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In Gene Regulatory Sequences and Human Disease, the Editor will introduce the different technological advances that led to this breakthrough. In addition, several examples will be provided of nucleotide variants in noncoding sequences that have been shown to be associated with various human diseases.

Hearings

United States. Congress. House. Committee on Appropriations

Published: 1932

Total Pages: 1786


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Petri Nets were introduced in the doctoral dissertation by K.A. Petri, titled "Kommunikation mit Automaten" and published in 1962 by University of Bonn. Petri Nets are graphical (the intuitive graphical modeling language) and mathematical (advanced formal analysis method) tool. The concurrence of performed actions is the natural phenomenon due to which Petri Nets are perceived as mathematical tool for modeling concurrent systems. The main idea of this theory was modified by many researchers according to their needs, owing to the unusual "flexibility" of this theory. The present monograph focuses on Petri Nets applications in two main areas: manufacturing (section 1) and computer science (section 2). These two areas have still huge influence on our lives and our world. The theory of Petri Nets is still developing: some directions of investigations are presented in section 3. And at the end there is section 4 including some infesting facts concerning application of Petri Nets in the public area: the analysis and control of public bicycle sharing systems. The monograph shows the results of research works performed with use of Petri Nets in science centers all over the world.
Historical fiction that speculates on how, US Naval rigid airships could have played a part in the war in the Pacific during World War II, if they had continued to evolve after 1935.
Within six months of the devastating attack on Pearl Harbor, the U.S. Navy had checked the Japanese military advance in the Pacific to the extent that the United States could return to its original "Defeat Germany First" strategy. That the Navy was able to accomplish this feat with only six fleet aircraft carriers and little more than 1,000 combat aircraft was not sheer luck but the culmination of more than two decades of determined preparation. This thorough study, with detailed drawings and photographs, explains and illustrates the trial and error process which went into developing the aircraft, airships and ships of the interwar period. The critical factors that shaped Naval Aviation after World War I--naval treaties, fleet tactics, government programs, leadership and organization, as well as the emergence of Marine Corps and Coast Guard aviation--are discussed in depth.
In this third volume of The Quantum Theory of Fields, available for the first time in paperback, Nobel Laureate Steven Weinberg continues his masterly exposition of quantum field theory. This volume presents a self-contained, up-to-date and comprehensive introduction to supersymmetry, a highly active area of theoretical physics. The text introduces and explains a broad range of topics, including supersymmetric algebras, supersymmetric field theories, extended supersymmetry, supergraphs, non-perturbative results, theories of supersymmetry in higher dimensions, and supergravity. A thorough review is given of the phenomenological implications of supersymmetry, including theories of both gauge and gravitationally-mediated supersymmetry breaking. Also provided is an introduction to mathematical techniques, based on holomorphy and duality, that have proved so fruitful in recent developments. This book contains much material not found in other books on supersymmetry, including previously unpublished results. Exercises are included.
Based on more than 30 years of research on differential theories of gratings, this book describes developments in differential theory for applications in spectroscopy, acoustics, X-ray instrumentation, optical communication, information processing, photolithography, high-power lasers, high-precision engineering, and astronomy. Introducing the Fast Fourier Factorization approach to improve the convergence of a truncated series, the book examines multilayers, stacked gratings, crossed gratings, photonic crystals, and isotropic and anisotropic materials; techniques and examples in grating design; and Maxwell equations in a truncated Fourier space.
Comparative Biology of the Normal Lung, Second Edition, offers a rigorous and comprehensive reference for all those involved in pulmonary research. This fully updated work is divided into sections on anatomy and morphology, physiology, biochemistry, and immunological response. It continues to provide a unique comparative perspective on the mammalian lung. This edition includes several new chapters and expanded content, including aging and development of the normal lung, mechanical properties of the lung, genetic polymorphisms, the comparative effect of stress of pulmonary immune function, oxygen signaling in the mammalian lung and much more. By addressing scientific advances and critical issues in lung research, this 2nd edition is a timely and valuable work on comparative data for the interpretation of studies of animal models as compared to the human lung. - Edited and authored by experts in the field to provide an excellent and timely review of cross-species comparisons that will help you interpret and compare data from animal studies to human findings - Incorporates lung anatomy and physiology, cell specific interactions and immunological responses to provide you with a single and unique multidisciplinary source on the comparative biology of the normal lung - Includes new and expanded content on neonatal and aged lungs, developmental processes, cell signaling, antioxidants, airway cells, safety pharmacology and much more - Section IV on Physical and Immunological Defenses has been significantly updated with 9 new chapters and an increased focus on the pulmonary immunological system