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This book documents the fascinating history of radiological techniques that use contrast agents. The text includes many of the fundamental documentary sources that bring to life the social and scientific background of the discoveries, the personalities of the discoverers, and implementation of new technologies. Such agents when used with X-rays allow clinicians to distinguish anatomical structures with nearly identical densities. Focus is on urological and angiographic uses of contrast agents. Key selling features: Documents and thoroughly references the history of contrast agent development Reviews the priority and importance of patents Discusses the role that important individual scientists and leading research institutions have played in technology development and implementation
This open access book gives a complete and comprehensive introduction to the fields of medical imaging systems, as designed for a broad range of applications. The authors of the book first explain the foundations of system theory and image processing, before highlighting several modalities in a dedicated chapter. The initial focus is on modalities that are closely related to traditional camera systems such as endoscopy and microscopy. This is followed by more complex image formation processes: magnetic resonance imaging, X-ray projection imaging, computed tomography, X-ray phase-contrast imaging, nuclear imaging, ultrasound, and optical coherence tomography.
A practical clinically relevant introduction to diagnostic radiology Introduction to Basic Radiology is written to provide non-radiologists with the level of knowledge necessary to order correct radiological examinations, improve image interpretation, and enhance their interpretation of various radiological manifestations. The book focuses on the clinical scenarios most often encountered in daily practice and discusses practical imaging techniques and protocols used to address common problems. Relevant case scenarios are included to demonstrate how to reach a specific diagnosis. Introduction to Basic Radiology is divided into ten chapters. The first two chapters provide basic information on various diagnostic imaging techniques and control agents. Each of the following chapters discuss imaging of specific organ systems and begin with a description of the imaging modality of choice and illustrates the relevant features to help simplify the differential diagnosis. You will also find important chapters on pediatric radiology and women's imaging. Unlike other introductory texts on the subject, this book treats diagnosis from a practical point of view. Rather than discuss various diseases and classify them from the pathologic standpoint, Introduction to Basic Radiology utilizes cases from the emergency room and physician's offices and uses a practical approach to reach a diagnosis. The cases walk you through a radiology expert’s analysis of imaging patterns. These cases are presented progressively, with the expert's thinking process described in detail. The cases highlight clinical presentation, clinical suspicion, modality of choice, radiologic technique, and pertinent imaging features of common disease processes.
Spectral, Photon Counting Computed Tomography is a comprehensive cover of the latest developments in the most prevalent imaging modality (x-ray computed tomography (CT)) in its latest incarnation: Spectral, Dual-Energy, and Photon Counting CT. Disadvantages of the conventional single-energy technique used by CT technology are that different materials cannot be distinguished and that the noise is larger. To address these problems, a novel spectral CT concept has been proposed. Spectral Dual-Energy CT (DE-CT) acquires two sets of spectral data, and Spectral Photon Counting CT (PC-CT) detects energy of x-ray photons to reveal additional material information of objects by using novel energy-sensitive, photon-counting detectors. The K-edge imaging may be a gateway for functional or molecular CT. The book covers detectors and electronics, image reconstruction methods, image quality assessments, a simulation tool, nanoparticle contrast agents, and clinical applications for spectral CT.
Journalists, always very direct and in search of sensation, essentially asked me two questions on the occasion of this workshop: What were the goals of the meeting? With the improvement of diagnosis through the development of image techniques, didn't the contrast media already have their future behind them? Many answers were provided during the course of the workshop, and in order to best answer the journalists I proposed the following synopsis. 1. Since the 1979 Colorado Springs workshop organized by E. Lasser, progress has been so rapid and the newly available works so numerous that another meeting on an international level for the purpose of pre senting and discussing these advances appeared indispensable. Why not then in Europe and why not in Lyon? To expand on this progress, by 1981 the new contrast media with less-hyperosmolar molecules, still in the trial stage in 1979, were al most all available commercially for angiography, albeit at prohibitive prices. The advantages of these various media are becoming better known; moreover, in the wake of Lasser's work, our understanding of the pathophysiology of their noxious effects is also advancing rapidly owing to the use of models (for the target organs: heart, vessel wall, nervous system, kidney; and for the more general reactions: blood cells, coagulation, complement system, circulating enzymatic systems). In addition, further new molecules are currently being studied in re search laboratories. 2.
This book is a comprehensive guide to contrast-enhanced mammography (CEM), a novel advanced mammography technique using dual-energy mammography in combination with intravenous contrast administration in order to increase the diagnostic performance of digital mammography. Readers will find helpful information on the principles of CEM and indications for the technique. Detailed attention is devoted to image interpretation, with presentation of case examples and highlighting of pitfalls and artifacts. Other topics to be addressed include the establishment of a CEM program, the comparative merits of CEM and MRI, and the roles of CEM in screening populations and monitoring of response to neoadjuvant chemotherapy. CEM became commercially available in 2011 and is increasingly being used in clinical practice owing to its superiority over full-field digital mammography. This book will be an ideal source of knowledge and guidance for all who wish to start using the technique or to learn more about it.
Containing chapter contributions from over 130 experts, this unique publication is the first handbook dedicated to the physics and technology of X-ray imaging, offering extensive coverage of the field. This highly comprehensive work is edited by one of the world’s leading experts in X-ray imaging physics and technology and has been created with guidance from a Scientific Board containing respected and renowned scientists from around the world. The book's scope includes 2D and 3D X-ray imaging techniques from soft-X-ray to megavoltage energies, including computed tomography, fluoroscopy, dental imaging and small animal imaging, with several chapters dedicated to breast imaging techniques. 2D and 3D industrial imaging is incorporated, including imaging of artworks. Specific attention is dedicated to techniques of phase contrast X-ray imaging. The approach undertaken is one that illustrates the theory as well as the techniques and the devices routinely used in the various fields. Computational aspects are fully covered, including 3D reconstruction algorithms, hard/software phantoms, and computer-aided diagnosis. Theories of image quality are fully illustrated. Historical, radioprotection, radiation dosimetry, quality assurance and educational aspects are also covered. This handbook will be suitable for a very broad audience, including graduate students in medical physics and biomedical engineering; medical physics residents; radiographers; physicists and engineers in the field of imaging and non-destructive industrial testing using X-rays; and scientists interested in understanding and using X-ray imaging techniques. The handbook's editor, Dr. Paolo Russo, has over 30 years’ experience in the academic teaching of medical physics and X-ray imaging research. He has authored several book chapters in the field of X-ray imaging, is Editor-in-Chief of an international scientific journal in medical physics, and has responsibilities in the publication committees of international scientific organizations in medical physics. Features: Comprehensive coverage of the use of X-rays both in medical radiology and industrial testing The first handbook published to be dedicated to the physics and technology of X-rays Handbook edited by world authority, with contributions from experts in each field
With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.
Varicose Veins and Related Disorders focuses on the valvular incompetence in the superficial veins. It evaluates the widespread valve failure in superficial and deep veins. It addresses the congenital venous disorders and the complication of superficial vein incompetence and varicose veins. Some of the topics covered in the book are the differential diagnosis and treatment of edema of the lower limb; acute and subacute deep vein thrombosis in the lower limb; venous and other vascular disorders affecting the upper limb; and role of perforator. The book discusses vascular factors in the management of leg ulcers and the interrelationship of venous disorders with ischemia and other conditions. It also tackles the surgical treatment of superficial vein incompetence; the functional phlebography in venous disorders of the lower limbs; and valveless syndrome and weak vein syndrome. The book can provide useful information to doctors, vascular surgeons, students, and researchers.
In 1890, Professor Arthur Willis Goodspeed, a professor of physics at Pennsylvania USA was working with an English born photographer, William N Jennings, when they accidentally produced a Röntgen Ray picture. Unfortunately, the significance of their findings were overlooked, and the formal discovery of X-rays was credited to Wilhelm Roentgen in 1895. The discovery has since transformed the practice of medicine, and over the course of the past 130 years, the development of new radiological techniques has continued to grow. The impact has been seen in virtually every hospital in the world, from the routine use of ultrasound for pregnancy scans, through to the diagnosis of complex medical issues such as brain tumours. More subtly, X-rays were also used in the discovery of DNA and in military combat, and their social influence through popular culture can be seen in cartoons, books, movies and art. Written by two radiologists who have a passion for the history of their field, The History of Radiology is a beautifully illustrated review of the remarkable developments within radiology and the scientists and pioneers who were involved. This engaging and authoritative history will appeal to a wide audience including medical students studying for the Diploma in the History of Medicine of the Society of Apothecaries (DHMSA), doctors, medical physicists, medical historians and radiographers.