affect bats and bat populations Bats and Human Health: Ebola, SARS, Rabies and Beyond covers existing literature on viral, bacterial, protozoan, and fungal infections of bats and how these infections affect bat populations. The book also offers an overview of the potential for zoonotic transmission of infectious diseases from bats to humans or domestic animals. While most prior publications on the subject have dealt only with bat viral infections, this text closely covers a wide range of bat infections, from viral and bacterial infections to protist and fungal infections. Chapters on viral infections cover rabies, filoviruses, henipaviruses, and other RNA viruses, as well as information on bat virome studies. The book then provides information on bacterial infections–including arthropod-borne and other bacteria that affect bats–before moving on to protist infections, including apicomplexans and kinetoplastids, and fungal infections, including white-nose syndrome, histoplasma capsulatum, and other fungi. Comprehensive in scope, yet another key feature of this book is a searchable database that includes bat species, bat family, bat diet, bat location, type and classification of infecting microbes, and categories of microbes. This vital resource also: Provides a history and comprehensive overview of bat-borne diseases Incorporates information from the World Health Organization, as well as historical data from the National Libraries of Health and infectious disease journals Covers a variety of diseases including viral infections, bacterial infections, protist infections, and fungal infections Written for microbiologist, bat researchers, and conservationists, Bats and Human Health provides a comprehensive exploration of the various types of microbes that affect bats and their potential to affect human populations.
Approximately 75% of emerging infectious diseases are zoonoses, and the rate of emergence of zoonotic diseases is on the rise. Bats are being increasingly recognised as an important reservoir of zoonotic viruses of different families, including SARS coronavirus, Nipah virus, Hendra virus and Ebola virus. Understanding bats’ role in emerging zoonotic diseases is crucial to this rapidly expanding area of research. Bats and Viruses: A New Frontier of Emerging Infectious Diseases provides an updated overview of research focusing on bat biology and the role bats play as hosts of many major zoonotic viruses. The text covers bat biology, immunology, and genomics. Chapters also delve into the various major bat-borne virus families, including lyssaviruses, paramyxoviruses, coronaviruses, filoviruses and reoviruses, among others. Edited by leaders in the field, Bats and Viruses: A New Frontier of Emerging Infectious Diseases is a timely, invaluable reference for bat researchers studying microbiology, virology and immunology, as well as infectious disease workers and epidemiologists, among others.
For four decades, physicians and other healthcare providers have trusted Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases to provide expert guidance on the diagnosis and treatment of these complex disorders. The 9th Edition continues the tradition of excellence with newly expanded chapters, increased global coverage, and regular updates to keep you at the forefront of this vitally important field. Meticulously updated by Drs. John E. Bennett, Raphael Dolin, and Martin J. Blaser, this comprehensive, two-volume masterwork puts the latest information on challenging infectious diseases at your fingertips. - Provides more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than any other infectious disease resource. - Features an increased focus on antibiotic stewardship; new antivirals for influenza, cytomegalovirus, hepatitis C, hepatitis B., and immunizations; and new recommendations for vaccination against infection with pneumococci, papillomaviruses, hepatitis A, and pertussis. - Covers newly recognized enteroviruses causing paralysis (E-A71, E-D68); emerging viral infections such as Ebola, Zika, Marburg, SARS, and MERS; and important updates on prevention and treatment of C. difficile infection, including new tests that diagnose or falsely over-diagnose infectious diseases. - Offers fully revised content on bacterial pathogenesis, antibiotic use and toxicity, the human microbiome and its effects on health and disease, immunological mechanisms and immunodeficiency, and probiotics and alternative approaches to treatment of infectious diseases. - Discusses up-to-date topics such as use of the new PCR panels for diagnosis of meningitis, diarrhea and pneumonia; current management of infected orthopedic implant infections; newly recognized infections transmitted by black-legged ticks in the USA: Borrelia miyamotoi and Powassan virus; infectious complications of new drugs for cancer; new drugs for resistant bacteria and mycobacteria; new guidelines for diagnosis and therapy of HIV infections; and new vaccines against herpes zoster, influenza, meningococci. - PPID continues its tradition of including leading experts from a truly global community, including authors from Australia, Canada and countries in Europe, Asia, and South America. - Includes regular updates online for the life of the edition. - Features more than 1,500 high-quality, full-color photographs—with hundreds new to this edition. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.
From basic clinical facts to new advanced guidelines, Practical Cardiology: Principles and Approaches covers all aspects of cardiology in one quick and current resource. Packed with useful tips and step-by-step guidance, this updated second edition reviews new drugs, new invasive and noninvasive therapeutic approaches, and new developments in cardiology foundations, imaging modalities, management approaches, and specific interventions for all common cardiovascular disease modalities in all patient care settings. - Offers practical plans of action for all major cardiovascular topics and diseases. - Includes three new chapters on electrophysiology (including tracing interpretation); mechanisms, diagnoses, and therapies; and hypotension, syncope, and sudden cardiac death. - Features updated and expanded content throughout, including new findings, non-ST elevation in specific populations (elderly, women), diabetes in heart disease, and more. - Provides integrated key points that offer quick clinical summaries for all aspects of common cardiovascular conditions. - Contains more than 125 full-color illustrations with many algorithms of diagnostic and therapeutic pathways.
Der neue Band aus der Reihe International Society of Neuropathology wurde anlässlich der British Medical Association (BMA) Awards 2019 wärmstens empfohlen. Die Herausgeber sind Experten des Fachgebiets und beschreiben Infektionen des Nervensystems mit ihren klinischen, pathologischen und genetischen Eigenheiten. Auch seltene Erkrankungen werden in übersichtlichen Kapiteln erläutert, zusammen mit Definitionen, mikrobiologischen Eigenschaften, Epidemiologie, klinischen Ausprägungen, Labortests, Pathologie, Genetik und Behandlungsoptionen.
Offering up-to-date coverage of familiar flaviviruses that are spreading into new regions or are causing increasingly severe disease, as well as viruses that are almost unknown in most developed nations, Zika and Other Neglected and Emerging Flaviviruses brings together information that allows for easy comparison of similarities and differences of this viral group in a single, convenient volume. Each chapter includes a brief Introduction, history, the diseases, the virus, the immune response, prevention or treatment, an extensive list of references, and a summary overview. The book concludes with a chapter tying together information about flaviviruses and other potential new microbial threats. Covers familiar flaviviruses that are spreading into new regions or are causing increasingly severe disease (such as Zika, dengue and West Nile viruses), as well as lesser-knowns viruses such as tick-borne encephalitis virus, Powassan virus, Omsk hemorrhagic fever, and Murray Valley encephalitis virus. Allows health-related personnel to search for potential treatments and protective responses by examining what measure did or did not work with other, related flaviviruses. Helps readers understand how to prevent or contain newly emerging viral threats-a particularly timely topic regarding the global spread of COVID-19 and the potential of tick-borne encephalitis to rapidly spread and cause severe illness, panic, and disruption of economies. Consolidates today's available information on this timely topic into a single, convenient resource.